Number of solution states of bradykinin from ion mobility and mass spectrometry measurements NA Pierson, L Chen, SJ Valentine, DH Russell, DE Clemmer Journal of the American Chemical Society 133 (35), 13810-13813, 2011 | 168 | 2011 |
Cis–Trans Isomerizations of Proline Residues Are Key to Bradykinin Conformations NA Pierson, L Chen, DH Russell, DE Clemmer Journal of the American Chemical Society 135 (8), 3186-3192, 2013 | 113 | 2013 |
In-depth structural characterization of Kadcyla®(ado-trastuzumab emtansine) and its biosimilar candidate L Chen, L Wang, H Shion, C Yu, YQ Yu, L Zhu, M Li, W Chen, K Gao MAbs 8 (7), 1210-1223, 2016 | 111 | 2016 |
Microwave-assisted graft copolymerization of ε-caprolactone onto chitosan via the phthaloyl protection method L Liu, Y Li, Y Fang, L Chen Carbohydrate Polymers 60 (3), 351-356, 2005 | 95 | 2005 |
Metal-induced conformational changes of human metallothionein-2A: a combined theoretical and experimental study of metal-free and partially metalated intermediates SH Chen, L Chen, DH Russell Journal of the American Chemical Society 136 (26), 9499-9508, 2014 | 78 | 2014 |
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment A Balestrini, V Joseph, M Dourado, RM Reese, SD Shields, L Rougé, ... Journal of Experimental Medicine 218 (4), 2021 | 75 | 2021 |
Self‐Catalysis of Phthaloylchitosan for Graft Copolymerization of ε‐Caprolactone with Chitosan L Liu, L Chen, Y Fang Macromolecular rapid communications 27 (23), 1988-1994, 2006 | 58 | 2006 |
How alkali metal ion binding alters the conformation preferences of gramicidin A: a molecular dynamics and ion mobility study L Chen, YQ Gao, DH Russell The Journal of Physical Chemistry A 116 (1), 689-696, 2012 | 51 | 2012 |
Molecular dynamics and ion mobility spectrometry study of model β-hairpin peptide, trpzip1 L Chen, Q Shao, YQ Gao, DH Russell The journal of physical chemistry A 115 (17), 4427-4435, 2011 | 36 | 2011 |
An experimental study of the solvent-dependent self-assembly/disassembly and conformer preferences of gramicidin A L Chen, SH Chen, DH Russell Analytical chemistry 85 (16), 7826-7833, 2013 | 33 | 2013 |
Changes in organic anion transporting polypeptide uptake in HEK293 overexpressing cells in the presence and absence of human plasma CM Bowman, E Chen, L Chen, YC Chen, X Liang, M Wright, Y Chen, ... Drug Metabolism and Disposition 48 (1), 18-24, 2020 | 21 | 2020 |
Gas and liquid phase diffusivities of isomeric metal complexes derived from multifold ring-closing metatheses: ion mobility mass spectrometry trumps DOSY NMR T Fiedler, L Chen, ND Wagner, DH Russell, JA Gladysz Organometallics 35 (12), 2071-2075, 2016 | 19 | 2016 |
A technical overview of supercritical fluid chromatography-mass spectrometry (SFC-MS) and its recent applications in pharmaceutical research and development L Chen, B Dean, X Liang Drug Discovery Today: Technologies 40, 69-75, 2021 | 15 | 2021 |
Stereoselective supercritical fluidic chromatography–mass spectrometry (SFC-MS) as a fast bioanalytical tool to assess chiral inversion in vivo and in vitro L Chen, B Dean, H La, Y Chen, X Liang International Journal of Mass Spectrometry 444, 116172, 2019 | 14 | 2019 |
Evaluation of polysaccharide-based chiral stationary phases in modern SFC–MS/MS for enantioselective bioanalysis L Chen, B Dean, X Liang Bioanalysis 11 (04), 251-266, 2019 | 14 | 2019 |
Translational and pharmacokinetic‐pharmacodynamic application for the clinical development of GDC‐0334, a novel TRPA1 inhibitor P Chan, HT Ding, BM Liederer, J Mao, P Belloni, L Chen, SS Gao, ... Clinical and Translational Science 14 (5), 1945-1954, 2021 | 9 | 2021 |
Phase I and scintigraphy studies to evaluate safety, tolerability, pharmacokinetics, and lung deposition of inhaled GDC‐0214 in healthy volunteers R Zhu, H Chen, J Galanter, G She, F Cai, MR Durk, Y Zou, L Chen, ... Clinical and Translational Science 15 (5), 1225-1237, 2022 | 3 | 2022 |
A multiplatform approach for the discovery of novel drug-induced kidney injury biomarkers L Chen, J Smith, J Mikl, R Fryer, F Pack, BJ Williams, JA Phillips, ... Chemical Research in Toxicology 30 (10), 1823-1834, 2017 | 3 | 2017 |
A phase 1 study to evaluate the safety, tolerability, and pharmacokinetics of inhaled GDC-0214, a JAK1 inhibitor, as single-and multiple-ascending doses in healthy volunteers R Owen, J Galanter, R Zhu, F Cai, J Tom, C Wynne, M Durk, L Chen, ... Journal of Allergy and Clinical Immunology 145 (2), AB17, 2020 | 2 | 2020 |
Multiple attribute monitoring methodologies for complex samples YQ Yu, HY Shion, SJ Berger, J Fang, L Chen, M Du US Patent App. 15/716,659, 2018 | 2 | 2018 |