Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression M Manczak, TS Anekonda, E Henson, BS Park, J Quinn, PH Reddy Human molecular genetics 15 (9), 1437-1449, 2006 | 1352 | 2006 |
Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies JS Bhatti, GK Bhatti, PH Reddy Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (5 …, 2017 | 1153 | 2017 |
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease PH Reddy, MF Beal Trends in molecular medicine 14 (2), 45-53, 2008 | 1103 | 2008 |
Role of glutamate and NMDA receptors in Alzheimer’s disease R Wang, PH Reddy Journal of Alzheimer's Disease 57 (4), 1041-1048, 2017 | 912 | 2017 |
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for … M Manczak, MJ Calkins, PH Reddy Human molecular genetics 20 (13), 2495-2509, 2011 | 844 | 2011 |
Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease S Pugazhenthi, L Qin, PH Reddy Biochimica et biophysica acta (BBA)-molecular basis of disease 1863 (5 …, 2017 | 722 | 2017 |
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease MJ Calkins, M Manczak, P Mao, U Shirendeb, PH Reddy Human molecular genetics 20 (23), 4515-4529, 2011 | 657 | 2011 |
Is Alzheimer's disease a type 3 diabetes? A critical appraisal R Kandimalla, V Thirumala, PH Reddy Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (5 …, 2017 | 655 | 2017 |
Mitochondria-targeted antioxidants protect against amyloid-β toxicity in Alzheimer's disease neurons M Manczak, P Mao, MJ Calkins, A Cornea, AP Reddy, MP Murphy, ... Journal of Alzheimer's Disease 20 (s2), S609-S631, 2010 | 537 | 2010 |
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA PH Reddy, M Williams, V Charles, L Garrett, L Pike-Buchanan, ... Nature genetics 20 (2), 198-202, 1998 | 524 | 1998 |
Amyloid precursor protein‐mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease PH Reddy Journal of neurochemistry 96 (1), 1-13, 2006 | 458 | 2006 |
Differential expression of oxidative phosphorylation genes in patients with Alzheimer’s disease: implications for early mitochondrial dysfunction and oxidative damage M Manczak, BS Park, Y Jung, PH Reddy Neuromolecular medicine 5, 147-162, 2004 | 456 | 2004 |
Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction PH Reddy, G Mani, BS Park, J Jacques, G Murdoch, W Whetsell Jr, ... Journal of Alzheimer's Disease 7 (2), 103-117, 2005 | 451 | 2005 |
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and … M Manczak, PH Reddy Human molecular genetics 21 (11), 2538-2547, 2012 | 449 | 2012 |
Amyloid-beta and phosphorylated tau accumulations cause abnormalities at synapses of Alzheimer’s disease neurons R Rajmohan, PH Reddy Journal of Alzheimer's Disease 57 (4), 975-999, 2017 | 422 | 2017 |
Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95 Y Sun, A Savanenin, PH Reddy, YF Liu Journal of Biological Chemistry 276 (27), 24713-24718, 2001 | 410 | 2001 |
Are mitochondria critical in the pathogenesis of Alzheimer's disease? PH Reddy, MF Beal Brain Research Reviews 49 (3), 618-632, 2005 | 409 | 2005 |
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics PH Reddy, R Tripathi, Q Troung, K Tirumala, TP Reddy, V Anekonda, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (5), 639-649, 2012 | 406 | 2012 |
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage U Shirendeb, AP Reddy, M Manczak, MJ Calkins, P Mao, DA Tagle, ... Human molecular genetics 20 (7), 1438-1455, 2011 | 398 | 2011 |
Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change … PH Reddy, S McWeeney, BS Park, M Manczak, RV Gutala, D Partovi, ... Human molecular genetics 13 (12), 1225-1240, 2004 | 394 | 2004 |