关注
Nealia House
Nealia House
Postdoctoral Fellow, Dana-Farber Cancer Institute/Harvard Medical School
在 dfci.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Repeat instability during DNA repair: Insights from model systems
K Usdin, NCM House, CH Freudenreich
Critical reviews in biochemistry and molecular biology 50 (2), 142-167, 2015
1902015
Chromatin modifications and DNA repair: beyond double-strand breaks
NCM House, MR Koch, CH Freudenreich
Frontiers in genetics 5, 296, 2014
1402014
Patching broken DNA: nucleosome dynamics and the repair of DNA breaks
O Gursoy-Yuzugullu, N House, BD Price
Journal of molecular biology 428 (9), 1846-1860, 2016
1202016
Role of recombination and replication fork restart in repeat instability
EJ Polleys, NCM House, CH Freudenreich
DNA repair 56, 156-165, 2017
512017
NuA4 initiates dynamic histone H4 acetylation to promote high-fidelity sister chromatid recombination at postreplication gaps
NCM House, JH Yang, SC Walsh, JM Moy, CH Freudenreich
Molecular cell 55 (6), 818-828, 2014
512014
Sequence and nuclease requirements for breakage and healing of a structure-forming (AT) n sequence within fragile site FRA16D
S Kaushal, CE Wollmuth, K Das, SE Hile, SB Regan, RP Barnes, ...
Cell reports 27 (4), 1151-1164. e5, 2019
462019
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair
JV Layer, L Debaize, A Van Scoyk, NC House, AJ Brown, Y Liu, ...
Proceedings of the National Academy of Sciences 117 (44), 27566-27577, 2020
232020
The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae
MR Koch, NCM House, CM Cosetta, RM Jong, CG Salomon, CE Joyce, ...
Genetics 208 (3), 963-976, 2018
152018
Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126
NCM House, EJ Polleys, I Quasem, M De la Rosa Mejia, CE Joyce, ...
Elife 8, e53362, 2019
102019
BLU-222, an investigational, potent, and selective CDK2 inhibitor, demonstrated robust antitumor activity in CCNE1-amplified ovarian cancer models
V Brown, P Ramsden, N House, R Vargas, J Guo, R Wang, R Lobbari, ...
Proceedings of the American Association for Cancer Research Annual Meeting …, 2022
72022
Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage
NCM House, R Parasuram, JV Layer, BD Price
Plos one 15 (12), e0237759, 2020
72020
Chromatin modifications and DNA repair: beyond double-strand breaks. Front Genet 5: 296
NC House, MR Koch, CH Freudenreich
52014
CDK2 regulates collapsed replication fork repair in CCNE1-amplified ovarian cancer cells via homologous recombination
VE Brown, SL Moore, M Chen, N House, P Ramsden, HJ Wu, S Ribich, ...
NAR cancer 5 (3), zcad039, 2023
42023
CDK2 inhibition with BLU-222 in combination with ribociclib demonstrates robust antitumor activity in pre-clinical models of CDK4/6 inhibitor-naïve and-resistant HR+/HER2 …
V Brown, N House, P Ramsden, K Ho, HJ Wu, E Wilker, J Guo, M Chen, ...
Cancer Res. 83, P6-10, 2023
22023
BLU-222, a potent and highly selective CDK2 inhibitor, demonstrated antitumor activity as monotherapy and as combination treatment in CCNE1-aberrant endometrial cancer models
N House, V Brown, L Yuan, M Chen, S Lee, R Wu, L Muthuswamy, ...
Cancer Research 84 (6_Supplement), 1959-1959, 2024
2024
Abstract P6-10-07: CDK2 inhibition with BLU-222 in combination with ribociclib demonstrates robust antitumor activity in pre-clinical models of CDK4/6 inhibitor-naïve and …
V Brown, N House, P Ramsden, K Ho, HJ Wu, E Wilker, J Guo, M Chen, ...
Cancer Research 83 (5_Supplement), P6-10-07-P6-10-07, 2023
2023
Saccharomyces cerevisiae H2A copies differentially contribute to recombination and CAG/CTG repeat maintenance, with a role for H2A.1 threonine 126
NCM House, EJ Polleys, I Quasem, CE Joyce, O Takacsi-Nagy, ...
bioRxiv, 331413, 2018
2018
129 The molecular mechanism of breakage at fragile site FRA16D
S Kaushal, SMA Lee, N House, K Gnanapradeepan, A Snider, XA Su, ...
Journal of Biomolecular Structure and Dynamics 31 (sup1), 83-83, 2013
2013
A role for histone H2A threonine phosphorylation in prevention of CAG/CTG repeat instability
N House, C Joyce, CH Freudenreich
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 90 (1), 111-111, 2012
2012
Chromatin and the CAG trinucleotide repeat: The contribution of histone H2A and the chromatin remodeling complex Isw1 to the maintenance of CAG/CTG repeat stability and …
N House
Tufts University, 2009
2009
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