Repeat instability during DNA repair: Insights from model systems K Usdin, NCM House, CH Freudenreich Critical reviews in biochemistry and molecular biology 50 (2), 142-167, 2015 | 190 | 2015 |
Chromatin modifications and DNA repair: beyond double-strand breaks NCM House, MR Koch, CH Freudenreich Frontiers in genetics 5, 296, 2014 | 140 | 2014 |
Patching broken DNA: nucleosome dynamics and the repair of DNA breaks O Gursoy-Yuzugullu, N House, BD Price Journal of molecular biology 428 (9), 1846-1860, 2016 | 120 | 2016 |
Role of recombination and replication fork restart in repeat instability EJ Polleys, NCM House, CH Freudenreich DNA repair 56, 156-165, 2017 | 51 | 2017 |
NuA4 initiates dynamic histone H4 acetylation to promote high-fidelity sister chromatid recombination at postreplication gaps NCM House, JH Yang, SC Walsh, JM Moy, CH Freudenreich Molecular cell 55 (6), 818-828, 2014 | 51 | 2014 |
Sequence and nuclease requirements for breakage and healing of a structure-forming (AT) n sequence within fragile site FRA16D S Kaushal, CE Wollmuth, K Das, SE Hile, SB Regan, RP Barnes, ... Cell reports 27 (4), 1151-1164. e5, 2019 | 46 | 2019 |
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair JV Layer, L Debaize, A Van Scoyk, NC House, AJ Brown, Y Liu, ... Proceedings of the National Academy of Sciences 117 (44), 27566-27577, 2020 | 23 | 2020 |
The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae MR Koch, NCM House, CM Cosetta, RM Jong, CG Salomon, CE Joyce, ... Genetics 208 (3), 963-976, 2018 | 15 | 2018 |
Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126 NCM House, EJ Polleys, I Quasem, M De la Rosa Mejia, CE Joyce, ... Elife 8, e53362, 2019 | 10 | 2019 |
BLU-222, an investigational, potent, and selective CDK2 inhibitor, demonstrated robust antitumor activity in CCNE1-amplified ovarian cancer models V Brown, P Ramsden, N House, R Vargas, J Guo, R Wang, R Lobbari, ... Proceedings of the American Association for Cancer Research Annual Meeting …, 2022 | 7 | 2022 |
Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage NCM House, R Parasuram, JV Layer, BD Price Plos one 15 (12), e0237759, 2020 | 7 | 2020 |
Chromatin modifications and DNA repair: beyond double-strand breaks. Front Genet 5: 296 NC House, MR Koch, CH Freudenreich | 5 | 2014 |
CDK2 regulates collapsed replication fork repair in CCNE1-amplified ovarian cancer cells via homologous recombination VE Brown, SL Moore, M Chen, N House, P Ramsden, HJ Wu, S Ribich, ... NAR cancer 5 (3), zcad039, 2023 | 4 | 2023 |
CDK2 inhibition with BLU-222 in combination with ribociclib demonstrates robust antitumor activity in pre-clinical models of CDK4/6 inhibitor-naïve and-resistant HR+/HER2 … V Brown, N House, P Ramsden, K Ho, HJ Wu, E Wilker, J Guo, M Chen, ... Cancer Res. 83, P6-10, 2023 | 2 | 2023 |
BLU-222, a potent and highly selective CDK2 inhibitor, demonstrated antitumor activity as monotherapy and as combination treatment in CCNE1-aberrant endometrial cancer models N House, V Brown, L Yuan, M Chen, S Lee, R Wu, L Muthuswamy, ... Cancer Research 84 (6_Supplement), 1959-1959, 2024 | | 2024 |
Abstract P6-10-07: CDK2 inhibition with BLU-222 in combination with ribociclib demonstrates robust antitumor activity in pre-clinical models of CDK4/6 inhibitor-naïve and … V Brown, N House, P Ramsden, K Ho, HJ Wu, E Wilker, J Guo, M Chen, ... Cancer Research 83 (5_Supplement), P6-10-07-P6-10-07, 2023 | | 2023 |
Saccharomyces cerevisiae H2A copies differentially contribute to recombination and CAG/CTG repeat maintenance, with a role for H2A.1 threonine 126 NCM House, EJ Polleys, I Quasem, CE Joyce, O Takacsi-Nagy, ... bioRxiv, 331413, 2018 | | 2018 |
129 The molecular mechanism of breakage at fragile site FRA16D S Kaushal, SMA Lee, N House, K Gnanapradeepan, A Snider, XA Su, ... Journal of Biomolecular Structure and Dynamics 31 (sup1), 83-83, 2013 | | 2013 |
A role for histone H2A threonine phosphorylation in prevention of CAG/CTG repeat instability N House, C Joyce, CH Freudenreich BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 90 (1), 111-111, 2012 | | 2012 |
Chromatin and the CAG trinucleotide repeat: The contribution of histone H2A and the chromatin remodeling complex Isw1 to the maintenance of CAG/CTG repeat stability and … N House Tufts University, 2009 | | 2009 |