Identification of a candidate therapeutic autophagy-inducing peptide S Shoji-Kawata, R Sumpter, M Leveno, GR Campbell, Z Zou, L Kinch, ... Nature 494 (7436), 201-206, 2013 | 828 | 2013 |
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens N Zhou, Y Jiang, TR Bergquist, AJ Lee, BZ Kacsoh, AW Crocker, ... Genome biology 20, 1-23, 2019 | 390 | 2019 |
An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders SA Baker, L Chen, AD Wilkins, P Yu, O Lichtarge, HY Zoghbi Cell 152 (5), 984-996, 2013 | 242 | 2013 |
Automated hypothesis generation based on mining scientific literature S Spangler, AD Wilkins, BJ Bachman, M Nagarajan, T Dayaram, P Haas, ... Proceedings of the 20th ACM SIGKDD international conference on Knowledge …, 2014 | 185 | 2014 |
Single nucleotide variations: biological impact and theoretical interpretation P Katsonis, A Koire, SJ Wilson, TK Hsu, RC Lua, AD Wilkins, O Lichtarge Protein Science 23 (12), 1650-1666, 2014 | 149 | 2014 |
Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor SM Peterson, TF Pack, AD Wilkins, NM Urs, DJ Urban, CE Bass, ... Proceedings of the National Academy of Sciences 112 (22), 7097-7102, 2015 | 107 | 2015 |
Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity AM Schönegge, J Gallion, LP Picard, AD Wilkins, C Le Gouill, M Audet, ... Nature communications 8 (1), 2169, 2017 | 84 | 2017 |
Evolutionary trace for prediction and redesign of protein functional sites A Wilkins, S Erdin, R Lua, O Lichtarge Computational Drug Discovery and Design, 29-42, 2012 | 77 | 2012 |
Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2 BK Choi, T Dayaram, N Parikh, AD Wilkins, M Nagarajan, IB Novikov, ... Proceedings of the National Academy of Sciences 115 (42), 10666-10671, 2018 | 53 | 2018 |
Disentangling evolutionary signals: conservation, specificity determining positions and coevolution. Implication for catalytic residue prediction E Teppa, AD Wilkins, M Nielsen, CM Buslje BMC bioinformatics 13, 1-8, 2012 | 47 | 2012 |
Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation YM Sung, AD Wilkins, GJ Rodriguez, TG Wensel, O Lichtarge Proceedings of the National Academy of Sciences 113 (13), 3539-3544, 2016 | 43 | 2016 |
Predicting future scientific discoveries based on a networked analysis of the past literature M Nagarajan, AD Wilkins, BJ Bachman, IB Novikov, S Bao, PJ Haas, ... Proceedings of the 21th ACM SIGKDD International Conference on Knowledge …, 2015 | 42 | 2015 |
Prediction and redesign of protein–protein interactions RC Lua, DC Marciano, P Katsonis, AK Adikesavan, AD Wilkins, ... Progress in biophysics and molecular biology 116 (2-3), 194-202, 2014 | 39 | 2014 |
The use of evolutionary patterns in protein annotation AD Wilkins, BJ Bachman, S Erdin, O Lichtarge Current opinion in structural biology 22 (3), 316-325, 2012 | 34 | 2012 |
Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases E Young, ZY Zheng, AD Wilkins, HT Jeong, M Li, O Lichtarge, EC Chang Molecular and cellular biology, 2014 | 33 | 2014 |
Evolution: a guide to perturb protein function and networks O Lichtarge, A Wilkins Current opinion in structural biology 20 (3), 351-359, 2010 | 32 | 2010 |
The 4 3Σ+ state of NaK: Potential energy curve and hyperfine structure P Burns, L Sibbach-Morgus, AD Wilkins, F Halpern, L Clarke, RD Miles, ... The Journal of chemical physics 119 (9), 4743-4754, 2003 | 30 | 2003 |
UET: a database of evolutionarily-predicted functional determinants of protein sequences that cluster as functional sites in protein structures RC Lua, SJ Wilson, DM Konecki, AD Wilkins, E Venner, DH Morgan, ... Nucleic acids research 44 (D1), D308-D312, 2016 | 29 | 2016 |
Accounting for epistatic interactions improves the functional analysis of protein structures AD Wilkins, E Venner, DC Marciano, S Erdin, B Atri, RC Lua, O Lichtarge Bioinformatics 29 (21), 2714-2721, 2013 | 26 | 2013 |
Experimental study of the NaK 3Π3 double minimum state L Morgus, P Burns, RD Miles, AD Wilkins, U Ogba, AP Hickman, ... The Journal of chemical physics 122 (14), 2005 | 26 | 2005 |