| Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ... Genome biology 18, 1-15, 2017 | 456 | 2017 |
| Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice T Aida, K Chiyo, T Usami, H Ishikubo, R Imahashi, Y Wada, KF Tanaka, ... Genome biology 16, 1-11, 2015 | 305 | 2015 |
| Atypical behaviour and connectivity in SHANK3-mutant macaques Y Zhou, J Sharma, Q Ke, R Landman, J Yuan, H Chen, DS Hayden, ... Nature 570 (7761), 326-331, 2019 | 221 | 2019 |
| Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions DS Roy, YG Park, ME Kim, Y Zhang, SK Ogawa, N DiNapoli, X Gu, ... Nature communications 13 (1), 1799, 2022 | 140 | 2022 |
| Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice T Aida, J Yoshida, M Nomura, A Tanimura, Y Iino, M Soma, N Bai, Y Ito, ... Neuropsychopharmacology 40 (7), 1569-1579, 2015 | 137 | 2015 |
| Distinct subnetworks of the thalamic reticular nucleus Y Li, VG Lopez-Huerta, X Adiconis, K Levandowski, S Choi, SK Simmons, ... Nature, 1-6, 2020 | 135 | 2020 |
| Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance W Cui, H Mizukami, M Yanagisawa, T Aida, M Nomura, Y Isomura, ... Journal of Neuroscience 34 (49), 16273-16285, 2014 | 134 | 2014 |
| Up‐regulation of GLT‐1 severely impairs LTD at mossy fibre–CA3 synapses A Omrani, M Melone, M Bellesi, V Safiulina, T Aida, K Tanaka, ... The Journal of physiology 587 (19), 4575-4588, 2009 | 104 | 2009 |
| CLICK: one-step generation of conditional knockout mice Y Miyasaka, Y Uno, K Yoshimi, Y Kunihiro, T Yoshimura, T Tanaka, ... BMC genomics 19, 1-8, 2018 | 86 | 2018 |
| Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ T Aida, S Nakade, T Sakuma, Y Izu, A Oishi, K Mochida, H Ishikubo, ... BMC genomics 17, 1-18, 2016 | 86 | 2016 |
| NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina N Bai, T Aida, M Yanagisawa, S Katou, K Sakimura, M Mishina, K Tanaka Molecular brain 6, 1-9, 2013 | 82 | 2013 |
| Laminar and subcellular heterogeneity of GLAST and GLT‐1 immunoreactivity in the developing postnatal mouse hippocampus AE Schreiner, S Durry, T Aida, MC Stock, U Rüther, K Tanaka, CR Rose, ... Journal of Comparative Neurology 522 (1), 204-224, 2014 | 63 | 2014 |
| Behavioral characterization of GLT1 (+/-) mice as a model of mild glutamatergic hyperfunction A Kiryk, T Aida, K Tanaka, P Banerjee, GM Wilczynski, K Meyza, ... Neurotoxicity research 13, 19-30, 2008 | 63 | 2008 |
| Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity N Bai, H Hayashi, T Aida, K Namekata, T Harada, M Mishina, K Tanaka Molecular Brain 6, 1-11, 2013 | 54 | 2013 |
| Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair JJ Wilde, T Aida, RCH Del Rosario, T Kaiser, P Qi, M Wienisch, Q Zhang, ... Cell 184 (12), 3267-3280. e18, 2021 | 50 | 2021 |
| Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models DS Roy, Y Zhang, T Aida, S Choi, Q Chen, Y Hou, NE Lea, KM Skaggs, ... Neuron 109 (16), 2590-2603. e13, 2021 | 47 | 2021 |
| ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk M Sekiguchi, A Sobue, I Kushima, C Wang, Y Arioka, H Kato, A Kodama, ... Translational Psychiatry 10, 247, 2020 | 44 | 2020 |
| Targeting thalamic circuits rescues motor and mood deficits in PD mice Y Zhang, DS Roy, Y Zhu, Y Chen, T Aida, Y Hou, C Shen, NE Lea, ... Nature 607 (7918), 321-329, 2022 | 43 | 2022 |
| Calpain-dependent degradation of nucleoporins contributes to motor neuron death in a mouse model of chronic excitotoxicity K Sugiyama, T Aida, M Nomura, R Takayanagi, HU Zeilhofer, K Tanaka Journal of Neuroscience 37 (36), 8830-8844, 2017 | 40 | 2017 |
| Translating human genetics into mouse: The impact of ultra‐rapid in vivo genome editing T Aida, R Imahashi, K Tanaka Development, growth & differentiation 56 (1), 34-45, 2014 | 37 | 2014 |
