Inflammatory processes in cardiovascular disease: a route to targeted therapies N Ruparelia, JT Chai, EA Fisher, RP Choudhury Nature reviews cardiology 14 (3), 133-144, 2017 | 565 | 2017 |
Anti-inflammatory effects of nicotinic acid in human monocytes are mediated by GPR109A dependent mechanisms JE Digby, F Martinez, A Jefferson, N Ruparelia, J Chai, M Wamil, ... Arteriosclerosis, thrombosis, and vascular biology 32 (3), 669-676, 2012 | 228 | 2012 |
Hyperglycemia induces trained immunity in macrophages and their precursors and promotes atherosclerosis L Edgar, N Akbar, AT Braithwaite, T Krausgruber, H Gallart-Ayala, J Bailey, ... Circulation 144 (12), 961-982, 2021 | 155 | 2021 |
Black-blood multicontrast imaging of carotid arteries with DANTE-prepared 2D and 3D MR imaging L Li, JT Chai, L Biasiolli, MD Robson, RP Choudhury, AI Handa, J Near, ... Radiology 273 (2), 560-569, 2014 | 110 | 2014 |
Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved … N Ruparelia, J Godec, R Lee, JT Chai, E Dall'Armellina, D McAndrew, ... European heart journal 36 (29), 1923-1934, 2015 | 109 | 2015 |
In-vivo quantitative T2 mapping of carotid arteries in atherosclerotic patients: segmentation and T2 measurement of plaque components L Biasiolli, AC Lindsay, JT Chai, RP Choudhury, MD Robson Journal of Cardiovascular Magnetic Resonance 15 (1), 69, 2013 | 87 | 2013 |
Quantification of Lipid-Rich Core in Carotid Atherosclerosis Using Magnetic Resonance T2 Mapping: Relation to Clinical Presentation JT Chai, L Biasiolli, L Li, M Alkhalil, F Galassi, C Darby, AW Halliday, ... JACC: Cardiovascular Imaging 10 (7), 747-756, 2017 | 82 | 2017 |
GPR109A and vascular inflammation JT Chai, JE Digby, RP Choudhury Current atherosclerosis reports 15, 1-10, 2013 | 80 | 2013 |
T2 mapping MRI technique quantifies carotid plaque lipid, and its depletion after statin initiation, following acute myocardial infarction M Alkhalil, L Biasiolli, N Akbar, F Galassi, JT Chai, MD Robson, ... Atherosclerosis 279, 100-106, 2018 | 34 | 2018 |
Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells JT Chai, JE Digby, N Ruparelia, A Jefferson, A Handa, RP Choudhury PLoS One 8 (5), e62934, 2013 | 34 | 2013 |
Differential gene expression in macrophages from human atherosclerotic plaques shows convergence on pathways implicated by genome-wide association study risk variants JT Chai, N Ruparelia, A Goel, T Kyriakou, L Biasiolli, L Edgar, A Handa, ... Arteriosclerosis, thrombosis, and vascular biology 38 (11), 2718-2730, 2018 | 29 | 2018 |
Plaque imaging to refine indications for emerging lipid-lowering drugs M Alkhalil, JT Chai, RP Choudhury European Heart Journal–Cardiovascular Pharmacotherapy 3 (1), 58-67, 2017 | 29 | 2017 |
Quantification of carotid plaque lipid content with magnetic resonance T2 mapping in patients undergoing carotid endarterectomy M Alkhalil, L Biasiolli, JT Chai, F Galassi, L Li, C Darby, A Halliday, ... PLoS One 12 (7), e0181668, 2017 | 28 | 2017 |
Cardiometabolic interventions–focus on transcriptional regulators JT Chai, RP Choudhury The European journal of cardiovascular medicine 2 (3), 212, 2013 | 6 | 2013 |
Lipid-rich Core Quantification in Carotid Atherosclerosis Using MRI T2 Mapping-Relation to Clinical Presentation and Plaque Macrophage Activation JT Chai, L Biasiolli, L Li, M Alkhalil, F Galassi, C Darby, A Halliday, ... Circulation 132 (suppl_3), A11833-A11833, 2015 | 3 | 2015 |
Histological validation of carotid plaque characterization by in-vivo T2 mapping in patients with recent cerebrovascular events: preliminary results L Biasiolli, JT Chai, L Li, A Handa, P Jezzard, R Choudhury, MD Robson Journal of Cardiovascular Magnetic Resonance 16 (1), 1-2, 2014 | 3 | 2014 |
In-vivo carotid T2 mapping can accurately quantify plaque lipid content to discriminate between symptomatic and asymptomatic patients: histological validation … L Biasiolli, JT Chai, L Li, A Handa, P Jezzard, R Choudhury, MD Robson Journal of Cardiovascular Magnetic Resonance 18, 1-3, 2016 | 2 | 2016 |
Fast three-dimensional black-blood MR imaging for carotid artery intra-plaque haemorrhage using DANTE-prepared FLASH (3D-DASH) L Li, L Biasiolli, JT Chai, MD Robson, RP Choudhury, A Handa, P Jezzard Journal of Cardiovascular Magnetic Resonance 16 (Suppl 1), O75, 2014 | 2 | 2014 |
In-vivo lipid quantification in carotid plaques using multi-slice T2 mapping: histological validation L Biasiolli, JT Chai, L Li, A Handa, P Jezzard, RP Choudhury, MD Robson Proc. of 2015 Meeting of the International Society for Magnetic Resonance in …, 2015 | 1 | 2015 |
Transvenous pacing lead‐induced superior vena cava syndrome: What do we know? RHL Wong, J Chai, CSH Ng, IYP Wan, S Wan, MJ Underwood Surgical Practice 13 (4), 125-126, 2009 | 1 | 2009 |