Spatial partitioning of the regulatory landscape of the X-inactivation centre EP Nora, BR Lajoie, EG Schulz, L Giorgetti, I Okamoto, N Servant, T Piolot, ... Nature 485 (7398), 381-385, 2012 | 3104 | 2012 |
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-γ and interleukin-12 EG Schulz, L Mariani, A Radbruch, T Höfer Immunity 30 (5), 673-683, 2009 | 400 | 2009 |
Jarid2 is implicated in the initial Xist-induced targeting of PRC2 to the inactive X chromosome ST da Rocha, V Boeva, M Escamilla-Del-Arenal, K Ancelin, C Granier, ... Molecular cell 53 (2), 301-316, 2014 | 285 | 2014 |
Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes Y Zhan, L Mariani, I Barozzi, EG Schulz, N Blüthgen, M Stadler, G Tiana, ... Genome research 27 (3), 479-490, 2017 | 202 | 2017 |
The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network EG Schulz, J Meisig, T Nakamura, I Okamoto, A Sieber, C Picard, ... Cell stem cell 14 (2), 203-216, 2014 | 191 | 2014 |
Short‐term memory in gene induction reveals the regulatory principle behind stochastic IL‐4 expression L Mariani, EG Schulz, MH Lexberg, C Helmstetter, A Radbruch, ... Molecular systems biology 6 (1), 359, 2010 | 96 | 2010 |
Direct comparison of a stable isolated Hsp70 substrate-binding domain in the empty and substrate-bound states JF Swain, EG Schulz, LM Gierasch Journal of Biological Chemistry 281 (3), 1605-1611, 2006 | 91 | 2006 |
Role and control of X chromosome dosage in mammalian development EG Schulz, E Heard Current opinion in genetics & development 23 (2), 109-115, 2013 | 90 | 2013 |
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features LBA e Sousa, I Jonkers, L Syx, I Dunkel, J Chaumeil, C Picard, B Foret, ... Genome research 29 (7), 1087-1099, 2019 | 46 | 2019 |
A symmetric toggle switch explains the onset of random X inactivation in different mammals V Mutzel, I Okamoto, I Dunkel, M Saitou, L Giorgetti, E Heard, EG Schulz Nature structural & molecular biology 26 (5), 350-360, 2019 | 44 | 2019 |
Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach O Genolet, AA Monaco, I Dunkel, M Boettcher, EG Schulz Genome Biology 22, 1-41, 2021 | 43* | 2021 |
Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus RAF Gjaltema, T Schwämmle, P Kautz, M Robson, R Schöpflin, LR Lustig, ... Molecular Cell 82 (1), 190-208. e17, 2022 | 35 | 2022 |
Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution G Pacini, I Dunkel, N Mages, V Mutzel, B Timmermann, A Marsico, ... Nature Communications 12 (1), 3638, 2021 | 29 | 2021 |
Dosage sensing, threshold responses, and epigenetic memory: a systems biology perspective on random X‐chromosome inactivation V Mutzel, EG Schulz Bioessays 42 (4), 1900163, 2020 | 28 | 2020 |
CRISPR/dCas9 switch systems for temporal transcriptional control RAF Gjaltema, EG Schulz Epigenome Editing: Methods and Protocols, 167-185, 2018 | 25 | 2018 |
X-chromosome dosage as a modulator of pluripotency, signalling and differentiation? EG Schulz Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 19 | 2017 |
CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression G Noviello, RAF Gjaltema, EG Schulz Nature Communications 14 (1), 3225, 2023 | 12 | 2023 |
Regulatory principles and mechanisms governing the onset of random X-chromosome inactivation T Schwämmle, EG Schulz Current Opinion in Genetics & Development 81, 102063, 2023 | 9 | 2023 |
Delay of human early development via in vitro diapause DP Iyer, VA Weijden, HH Khoei, A McCarthy, T Rayon, CS Simon, ... bioRxiv, 2023.05. 29.541316, 2023 | 8 | 2023 |
Dissecting molecular phenotypes through FACS-based pooled CRISPR screens O Genolet, L Ravid Lustig, EG Schulz Embryonic Stem Cell Protocols, 1-24, 2022 | 8 | 2022 |