关注
Hadi Falahatpisheh
Hadi Falahatpisheh
Vice President, ALX Oncology
在 alxoncology.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions
M Damelin, A Bankovich, J Bernstein, J Lucas, L Chen, S Williams, A Park, ...
Science translational medicine 9 (372), eaag2611, 2017
1362017
Anti-EFNA4 calicheamicin conjugates effectively target triple-negative breast and ovarian tumor-initiating cells to result in sustained tumor regressions
M Damelin, A Bankovich, A Park, J Aguilar, W Anderson, M Santaguida, ...
Clinical cancer research 21 (18), 4165-4173, 2015
782015
Liver microvascular injury and thrombocytopenia of antibody–calicheamicin conjugates in cynomolgus monkeys—mechanism and monitoring
M Guffroy, H Falahatpisheh, K Biddle, J Kreeger, L Obert, K Walters, ...
Clinical Cancer Research 23 (7), 1760-1770, 2017
512017
PF-06804103, a site-specific anti-HER2 antibody–drug conjugate for the treatment of HER2-expressing breast, gastric, and lung cancers
EI Graziani, M Sung, D Ma, B Narayanan, K Marquette, S Puthenveetil, ...
Molecular cancer therapeutics 19 (10), 2068-2078, 2020
402020
Antibody-drug conjugates as targeted therapies: Are we there yet? A critical review of the current clinical landscape
E Tarcsa, MR Guffroy, H Falahatpisheh, C Phipps, JC Kalvass
Drug Discovery Today: Technologies 37, 13-22, 2020
282020
Anti-extra domain B splice variant of fibronectin antibody–drug conjugate eliminates tumors with enhanced efficacy when combined with checkpoint blockade
AT Hooper, K Marquette, CPB Chang, J Golas, S Jain, MH Lam, M Guffroy, ...
Molecular Cancer Therapeutics 21 (9), 1462-1472, 2022
112022
Improving the safety profile of ADCs
M Guffroy, H Falahatpisheh, M Finkelstein
Innovations for next-generation antibody-drug conjugates, 45-71, 2018
62018
A PTK7-targeted antibodydrug conjugate reduces tumor-initiating cells and induces sustained tumor regressions. Sci Transl Med. 2017; 9: eaag2611
M Damelin, A Bankovich, J Bernstein, J Lucas, L Chen, S Williams, A Park, ...
5
Anatomic and clinical pathology characterization of drug-induced sinusoidal obstruction syndrome (veno-occlusive disease) in cynomolgus macaques
R Kohnken, H Falahatpisheh, KS Janardhan, M Guffroy
Toxicologic Pathology 50 (1), 13-22, 2022
42022
Next-generation DYRK1A inhibitors as a new therapeutic approach for the treatment of hematological malignancies
MC Jarvis, G Mittapalli, E Creger, C Nora, M Ibanez, D Bhat, B Hofilena, ...
Cancer Research 83 (7_Supplement), 5019-5019, 2023
22023
An anti-Ephrin-A4 calicheamicin conjugate effectively targets triple-negative breast and ovarian tumor-initiating cells to result in sustained tumor regression
M Damelin, A Bankovich, A Park, J Aguilar, W Anderson, M Santaguida, ...
Cancer Research 75 (15_Supplement), 5425-5425, 2015
12015
Abstract P250: Evaluation of systemic pan-CLK/DYRK inhibition on organ function and tissue self-renewal
H Falahatpisheh, M Dehghani, J Morrow, C Tsao, S Dorrow, J Stewart, ...
Molecular Cancer Therapeutics 20 (12_Supplement), P250-P250, 2021
2021
Development of Antibody-Drug Conjugates 1
SA Roberts, S Chivers, A Connor, H Falahatpisheh, M Guffroy, AJ Lee, ...
Translational Medicine, 277-304, 2021
2021
CAN THE HIGHEST NON-SEVERELY TOXIC DOSE FOR PYRROLOBENZODIAZEPINE-BASED ANTIBODY DRUG CONJUGATES IN CYNOMOLGUS MONKEY PREDICT HUMAN MAXIMUM-TOLERATED DOSE?.
R Menon, L Loberg, J Tibbitts, H Falahatpisheh, K Marsh, B Philip, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S48-S49, 2020
2020
Antibody-drug conjugates as targeted therapies: Are we there yet
E Tarcsa, MR Guffroy, H Falahatpisheh, C Phipps, JC Kalvass
A critical review of the current clinical landscape. Drug Discovery Today …, 2020
2020
Abstract LB-202: Liver microvascular injury and thrombocytopenia of antibody-calicheamicin conjugates: mechanism and monitoring
M Guffroy, H Falahatpisheh, K Biddle, J Kreeger, L Obert, K Walters, ...
Cancer Research 76 (14_Supplement), LB-202-LB-202, 2016
2016
A novel PTK7-targeted antibody-drug conjugate eliminates tumor-initiating cells and induces sustained tumor regressions
MI Damelin, A Bankovich, J Bernstein, J Lucas, L Chen, S Williams, ...
Cancer Research 76 (14_Supplement), 1220-1220, 2016
2016
Journal Clinical Cancer Research
M Guffroy, H Falahatpisheh, K Biddle, J Kreeger, L Obert, K Walters, ...
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