Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts RG Gieling, M Babur, L Mamnani, N Burrows, BA Telfer, F Carta, ... Journal of medicinal chemistry 55 (11), 5591-5600, 2012 | 182 | 2012 |
Expression of hypoxia-inducible factor 1α in thyroid carcinomas N Burrows, J Resch, RL Cowen, R Von Wasielewski, C Hoang-Vu, ... Endocrine-related cancer 17 (1), 61, 2010 | 135 | 2010 |
GDC-0941 inhibits metastatic characteristics of thyroid carcinomas by targeting both the phosphoinositide-3 kinase (PI3K) and hypoxia-inducible factor-1α (HIF-1α) pathways N Burrows, M Babur, J Resch, S Ridsdale, M Mejin, EJ Rowling, ... The journal of clinical endocrinology & metabolism 96 (12), E1934-E1943, 2011 | 80 | 2011 |
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors SJ Horton, G Giotopoulos, H Yun, S Vohra, O Sheppard, ... Nature cell biology 19 (9), 1093-1104, 2017 | 75 | 2017 |
Hypoxia‐inducible factor in thyroid carcinoma N Burrows, M Babur, J Resch, KJ Williams, G Brabant Journal of Thyroid Research 2011 (1), 762905, 2011 | 71 | 2011 |
Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development N Burrows, RJM Bashford-Rogers, VJ Bhute, A Penalver, JR Ferdinand, ... Nature immunology 21 (11), 1408-1420, 2020 | 63 | 2020 |
The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes BM Ortmann, N Burrows, IT Lobb, E Arnaiz, N Wit, PSJ Bailey, LH Jordon, ... Nature genetics 53 (7), 1022-1035, 2021 | 59 | 2021 |
Hypoxia and B cells N Burrows, PH Maxwell Experimental Cell Research, 2017 | 51 | 2017 |
Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20) N Burrows, G Cane, M Robson, E Gaude, W J. Howat, PW Szlosarek, ... Scientific Reports 6 (1), 22950, 2016 | 39 | 2016 |
Inhibiting the phosphatidylinositide 3-kinase pathway blocks radiation-induced metastasis associated with Rho-GTPase and Hypoxia-inducible factor-1 activity N Burrows, B Telfer, G Brabant, KJ Williams Radiotherapy and Oncology 108 (3), 548-553, 2013 | 28 | 2013 |
Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia … S Kiriakidis, SS Hoer, N Burrows, G Biddlecome, MN Khan, CC Thinnes, ... Kidney international 92 (4), 900-908, 2017 | 26 | 2017 |
Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma RS Al-Lamki, J Wang, J Yang, N Burrows, PH Maxwell, T Eisen, ... Oncotarget 7 (17), 24111, 2016 | 22 | 2016 |
The impact of hypoxia on B cells in COVID-19 P Kotagiri, F Mescia, AL Hanson, L Turner, L Bergamaschi, A Peñalver, ... EBioMedicine 77, 2022 | 20 | 2022 |
[18F]-FLT Positron Emission Tomography Can Be Used to Image the Response of Sensitive Tumors to PI3-Kinase Inhibition with the Novel Agent GDC-0941 C Cawthorne, N Burrows, RG Gieling, CJ Morrow, D Forster, J Gregory, ... Molecular cancer therapeutics 12 (5), 819-828, 2013 | 19 | 2013 |
Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas N Burrows, J Williams, BA Telfer, J Resch, HR Valentine, RJ Fitzmaurice, ... Oncotarget 7 (39), 63106, 2016 | 13 | 2016 |
The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein A Wouters, B Pauwels, N Burrows, M Baay, V Deschoolmeester, TN Vu, ... BMC cancer 14, 1-11, 2014 | 13 | 2014 |
Hypoxia-inducible factor-2 inhibitors show promise in advanced kidney cancer N Burrows, P Maxwell Nature Reviews Urology, https://doi.org/10.1038/s41585-021-00487, 2021 | 4 | 2021 |
Investigating the role of HIF-1 [alpha] in tumour growth and metastasis in an in vivo model of thyroid cancer N Burrows, J Resch, M Mejin, G Brabant, K Williams Endocrine Abstracts 21, 2010 | 1 | 2010 |
Author Correction: Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development N Burrows, RJM Bashford-Rogers, VJ Bhute, A Peñalver, JR Ferdinand, ... Nature immunology 22 (11), 1465, 2021 | | 2021 |
Dynamic regulation of hypoxia-inducible factor-1 alpha activity is essential for normal B cell development (vol 21, pg 1408, 2020) N Burrows, RJM Bashford-Rogers, VJ Bhute, A Penalver, JR Ferdinand, ... NATURE IMMUNOLOGY, 2021 | | 2021 |