S-adenosylmethionine synthesis: molecular mechanisms and clinical implications JM Mato, L Alvarez, P Ortiz, MA Pajares Pharmacology & therapeutics 73 (3), 265-280, 1997 | 644 | 1997 |
Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism? MA Pajares, D Pérez-Sala Cellular and Molecular Life Sciences CMLS 63 (23), 2792-2803, 2006 | 237 | 2006 |
S‐adenosylmethionine treatment prevents carbon tetrachloride—induced S‐adenosylmethionine synthetase inactivation and attenuates liver injury F Corrales, A Giménez, L Alvarez, J Caballería, MA Pajares, H Andreu, ... Hepatology 16 (4), 1022-1027, 1992 | 188 | 1992 |
Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione. MA Pajares, C Durán, F Corrales, MM Pliego, JM Mato Journal of Biological Chemistry 267 (25), 17598-17605, 1992 | 177 | 1992 |
Inhibition of glutathione synthesis in the liver leads to S‐adenosyl‐L‐methionine synthetase reduction F Corrales, P Ochoa, C Rivas, M Martin‐Lomas, JM Mato, MA Pajares Hepatology 14 (3), 528-533, 1991 | 162 | 1991 |
Structure-function relationships in methionine adenosyltransferases GD Markham, MA Pajares Cellular and molecular life sciences 66 (4), 636-648, 2009 | 157 | 2009 |
Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis M Gassó, M Rubio, G Varela, M Cabré, J Caballería, E Alonso, ... Journal of hepatology 25 (2), 200-205, 1996 | 138 | 1996 |
Differential expression pattern of S‐adenosylmethionine synthetase isoenzymes during rat liver development B Gil, M Casado, MA Pajares, L Bosca, JM Mato, P Martin‐Sanz, ... Hepatology 24 (4), 876-881, 1996 | 132 | 1996 |
Structural basis of protein kinase C activation by tumor promoters H Nakamura, Y Kishi, MA Pajares, RR Rando Proceedings of the National Academy of Sciences 86 (24), 9672-9676, 1989 | 132 | 1989 |
Prion protein interaction with glycosaminoglycan occurs with the formation of oligomeric complexes stabilized by Cu (II) bridges R Gonzalez-Iglesias, MA Pajares, C Ocal, JC Espinosa, B Oesch, ... Journal of molecular biology 319 (2), 527-540, 2002 | 107 | 2002 |
Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution E Reytor, J Pérez-Miguelsanz, L Alvarez, D Pérez-Sala, MA Pajares The FASEB Journal 23 (10), 3347-3360, 2009 | 101 | 2009 |
Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division S Duarte, Á Viedma-Poyatos, E Navarro-Carrasco, AE Martínez, ... Nature communications 10 (1), 4200, 2019 | 95 | 2019 |
The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site B González, MA Pajares, JA Hermoso, L Alvarez, F Garrido, JR Sufrin, ... Journal of molecular biology 300 (2), 363-375, 2000 | 87 | 2000 |
Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism R Martínez-Vega, F Garrido, T Partearroyo, R Cediel, SH Zeisel, ... The FASEB Journal 29 (2), 418-432, 2015 | 78 | 2015 |
Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism B González, MA Pajares, JA Hermoso, D Guillerm, G Guillerm, ... Journal of molecular biology 331 (2), 407-416, 2003 | 69 | 2003 |
Glucocorticoid Regulation of Hepatic S-Adenosylmethionine Synthetase Gene Expression 1 B Gil, MA Pajares, JM Mato, L Alvarez Endocrinology 138 (3), 1251-1258, 1997 | 68 | 1997 |
Inactivation and dissociation of s‐adenosylmethionine synthetase by modification of sulfhydryl groups and its possile occurrence in cirrhosis F Corrales, C Cabrero, MA Pajares, P Ortiz, A Martin‐Duce, JM Mato Hepatology 11 (2), 216-222, 1990 | 65 | 1990 |
Methionine adenosyltransferase (S-adenosylmethionine synthetase) MA Pajares, GD Markham Advances in enzymology and related areas of molecular biology 78, 449, 2011 | 61 | 2011 |
Methionine adenosyltransferase as a useful molecular systematics tool revealed by phylogenetic and structural analyses GF Sánchez-Pérez, JM Bautista, MA Pajares Journal of molecular biology 335 (3), 693-706, 2004 | 61 | 2004 |
Site-directed mutagenesis of rat liver S-adenosylmethionine synthetase. Identification of a cysteine residue critical for the oligomeric state J Mingorance, L Álvarez, E Sánchez-Góngora, JM Mato, MA Pajares Biochemical Journal 315 (3), 761-766, 1996 | 60 | 1996 |