| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13277* | 2021 |
| The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease YH Youm, KY Nguyen, RW Grant, EL Goldberg, M Bodogai, D Kim, ... Nature medicine 21 (3), 263-269, 2015 | 1800 | 2015 |
| Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases SM Man, R Karki, TD Kanneganti Immunological reviews 277 (1), 61-75, 2017 | 1413 | 2017 |
| Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages L Franchi, A Amer, M Body-Malapel, TD Kanneganti, N Özören, ... Nature immunology 7 (6), 576-582, 2006 | 1374 | 2006 |
| Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 TD Kanneganti, N Özören, M Body-Malapel, A Amer, JH Park, L Franchi, ... Nature 440 (7081), 233-236, 2006 | 1330 | 2006 |
| Intracellular NOD-like receptors in host defense and disease TD Kanneganti, M Lamkanfi, G Núñez Immunity 27 (4), 549-559, 2007 | 1298 | 2007 |
| Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1144 | 2021 |
| The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis MH Zaki, KL Boyd, P Vogel, MB Kastan, M Lamkanfi, TD Kanneganti Immunity 32 (3), 379-391, 2010 | 1052 | 2010 |
| Regulation of inflammasome activation SM Man, TD Kanneganti Immunological reviews 265 (1), 6-21, 2015 | 1021 | 2015 |
| Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA TD Kanneganti, M Body-Malapel, A Amer, JH Park, J Whitfield, L Franchi, ... Journal of Biological Chemistry 281 (48), 36560-36568, 2006 | 826 | 2006 |
| RETRACTED ARTICLE: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins J Martinez, RKS Malireddi, Q Lu, LD Cunha, S Pelletier, S Gingras, ... Nature cell biology 17 (7), 893-906, 2015 | 824 | 2015 |
| The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1 PG Thomas, P Dash, JR Aldridge, AH Ellebedy, C Reynolds, AJ Funk, ... Immunity 30 (4), 566-575, 2009 | 812 | 2009 |
| Inflammasome is a central player in the induction of obesity and insulin resistance R Stienstra, JA Van Diepen, CJ Tack, MH Zaki, FL Van De Veerdonk, ... Proceedings of the National Academy of Sciences 108 (37), 15324-15329, 2011 | 778 | 2011 |
| Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens KC El Kasmi, JE Qualls, JT Pesce, AM Smith, RW Thompson, ... Nature immunology 9 (12), 1399-1406, 2008 | 745 | 2008 |
| The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation D Sharma, TD Kanneganti Journal of Cell Biology 213 (6), 617-629, 2016 | 713 | 2016 |
| The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity R Stienstra, LAB Joosten, T Koenen, B Van Tits, JA Van Diepen, ... Cell metabolism 12 (6), 593-605, 2010 | 691 | 2010 |
| Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling TD Kanneganti, M Lamkanfi, YG Kim, G Chen, JH Park, L Franchi, ... Immunity 26 (4), 433-443, 2007 | 674 | 2007 |
| RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs JH Park, YG Kim, C McDonald, TD Kanneganti, M Hasegawa, ... The Journal of Immunology 178 (4), 2380-2386, 2007 | 630 | 2007 |
| Converging roles of caspases in inflammasome activation, cell death and innate immunity SM Man, TD Kanneganti Nature Reviews Immunology 16 (1), 7-21, 2016 | 628 | 2016 |
| Caspases in cell death, inflammation, and pyroptosis S Kesavardhana, RKS Malireddi, TD Kanneganti Annual review of immunology 38, 567-595, 2020 | 588 | 2020 |
