MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells H Zirath, A Frenzel, G Oliynyk, L Segerström, UK Westermark, K Larsson, ... Proceedings of the National Academy of Sciences 110 (25), 10258-10263, 2013 | 244 | 2013 |
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma J Buechner, E Tømte, BH Haug, JR Henriksen, C Løkke, T Flægstad, ... British journal of cancer 105 (2), 296-303, 2011 | 233 | 2011 |
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance M Wickström, C Dyberg, J Milosevic, C Einvik, R Calero, ... Nature communications 6 (1), 8904, 2015 | 219 | 2015 |
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma BH Haug, JR Henriksen, J Buechner, D Geerts, E Tømte, P Kogner, ... Carcinogenesis 32 (7), 1005-1012, 2011 | 92 | 2011 |
N-myc and noncoding RNAs in neuroblastoma J Buechner, C Einvik Molecular cancer research 10 (10), 1243-1253, 2012 | 84 | 2012 |
The ability to form full-length intron RNA circles is a general property of nuclear group I introns H Nielsen, T Fiskaa, ÅSAB BIRGISDOTTIR, P Haugen, C Einvik, ... RNA 9 (12), 1464-1475, 2003 | 73 | 2003 |
Two group I ribozymes with different functions in a nuclear rDNA intron. WA Decatur, C Einvik, S Johansen, VM Vogt The EMBO Journal 14 (18), 4558-4568, 1995 | 62 | 1995 |
Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma ØH Hald, L Olsen, G Gallo-Oller, LHM Elfman, C Løkke, P Kogner, ... Oncogene 38 (15), 2800-2813, 2019 | 56 | 2019 |
Exosome-like extracellular vesicles from MYCN-amplified neuroblastoma cells contain oncogenic miRNAs BH Haug, ØH Hald, P Utnes, SA Roth, C Løkke, T Flaegstad, C Einvik Anticancer research 35 (5), 2521-2530, 2015 | 54 | 2015 |
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines JR Henriksen, C Løkke, M Hammerø, D Geerts, R Versteeg, T Flægstad, ... Nucleic acids research 35 (9), e67, 2007 | 52 | 2007 |
Group I twintrons: genetic elements in myxomycete and schizopyrenid amoeboflagellate ribosomal DNAs C Einvik, M Elde, S Johansen Journal of biotechnology 64 (1), 63-74, 1998 | 51 | 1998 |
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma JR Henriksen, BH Haug, J Buechner, E Tømte, C Løkke, T Flaegstad, ... BMC developmental biology 11, 1-11, 2011 | 49 | 2011 |
Group I-like ribozymes with a novel core organization perform obligate sequential hydrolytic cleavages at two processing sites. C Einvik, H Nielsen, E Westhof, F Michel, S Johansen RNA 4 (5), 530-541, 1998 | 48 | 1998 |
Naegleria nucleolar introns contain two group I ribozymes with different functions in RNA splicing and processing. C Einvik, WA Decatur, TM Embley, VM Vogt, S Johansen Rna 3 (7), 710-720, 1997 | 48 | 1997 |
Twelve Group I Introns in the Same Pre-rRNA Transcript of the Myxomycete Fuligo septica: RNA Processing and Evolution EW Lundblad, C Einvik, S Rønning, K Haugli, S Johansen Molecular Biology and Evolution 21 (7), 1283-1293, 2004 | 42 | 2004 |
Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron OG Wikmark, C Einvik, JF De Jonckheere, SD Johansen BMC evolutionary biology 6, 1-12, 2006 | 40 | 2006 |
MicroRNA-193b-3p represses neuroblastoma cell growth via downregulation of Cyclin D1, MCL-1 and MYCN SA Roth, ØH Hald, S Fuchs, C Løkke, I Mikkola, T Flægstad, J Schulte, ... Oncotarget 9 (26), 18160, 2018 | 38 | 2018 |
Clinically relevant biomarker discovery in high-risk recurrent neuroblastoma P Utnes, C Løkke, T Flægstad, C Einvik Cancer informatics 18, 1176935119832910, 2019 | 37 | 2019 |
Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells J Buechner, JR Henriksen, BH Haug, E Tømte, T Flaegstad, C Einvik Differentiation 81 (1), 25-34, 2011 | 37 | 2011 |
DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role S Johansen, C Einvik, H Nielsen Biochimie 84 (9), 905-912, 2002 | 35 | 2002 |