Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains A Müller, M Wenzel, H Strahl, F Grein, TNV Saaki, B Kohl, T Siersma, ... Proceedings of the National Academy of Sciences 113 (45), E7077-E7086, 2016 | 422 | 2016 |
Small cationic antimicrobial peptides delocalize peripheral membrane proteins M Wenzel, AI Chiriac, A Otto, D Zweytick, C May, C Schumacher, R Gust, ... Proceedings of the National Academy of Sciences 111 (14), E1409-E1418, 2014 | 330 | 2014 |
Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics M Wenzel, M Patra, CHR Senges, I Ott, JJ Stepanek, A Pinto, P Prochnow, ... ACS chemical biology 8 (7), 1442-1450, 2013 | 147 | 2013 |
Multitarget approaches against multiresistant superbugs DA Gray, M Wenzel ACS Infectious Diseases 6 (6), 1346-1365, 2020 | 143 | 2020 |
Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane M Wenzel, B Kohl, D Münch, N Raatschen, HB Albada, L Hamoen, ... Antimicrobial agents and chemotherapy 56 (11), 5749-5757, 2012 | 117 | 2012 |
Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis K Scheinpflug, M Wenzel, O Krylova, JE Bandow, M Dathe, H Strahl Scientific reports 7 (1), 44332, 2017 | 109 | 2017 |
Synthesis and biological evaluation of ferrocene-containing bioorganometallics inspired by the antibiotic platensimycin lead structure M Patra, G Gasser, M Wenzel, K Merz, JE Bandow, N Metzler-Nolte Organometallics 29 (19), 4312-4319, 2010 | 106 | 2010 |
The multifaceted antibacterial mechanisms of the pioneering peptide antibiotics tyrocidine and gramicidin S M Wenzel, M Rautenbach, JA Vosloo, T Siersma, CHM Aisenbrey, ... MBio 9 (5), 10.1128/mbio. 00802-18, 2018 | 105 | 2018 |
More than a pore: a current perspective on the in vivo mode of action of the lipopeptide antibiotic daptomycin DA Gray, M Wenzel Antibiotics 9 (1), 17, 2020 | 101 | 2020 |
The lantibiotic NAI-107 binds to bactoprenol-bound cell wall precursors and impairs membrane functions D Münch, A Müller, T Schneider, B Kohl, M Wenzel, JE Bandow, S Maffioli, ... Journal of Biological Chemistry 289 (17), 12063-12076, 2014 | 95 | 2014 |
Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups HB Albada, AI Chiriac, M Wenzel, M Penkova, JE Bandow, HG Sahl, ... Beilstein journal of organic chemistry 8 (1), 1753-1764, 2012 | 84 | 2012 |
Bactericidal activity of amphipathic cationic antimicrobial peptides involves altering the membrane fluidity when interacting with the phospholipid bilayer S Omardien, JW Drijfhout, FM Vaz, M Wenzel, LW Hamoen, SAJ Zaat, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (11), 2404-2415, 2018 | 78 | 2018 |
An organometallic structure-activity relationship study reveals the essential role of a Re (CO) 3 moiety in the activity against gram-positive pathogens including MRSA M Patra, M Wenzel, P Prochnow, V Pierroz, G Gasser, JE Bandow, ... Chemical science 6 (1), 214-224, 2015 | 76 | 2015 |
The novel antibiotic rhodomyrtone traps membrane proteins in vesicles with increased fluidity D Saeloh, V Tipmanee, KK Jim, MP Dekker, W Bitter, ... PLoS pathogens 14 (2), e1006876, 2018 | 75 | 2018 |
Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies M Wenzel, M Patra, D Albrecht, DYK Chen, KC Nicolaou, N Metzler-Nolte, ... Antimicrobial agents and chemotherapy 55 (6), 2590-2596, 2011 | 74 | 2011 |
Proteomic signatures in antibiotic research M Wenzel, JE Bandow Proteomics 11 (15), 3256-3268, 2011 | 68 | 2011 |
A how-to guide for mode of action analysis of antimicrobial peptides AB Schäfer, M Wenzel Frontiers in cellular and infection microbiology 10, 540898, 2020 | 53 | 2020 |
Assessing membrane fluidity and visualizing fluid membrane domains in bacteria using fluorescent membrane dyes M Wenzel, NOE Vischer, H Strahl, LW Hamoen Bio-protocol 8 (20), e3063-e3063, 2018 | 53 | 2018 |
Sandwich and half-sandwich derivatives of Platensimycin: Synthesis and biological evaluation M Patra, G Gasser, M Wenzel, K Merz, JE Bandow, N Metzler-Nolte Organometallics 31 (16), 5760-5771, 2012 | 49 | 2012 |
Influence of lipidation on the mode of action of a small RW-rich antimicrobial peptide M Wenzel, P Schriek, P Prochnow, HB Albada, N Metzler-Nolte, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (5), 1004-1011, 2016 | 48 | 2016 |