Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity F Borges, F Roleira, N Milhazes, L Santana, E Uriarte Current medicinal chemistry 12 (8), 887-916, 2005 | 1221 | 2005 |
Medicinal chemistry and bioinformatics-current trends in drugs discovery with networks topological indices H Gonzalez-Diaz, S Vilar, L Santana, E Uriarte Current topics in medicinal chemistry 7 (10), 1015-1029, 2007 | 377 | 2007 |
Proteomics, networks and connectivity indices H González‐Díaz, Y González‐Díaz, L Santana, FM Ubeira, E Uriarte Proteomics 8 (4), 750-778, 2008 | 308 | 2008 |
Coumarins—an important class of phytochemicals MJ Matos, L Santana, E Uriarte, OA Abreu, E Molina, EG Yordi Phytochemicals-isolation, characterisation and role in human health 25, 533-538, 2015 | 260 | 2015 |
Drug—drug interaction through molecular structure similarity analysis S Vilar, R Harpaz, E Uriarte, L Santana, R Rabadan, C Friedman Journal of the American Medical Informatics Association 19 (6), 1066-1074, 2012 | 239 | 2012 |
Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity L Santana, E Uriarte, F Roleira, N Milhazes, F Borges Current medicinal chemistry 11 (24), 3239-3261, 2004 | 231 | 2004 |
Similarity-based modeling in large-scale prediction of drug-drug interactions S Vilar, E Uriarte, L Santana, T Lorberbaum, G Hripcsak, C Friedman, ... Nature protocols 9 (9), 2147-2163, 2014 | 229 | 2014 |
A novel approach for the virtual screening and rational design of anticancer compounds E Estrada, E Uriarte, A Montero, M Teijeira, L Santana, E De Clercq Journal of medicinal chemistry 43 (10), 1975-1985, 2000 | 223 | 2000 |
Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin–resveratrol hybrids S Vilar, E Quezada, L Santana, E Uriarte, M Yánez, N Fraiz, C Alcaide, ... Bioorganic & Medicinal Chemistry Letters 16 (2), 257-261, 2006 | 204 | 2006 |
A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins L Santana, E Uriarte, H González-Díaz, G Zagotto, R Soto-Otero, ... Journal of medicinal chemistry 49 (3), 1149-1156, 2006 | 190 | 2006 |
Potential pharmacological uses of chalcones: a patent review (from June 2011–2014) MJ Matos, S Vazquez-Rodriguez, E Uriarte, L Santana Expert opinion on therapeutic patents 25 (3), 351-366, 2015 | 173 | 2015 |
Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors MJ Matos, C Teran, Y Perez-Castillo, E Uriarte, L Santana, D Vina Journal of medicinal chemistry 54 (20), 7127-7137, 2011 | 170 | 2011 |
A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors MJ Matos, D Viña, E Quezada, C Picciau, G Delogu, F Orallo, L Santana, ... Bioorganic & medicinal chemistry letters 19 (12), 3268-3270, 2009 | 157 | 2009 |
Quantitative structure− activity relationship and complex network approach to monoamine oxidase A and B inhibitors L Santana, H Gonzalez-Diaz, E Quezada, E Uriarte, M Yanez, D Vina, ... Journal of medicinal chemistry 51 (21), 6740-6751, 2008 | 145 | 2008 |
Simple coumarins: privileged scaffolds in medicinal chemistry MFM Borges, FMF Roleira, N Milhazes, EU Villare, LS Penin Frontiers in medicinal chemistry 4, 23-85, 2010 | 140 | 2010 |
Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors MJ Matos, D Viña, C Picciau, F Orallo, L Santana, E Uriarte Bioorganic & medicinal chemistry letters 19 (17), 5053-5055, 2009 | 133 | 2009 |
Detection of drug-drug interactions by modeling interaction profile fingerprints S Vilar, E Uriarte, L Santana, NP Tatonetti, C Friedman PloS one 8 (3), e58321, 2013 | 129 | 2013 |
3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease D Vina, MJ Matos, M Yáñez, L Santana, E Uriarte MedChemComm 3 (2), 213-218, 2012 | 124 | 2012 |
Trending topics on coumarin and its derivatives in 2020 A Carneiro, MJ Matos, E Uriarte, L Santana Molecules 26 (2), 501, 2021 | 119 | 2021 |
Synthesis and vasorelaxant activity of new coumarin and furocoumarin derivatives M Campos-Toimil, F Orallo, L Santana, E Uriarte Bioorganic & medicinal chemistry letters 12 (5), 783-786, 2002 | 117 | 2002 |