| Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ... Nature cell biology 20 (3), 285-295, 2018 | 1445 | 2018 |
| METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 713 | 2018 |
| R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ... Cell 172 (1-2), 90-105. e23, 2018 | 712 | 2018 |
| RNA N6-methyladenosine modification in cancers: current status and perspectives X Deng, R Su, H Weng, H Huang, Z Li, J Chen Cell research 28 (5), 507-517, 2018 | 499 | 2018 |
| Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ... Nature 567 (7748), 414-419, 2019 | 400 | 2019 |
| Targeting FTO suppresses cancer stem cell maintenance and immune evasion R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ... Cancer cell 38 (1), 79-96. e11, 2020 | 327 | 2020 |
| RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ... Cell stem cell 27 (1), 64-80. e9, 2020 | 204 | 2020 |
| Role of N6-methyladenosine modification in cancer X Deng, R Su, X Feng, M Wei, J Chen Current opinion in genetics & development 48, 1-7, 2018 | 172 | 2018 |
| R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ... Molecular cell 81 (5), 922-939. e9, 2021 | 132 | 2021 |
| Critical enzymatic functions of FTO in obesity and cancer X Deng, R Su, S Stanford, J Chen Frontiers in endocrinology 9, 396, 2018 | 101 | 2018 |
| METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ... Nature cell biology 24 (2), 205-216, 2022 | 81 | 2022 |
| Cancer precision medicine: from cancer screening to drug selection and personalized immunotherapy X Deng, Y Nakamura Trends in pharmacological sciences 38 (1), 15-24, 2017 | 81 | 2017 |
| RNA modifications in cancer: functions, mechanisms, and therapeutic implications H Huang, H Weng, X Deng, J Chen Annual Review of Cancer Biology 4, 221-240, 2020 | 51 | 2020 |
| Impact of temperature exposure on stability of drugs in a real-world out-of-hospital setting S De Winter, P Vanbrabant, NTT Vi, X Deng, I Spriet, A Van Schepdael, ... Annals of emergency medicine 62 (4), 380-387. e1, 2013 | 51 | 2013 |
| Critical roles of SMYD2-mediated β-catenin methylation for nuclear translocation and activation of Wnt signaling X Deng, R Hamamoto, T Vougiouklakis, R Wang, Y Yoshioka, T Suzuki, ... Oncotarget 8 (34), 55837, 2017 | 40 | 2017 |
| Effects of SMYD 2‐mediated EML 4‐ALK methylation on the signaling pathway and growth in non‐small‐cell lung cancer cells R Wang, X Deng, Y Yoshioka, T Vougiouklakis, JH Park, T Suzuki, ... Cancer Science 108 (6), 1203-1209, 2017 | 40 | 2017 |
| WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer V Saloura, T Vougiouklakis, M Zewde, X Deng, K Kiyotani, JH Park, ... Scientific reports 7 (1), 1-13, 2017 | 39 | 2017 |
| Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, ... haematologica 105 (1), 148, 2020 | 38 | 2020 |
| Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin M He, H Wu, Q Jiang, Y Liu, L Han, Y Yan, B Wei, F Liu, X Deng, H Chen, ... Molecular oncology 13 (2), 403-421, 2019 | 37 | 2019 |
| PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP X Deng, G Von Keudell, T Suzuki, N Dohmae, M Nakakido, L Piao, ... Oncotarget 6 (34), 35173, 2015 | 29 | 2015 |
Yusuke NakamuraJFCR, University of Chicago, University of Tokyo, RIKEN, Cancer Institute, Univ. of Utah, Osaka Univ在 jfcr.or.jp 的电子邮件经过验证
