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Xiaolan Deng
Xiaolan Deng
City of Hope, Beckman Research Institute, Department of System Biology
在 coh.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ...
Nature cell biology 20 (3), 285-295, 2018
20402018
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling
R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ...
Cell 172 (1), 90-105. e23, 2018
8842018
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification
H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ...
Cell stem cell 22 (2), 191-205. e9, 2018
8322018
RNA N6-methyladenosine modification in cancers: current status and perspectives
X Deng, R Su, H Weng, H Huang, Z Li, J Chen
Cell research 28 (5), 507-517, 2018
6122018
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ...
Nature 567 (7748), 414-419, 2019
5122019
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer cell 38 (1), 79-96. e11, 2020
4732020
RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia
C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ...
Cell stem cell 27 (1), 64-80. e9, 2020
2792020
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ...
Molecular cell 81 (5), 922-939. e9, 2021
2022021
Role of N6-methyladenosine modification in cancer
X Deng, R Su, X Feng, M Wei, J Chen
Current opinion in genetics & development 48, 1-7, 2018
1972018
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ...
Nature cell biology 24 (2), 205-216, 2022
1732022
Critical enzymatic functions of FTO in obesity and cancer
X Deng, R Su, S Stanford, J Chen
Frontiers in endocrinology 9, 396, 2018
1202018
Cancer precision medicine: from cancer screening to drug selection and personalized immunotherapy
X Deng, Y Nakamura
Trends in pharmacological sciences 38 (1), 15-24, 2017
922017
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
H Weng, F Huang, Z Yu, Z Chen, E Prince, Y Kang, K Zhou, W Li, J Hu, ...
Cancer Cell 40 (12), 1566-1582. e10, 2022
912022
FTO in cancer: functions, molecular mechanisms, and therapeutic implications
Y Li, R Su, X Deng, Y Chen, J Chen
Trends in cancer 8 (7), 598-614, 2022
862022
RNA modifications in cancer: functions, mechanisms, and therapeutic implications
H Huang, H Weng, X Deng, J Chen
Annual Review of Cancer Biology 4, 221-240, 2020
722020
The roles and implications of RNA m6A modification in cancer
X Deng, Y Qing, D Horne, H Huang, J Chen
Nature Reviews Clinical Oncology 20 (8), 507-526, 2023
652023
Impact of temperature exposure on stability of drugs in a real-world out-of-hospital setting
S De Winter, P Vanbrabant, NTT Vi, X Deng, I Spriet, A Van Schepdael, ...
Annals of emergency medicine 62 (4), 380-387. e1, 2013
602013
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, ...
haematologica 105 (1), 148, 2020
502020
Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin
M He, H Wu, Q Jiang, Y Liu, L Han, Y Yan, B Wei, F Liu, X Deng, H Chen, ...
Molecular oncology 13 (2), 403-421, 2019
472019
Effects of SMYD 2‐mediated EML 4‐ALK methylation on the signaling pathway and growth in non‐small‐cell lung cancer cells
R Wang, X Deng, Y Yoshioka, T Vougiouklakis, JH Park, T Suzuki, ...
Cancer Science 108 (6), 1203-1209, 2017
472017
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