Understanding anomalous mobility of proteins on SDS-PAGE with special reference to the highly acidic extracellular domains of human E- and N-cadherins PG Prince Tiwari 1, Pallavi Kaila 1 Electrophoresis, 2019 | 36 | 2019 |
Multiple thermostable enzyme hydrolases on magnetic nanoparticles: An immobilized enzyme-mediated approach to saccharification through simultaneous xylanase, cellulase and … A Kumari, P Kaila, P Tiwari, V Singh, S Kaul, N Singhal, P Guptasarma International journal of biological macromolecules 120, 1650-1658, 2018 | 35 | 2018 |
The Achilles’ Heel of “Ultrastable” hyperthermophile proteins: submillimolar concentrations of SDS stimulate rapid conformational change, aggregation, and amyloid formation in … JM Khan, P Sharma, K Arora, N Kishor, P Kaila, P Guptasarma Biochemistry 55 (28), 3920-3936, 2016 | 31 | 2016 |
Structural-mechanical and biochemical functions of classical cadherins at cellular junctions: a review and some hypotheses P Tiwari, A Mrigwani, H Kaur, P Kaila, R Kumar, P Guptasarma Biochemical and Biophysical Roles of Cell Surface Molecules, 107-138, 2018 | 25 | 2018 |
Kinase domain is a dynamic hub for driving LRRK2 allostery SS Taylor, P Kaila-Sharma, JH Weng, P Aoto, SH Schmidt, S Knapp, ... Frontiers in molecular neuroscience 13, 538219, 2020 | 21 | 2020 |
LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains JH Weng, PC Aoto, R Lorenz, J Wu, SH Schmidt, JT Manschwetus, ... PLoS biology 20 (2), e3001427, 2022 | 19 | 2022 |
Capturing differences in the regulation of LRRK2 dynamics and conformational states by small molecule kinase inhibitors JH Weng, W Ma, J Wu, PK Sharma, S Silletti, JA McCammon, S Taylor ACS chemical biology 18 (4), 810-821, 2023 | 16 | 2023 |
Creation of active TIM barrel enzymes through genetic fusion of half‐barrel domain constructs derived from two distantly related glycosyl hydrolases P Sharma, P Kaila, P Guptasarma The FEBS journal 283 (23), 4340-4356, 2016 | 14 | 2016 |
Novel LRR-ROC motif that links the N-and C-terminal domains in LRRK2 undergoes an order–disorder transition upon activation JH Weng, CR Trilling, PK Sharma, E Störmer, J Wu, FW Herberg, ... Journal of molecular biology 435 (12), 167999, 2023 | 12 | 2023 |
An ultra-stable glucanotransferase-cum-exoamylase from the hyperthermophile archaeon Thermococcus onnurineus. GP Kaila P Arch Biochem Biophys 665, 114-121, 2019 | 7 | 2019 |
Structure-guided mutational evidence and postulates explaining how a glycohydrolase from Pyrococcus furiosus functions simultaneously as an amylase and as a 4-α-glucanotransferase P Kaila, GS Mehta, N Dhaunta, P Guptasarma Biochemical and biophysical research communications 509 (4), 892-897, 2019 | 5 | 2019 |
Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW E Störmer, JH Weng, J Wu, D Bertinetti, P Kaila Sharma, W Ma, ... Biochemical Journal 480 (11), 815-833, 2023 | 4 | 2023 |
RedOx regulation of LRRK2 kinase activity by active site cysteines CR Trilling, JH Weng, PK Sharma, V Nolte, J Wu, W Ma, D Boassa, ... npj Parkinson's Disease 10 (1), 75, 2024 | 3 | 2024 |
Corrigendum to" Novel LRR-ROC Motif That Links the N-and C-terminal Domains in LRRK2 Undergoes an Order-Disorder Transition Upon Activation"[J. Mol. Biol. 435 (12)(2023) 1-17] JH Weng, CR Trilling, PK Sharma, E Störmer, J Wu, FW Herberg, ... Journal of molecular biology 436 (6), 168485, 2024 | | 2024 |
Role of the leucine-rich repeat protein kinase 2 C-terminal tail in domain cross-talk PK Sharma, JH Weng, JT Manschwetus, J Wu, W Ma, FW Herberg, ... Biochemical Journal 481 (4), 313-327, 2024 | | 2024 |
Differences in the activities of domain-swapped chimeras of two homologous GH57 glucanotransferases suggest that a glucan-binding DUF could influence donor substrate specificity A Sarkar, P Kaila, P Guptasarma bioRxiv, 2023.08. 25.554918, 2023 | | 2023 |
A glucanotransferase that uses two sub-sites and four catalytic aspartates/glutamates to disproportionate oligosaccharides ranging in length from maltotriose to starch A Sarkar, P Kaila, P Tiwari, P Guptasarma bioRxiv, 2023.08. 25.554913, 2023 | | 2023 |
Exploring the novel mechanistic aspects of function of a hyperthermophile two-site exo-amylase-cum-glucanotransferase displaying substrate versatility A Sarkar, PK Sharma, P Guptasarma Biophysical Journal 121 (3), 346a, 2022 | | 2022 |