| Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor V Münch, L Trentin, J Herzig, S Demir, F Seyfried, JM Kraus, HA Kestler, ... Blood, The Journal of the American Society of Hematology 130 (5), 643-654, 2017 | 89 | 2017 |
| Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition S Köhrer, O Havranek, F Seyfried, C Hurtz, GP Coffey, E Kim, ... Leukemia 30 (6), 1246-1254, 2016 | 81 | 2016 |
| Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling F Seyfried, S Demir, RL Hörl, FU Stirnweiß, J Ryan, A Scheffold, ... Cell death & disease 10 (8), 571, 2019 | 48 | 2019 |
| IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia A Alsadeq, L Lenk, A Vadakumchery, A Cousins, C Vokuhl, A Khadour, ... Blood, The Journal of the American Society of Hematology 132 (15), 1614-1617, 2018 | 42 | 2018 |
| Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia M Schirmer, L Trentin, M Queudeville, F Seyfried, S Demir, E Tausch, ... Cell death & disease 7 (1), e2052-e2052, 2016 | 36 | 2016 |
| Tight regulation of FOXO1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia F Wang, S Demir, F Gehringer, CD Osswald, F Seyfried, S Enzenmüller, ... Blood, The Journal of the American Society of Hematology 131 (26), 2929-2942, 2018 | 35 | 2018 |
| Rapid engraftment of human ALL in NOD/SCID mice involves deficient apoptosis signaling M Queudeville, F Seyfried, SM Eckhoff, L Trentin, S Ulrich, M Schirmer, ... Cell death & disease 3 (8), e364-e364, 2012 | 28 | 2012 |
| MicroRNA-497/195 is tumor suppressive and cooperates with CDKN2A/B in pediatric acute lymphoblastic leukemia E Boldrin, E Gaffo, A Niedermayer, JM Boer, M Zimmermann, ... Blood, The Journal of the American Society of Hematology 138 (20), 1953-1965, 2021 | 26 | 2021 |
| Evaluation of vecabrutinib as a model for noncovalent BTK/ITK inhibition for treatment of chronic lymphocytic leukemia BMC Jebaraj, A Müller, RP Dheenadayalan, S Endres, PM Roessner, ... Blood, The Journal of the American Society of Hematology 139 (6), 859-875, 2022 | 24 | 2022 |
| Synergistic activity of combined inhibition of anti-apoptotic molecules in B-cell precursor ALL F Seyfried, FU Stirnweiß, A Niedermayer, S Enzenmüller, RL Hörl, ... Leukemia 36 (4), 901-912, 2022 | 15 | 2022 |
| Leukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state L Trentin, M Queudeville, SM Eckhoff, N Hasan, V Münch, E Boldrin, ... haematologica 103 (6), 1008, 2018 | 9 | 2018 |
| MCL-1 inhibition overcomes anti-apoptotic adaptation to targeted therapies in B-cell precursor acute lymphoblastic leukemia A Manzano-Muñoz, C Alcon, P Menéndez, M Ramírez, F Seyfried, ... Frontiers in Cell and Developmental Biology 9, 695225, 2021 | 8 | 2021 |
| Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation J Lázaro-Navarro, HJ Pimentel-Gutiérrez, A Gauert, AIH Hagemann, ... Blood Advances 5 (24), 5501-5506, 2021 | 5 | 2021 |
| Venetoclax Resistance in Mantle Cell Lymphoma Is Mediated By BCL-XL and Can be Circumvent By Inhibiting the BH4 Domain of BCL-2 D Steinbrecher, F Seyfried, E Tausch, J Bloehdorn, BMC Jebaraj, ... Blood 134, 1507, 2019 | 2 | 2019 |
| Synergistic Activity of ABT-199 with Conventional Chemotherapy and Dinaciclib in B-Cell Precursor Acute Lymphoblastic Leukemia F Seyfried, S Demir, KM Debatin, LH Meyer Blood 126 (23), 2631, 2015 | 2 | 2015 |
| Venetoclax resistance in acute lymphoblastic leukemia is characterized by increased mitochondrial activity and can be overcome by co-targeting oxidative phosphorylation S Enzenmüller, A Niedermayer, F Seyfried, V Muench, D Tews, U Rupp, ... Cell Death & Disease 15 (7), 475, 2024 | 1 | 2024 |
| Acquired Venetoclax Resistance in an In Vivo Model of B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By Altered Functions of Apoptosis Regulators S Enzenmüller, A Niedermayer, F Seyfried, A Groß, KM Debatin, ... Blood 142, 1446, 2023 | 1 | 2023 |
| Venetoclax Resistance in B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By Increased Mitochondrial Metabolism and Can be Overcome By Co-Targeting Oxidative … A Niedermayer, S Enzenmüller, F Seyfried, D Tews, P Fischer-Posovszky, ... Blood 140 (Supplement 1), 6358-6359, 2022 | 1 | 2022 |
| Synergistic activity of BH3-mimetics by combined targeting of anti-apoptotic regulators in B-cell precursor ALL F Seyfried, F Stirnweiß, A Niedermayer, S Enzenmüller, R Hörl, S Köhrer, ... Blood 138, 706, 2021 | 1 | 2021 |
| Synergistic Activity of the MCL-1-Specific Inhibitor S63845 with Venetoclax in B-Cell Precursor Acute Lymphoblastic Leukemia F Seyfried, F Stirnweiß, S Köhrer, KM Debatin, LH Meyer Blood 132, 1416, 2018 | 1 | 2018 |
