TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β JC Kagan, T Su, T Horng, A Chow, S Akira, R Medzhitov Nature immunology 9 (4), 361-368, 2008 | 1515 | 2008 |
Innate immune pattern recognition: a cell biological perspective SW Brubaker, KS Bonham, I Zanoni, JC Kagan Annual review of immunology 33, 257-290, 2015 | 1424 | 2015 |
Toll-like receptors and the control of immunity KA Fitzgerald, JC Kagan Cell 180 (6), 1044-1066, 2020 | 1023 | 2020 |
CD14 controls the LPS-induced endocytosis of Toll-like receptor 4 I Zanoni, R Ostuni, LR Marek, S Barresi, R Barbalat, GM Barton, ... Cell 147 (4), 868-880, 2011 | 1011 | 2011 |
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling JC Kagan, R Medzhitov Cell 125 (5), 943-955, 2006 | 996 | 2006 |
A cell biological view of Toll-like receptor function: regulation through compartmentalization GM Barton, JC Kagan Nature Reviews Immunology 9 (8), 535-542, 2009 | 892 | 2009 |
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA GM Barton, JC Kagan, R Medzhitov Nature immunology 7 (1), 49-56, 2006 | 885 | 2006 |
Peroxisomes are signaling platforms for antiviral innate immunity E Dixit, S Boulant, Y Zhang, ASY Lee, C Odendall, B Shum, N Hacohen, ... Cell 141 (4), 668-681, 2010 | 860 | 2010 |
The pore-forming protein gasdermin D regulates interleukin-1 secretion from living macrophages CL Evavold, J Ruan, Y Tan, S Xia, H Wu, JC Kagan Immunity 48 (1), 35-44. e6, 2018 | 834 | 2018 |
A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes H Nagai, JC Kagan, X Zhu, RA Kahn, CR Roy Science 295 (5555), 679-682, 2002 | 657 | 2002 |
Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites JC Kagan, CR Roy Nature cell biology 4 (12), 945-954, 2002 | 518 | 2002 |
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells I Zanoni, Y Tan, M Di Gioia, A Broggi, J Ruan, J Shi, CA Donado, F Shao, ... Science 352 (6290), 1232-1236, 2016 | 429 | 2016 |
Diverse intracellular pathogens activate type III interferon expression from peroxisomes C Odendall, E Dixit, F Stavru, H Bierne, KM Franz, AF Durbin, S Boulant, ... Nature immunology 15 (8), 717-726, 2014 | 371 | 2014 |
Legionella Subvert the Functions of Rab1 and Sec22b to Create a Replicative Organelle JC Kagan, MP Stein, M Pypaert, CR Roy The Journal of experimental medicine 199 (9), 1201-1211, 2004 | 333 | 2004 |
A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells H Nagai, ED Cambronne, JC Kagan, JC Amor, RA Kahn, CR Roy Proceedings of the National Academy of Sciences 102 (3), 826-831, 2005 | 330 | 2005 |
Early innate immune responses to bacterial LPS CV Rosadini, JC Kagan Current opinion in immunology 44, 14-19, 2017 | 309 | 2017 |
A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction KS Bonham, MH Orzalli, K Hayashi, AI Wolf, C Glanemann, W Weninger, ... Cell 156 (4), 705-716, 2014 | 269 | 2014 |
SMOCs: supramolecular organizing centres that control innate immunity JC Kagan, VG Magupalli, H Wu Nature Reviews Immunology 14 (12), 821-826, 2014 | 214 | 2014 |
Intracellular pathogen detection by RIG-I-like receptors E Dixit, JC Kagan Advances in immunology 117, 99-125, 2013 | 206 | 2013 |
Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth J Coers, JC Kagan, M Matthews, H Nagai, DM Zuckman, CR Roy Molecular microbiology 38 (4), 719-736, 2000 | 199 | 2000 |