The E2F transcription factor is a cellular target for the RB protein SP Chellappan, S Hiebert, M Mudryj, JM Horowitz, JR Nevins Cell 65 (6), 1053-1061, 1991 | 1920 | 1991 |
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product P Whyte, KJ Buchkovich, JM Horowitz, SH Friend, M Raybuck, ... Nature 334 (6178), 124-129, 1988 | 1888 | 1988 |
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. SW Hiebert, SP Chellappan, JM Horowitz, JR Nevins Genes & development 6 (2), 177-185, 1992 | 767 | 1992 |
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. JM Horowitz, SH Park, E Bogenmann, JC Cheng, DW Yandell, FJ Kaye, ... Proceedings of the National Academy of Sciences 87 (7), 2775-2779, 1990 | 765 | 1990 |
Point mutational inactivation of the retinoblastoma antioncogene JM Horowitz, DW Yandell, SH Park, S Canning, P Whyte, K Buchkovich, ... Science 243 (4893), 937-940, 1989 | 570 | 1989 |
Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein. SH Friend, JM Horowitz, MR Gerber, XF Wang, E Bogenmann, FP Li, ... Proceedings of the National Academy of Sciences 84 (24), 9059-9063, 1987 | 550 | 1987 |
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway RJ Lee, C Albanese, M Fu, M D'Amico, B Lin, G Watanabe, GK Haines III, ... Molecular and cellular biology 20 (2), 672-683, 2000 | 430 | 2000 |
Negative regulation of human c-fos expression by thes retinoblastoma gene product PD Robbins, JM Horowitz, RC Mulligan Nature 346 (6285), 668-671, 1990 | 368 | 1990 |
Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription SB Kennett, AJ Udvadia, JM Horowitz Nucleic acids research 25 (15), 3110-3117, 1997 | 325 | 1997 |
Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein. R Bernards, GM Schackleford, MR Gerber, JM Horowitz, SH Friend, ... Proceedings of the National Academy of Sciences 86 (17), 6474-6478, 1989 | 318 | 1989 |
Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest. GS Dbaibo, MY Pushkareva, S Jayadev, JK Schwarz, JM Horowitz, ... Proceedings of the National Academy of Sciences 92 (5), 1347-1351, 1995 | 294 | 1995 |
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding. FJ Kaye, RA Kratzke, JL Gerster, JM Horowitz Proceedings of the National Academy of Sciences 87 (17), 6922-6926, 1990 | 276 | 1990 |
Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7 JM Sterner, S Dew-Knight, C Musahl, S Kornbluth, JM Horowitz Molecular and cellular biology, 1998 | 270 | 1998 |
Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. AJ Udvadia, DJ Templeton, JM Horowitz Proceedings of the National Academy of Sciences 92 (9), 3953-3957, 1995 | 270 | 1995 |
Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression. AJ Udvadia, KT Rogers, PD Higgins, Y Murata, KH Martin, PA Humphrey, ... Proceedings of the National Academy of Sciences 90 (8), 3265-3269, 1993 | 247 | 1993 |
Molecular cloning and characterization of human nonsteroidal anti-inflammatory drug-activated gene promoter SJ Baek, JM Horowitz, TE Eling Journal of Biological Chemistry 276 (36), 33384-33392, 2001 | 188 | 2001 |
Subunit composition determines E2F DNA-binding site specificity Y Tao, RF Kassatly, WD Cress, JM Horowitz Molecular and cellular biology, 1997 | 172 | 1997 |
Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain. Y Murata, HG Kim, KT Rogers, AJ Udvadia, JM Horowitz Journal of Biological Chemistry 269 (32), 20674-20681, 1994 | 161 | 1994 |
Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1–independent mechanisms Y Rong, F Hu, RP Huang, N Mackman, JM Horowitz, RL Jensen, ... Cancer research 66 (14), 7067-7074, 2006 | 114 | 2006 |
Endogenous mouse leukemia viruses R Risser, JM Horowitz, J McCubrey Annual review of genetics 17 (1), 85-121, 1983 | 94 | 1983 |