Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies H Kim, M Rafiuddin-Shah, HC Tu, JR Jeffers, GP Zambetti, JJD Hsieh, ... Nature cell biology 8 (12), 1348-1358, 2006 | 1090 | 2006 |
BAX activation is initiated at a novel interaction site E Gavathiotis, M Suzuki, ML Davis, K Pitter, GH Bird, SG Katz, HC Tu, ... Nature 455 (7216), 1076-1081, 2008 | 848 | 2008 |
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis H Kim, HC Tu, D Ren, O Takeuchi, JR Jeffers, GP Zambetti, JJD Hsieh, ... Molecular cell 36 (3), 487-499, 2009 | 705 | 2009 |
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway H Kim, AD D'Andrea Genes & development 26 (13), 1393-1408, 2012 | 591 | 2012 |
BID, BIM, and PUMA are essential for activation of the BAX-and BAK-dependent cell death program D Ren, HC Tu, H Kim, GX Wang, GR Bean, O Takeuchi, JR Jeffers, ... Science 330 (6009), 1390-1393, 2010 | 547 | 2010 |
An interconnected hierarchical model of cell death regulation by the BCL-2 family HC Chen, M Kanai, A Inoue-Yamauchi, HC Tu, Y Huang, D Ren, H Kim, ... Nature cell biology 17 (10), 1270-1281, 2015 | 297 | 2015 |
Regulation of Rev1 by the Fanconi anemia core complex H Kim, K Yang, D Dejsuphong, AD D'Andrea Nature structural & molecular biology 19 (2), 164-170, 2012 | 170 | 2012 |
Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ J Wojtaszek, CJ Lee, S D'Souza, B Minesinger, H Kim, AD D'Andrea, ... Journal of Biological Chemistry 287 (40), 33836-33846, 2012 | 131 | 2012 |
The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage HC Tu, D Ren, GX Wang, DY Chen, TD Westergard, H Kim, S Sasagawa, ... Proceedings of the National Academy of Sciences 106 (4), 1093-1098, 2009 | 122 | 2009 |
FANCD2 activates transcription of TAp63 and suppresses tumorigenesis E Park, H Kim, JM Kim, B Primack, S Vidal-Cardenas, Y Xu, BD Price, ... Molecular cell 50 (6), 908-918, 2013 | 113 | 2013 |
Allosteric activation of ubiquitin-specific proteases by β-propeller proteins UAF1 and WDR20 H Li, KS Lim, H Kim, TR Hinds, U Jo, H Mao, CE Weller, J Sun, ... Molecular cell 63 (2), 249-260, 2016 | 61 | 2016 |
Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis H Kim, D Dejsuphong, G Adelmant, R Ceccaldi, K Yang, JA Marto, ... Molecular cell 54 (1), 107-118, 2014 | 59 | 2014 |
The VDAC2-BAK rheostat controls thymocyte survival D Ren, H Kim, HC Tu, TD Westergard, JK Fisher, JA Rubens, ... Science signaling 2 (85), ra48-ra48, 2009 | 57 | 2009 |
RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway J Xie, H Kim, LA Moreau, S Puhalla, J Garber, M Al Abo, S Takeda, ... The Journal of clinical investigation 125 (4), 1523-1532, 2015 | 43 | 2015 |
SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks J Rageul, JJ Park, PP Zeng, EA Lee, J Yang, S Hwang, N Lo, ... Nature Communications 11 (1), 5495, 2020 | 42 | 2020 |
PCNA-dependent cleavage and degradation of SDE2 regulates response to replication stress U Jo, W Cai, J Wang, Y Kwon, AD D’Andrea, H Kim PLoS genetics 12 (12), e1006465, 2016 | 40 | 2016 |
Fanconi anemia and the underlying causes of genomic instability J Rageul, H Kim Environmental and molecular mutagenesis 61 (7), 693-708, 2020 | 37 | 2020 |
Exploiting the Fanconi anemia pathway for targeted anti-cancer therapy U Jo, H Kim Molecules and cells 38 (8), 669-676, 2015 | 30 | 2015 |
Conditional degradation of SDE2 by the Arg/N-End rule pathway regulates stress response at replication forks J Rageul, JJ Park, U Jo, AS Weinheimer, TTM Vu, H Kim Nucleic acids research 47 (8), 3996-4010, 2019 | 22 | 2019 |
FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation J Wang, U Jo, SY Joo, H Kim Oncotarget 7 (24), 35724, 2016 | 18 | 2016 |