The Hsp70 chaperone network R Rosenzweig, NB Nillegoda, MP Mayer, B Bukau Nature reviews molecular cell biology 20 (11), 665-680, 2019 | 941 | 2019 |
Unraveling the mechanism of protein disaggregation through a ClpB-DnaK interaction R Rosenzweig, S Moradi, A Zarrine-Afsar, JR Glover, LE Kay Science 339 (6123), 1080-1083, 2013 | 286 | 2013 |
Bringing dynamic molecular machines into focus by methyl-TROSY NMR R Rosenzweig, LE Kay Annual review of biochemistry 83, 291-315, 2014 | 220 | 2014 |
HSP40 proteins use class-specific regulation to drive HSP70 functional diversity O Faust, M Abayev-Avraham, AS Wentink, M Maurer, NB Nillegoda, ... Nature 587 (7834), 489-494, 2020 | 161 | 2020 |
The central unit within the 19S regulatory particle of the proteasome R Rosenzweig, PA Osmulski, M Gaczynska, MH Glickman Nature structural & molecular biology 15 (6), 573-580, 2008 | 152 | 2008 |
Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome R Rosenzweig, V Bronner, D Zhang, D Fushman, MH Glickman Journal of Biological Chemistry 287 (18), 14659-14671, 2012 | 147 | 2012 |
Function, evolution, and structure of J-domain proteins HH Kampinga, C Andreasson, A Barducci, ME Cheetham, D Cyr, ... Cell Stress and Chaperones 24, 7-15, 2019 | 146 | 2019 |
Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry P Deriziotis, R André, DM Smith, R Goold, KJ Kinghorn, M Kristiansen, ... The EMBO journal 30 (15), 3065-3077, 2011 | 135 | 2011 |
Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor D Zhang, T Chen, I Ziv, R Rosenzweig, Y Matiuhin, V Bronner, ... Molecular cell 36 (6), 1018-1033, 2009 | 131 | 2009 |
Mapping the conformation of a client protein through the Hsp70 functional cycle A Sekhar, R Rosenzweig, G Bouvignies, LE Kay Proceedings of the National Academy of Sciences 112 (33), 10395-10400, 2015 | 103 | 2015 |
Hsp70 biases the folding pathways of client proteins A Sekhar, R Rosenzweig, G Bouvignies, LE Kay Proceedings of the National Academy of Sciences 113 (20), E2794-E2801, 2016 | 98 | 2016 |
Site-directed methyl group labeling as an NMR probe of structure and dynamics in supramolecular protein systems: applications to the proteasome and to the ClpP protease TL Religa, AM Ruschak, R Rosenzweig, LE Kay Journal of the American Chemical Society 133 (23), 9063-9068, 2011 | 96 | 2011 |
ClpB N-terminal domain plays a regulatory role in protein disaggregation R Rosenzweig, P Farber, A Velyvis, E Rennella, MP Latham, LE Kay Proceedings of the National Academy of Sciences 112 (50), E6872-E6881, 2015 | 95 | 2015 |
Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles R Rosenzweig, A Sekhar, J Nagesh, LE Kay Elife 6, e28030, 2017 | 81 | 2017 |
Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions A Sekhar, A Velyvis, G Zoltsman, R Rosenzweig, G Bouvignies, LE Kay Elife 7, e32764, 2018 | 80 | 2018 |
Tunable microsecond dynamics of an allosteric switch regulate the activity of a AAA+ disaggregation machine H Mazal, M Iljina, Y Barak, N Elad, R Rosenzweig, P Goloubinoff, I Riven, ... Nature communications 10 (1), 1438, 2019 | 51 | 2019 |
Chaperone-driven proteasome assembly R Rosenzweig, MH Glickman Biochemical Society Transactions 36 (5), 807-812, 2008 | 47 | 2008 |
Polyubiquitin-photoactivatable crosslinking reagents for mapping ubiquitin interactome identify Rpn1 as a proteasome ubiquitin-associating subunit M Chojnacki, W Mansour, DS Hameed, RK Singh, F El Oualid, ... Cell chemical biology 24 (4), 443-457. e6, 2017 | 42 | 2017 |
Electron microscopic evidence in support of α-solenoid models of proteasomal subunits Rpn1 and Rpn2 G Effantin, R Rosenzweig, MH Glickman, AC Steven Journal of molecular biology 386 (5), 1204-1211, 2009 | 42 | 2009 |
Hsp40s play complementary roles in the prevention of tau amyloid formation R Irwin, O Faust, I Petrovic, SG Wolf, H Hofmann, R Rosenzweig Elife 10, e69601, 2021 | 39 | 2021 |