Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases JY van der Meer, H Poddar, BJ Baas, Y Miao, M Rahimi, A Kunzendorf, ... Nature communications 7 (1), 10911, 2016 | 91 | 2016 |
Evidence for the formation of an enamine species during aldol and Michael‐type addition reactions promiscuously catalyzed by 4‐oxalocrotonate tautomerase H Poddar, M Rahimi, EM Geertsema, AMWH Thunnissen, GJ Poelarends ChemBioChem 16 (5), 738-741, 2015 | 37 | 2015 |
A guide to time‐resolved structural analysis of light‐activated proteins H Poddar, DJ Heyes, G Schirò, M Weik, D Leys, NS Scrutton The FEBS Journal 289 (3), 576-595, 2022 | 34 | 2022 |
Structural Basis for the Catalytic Mechanism of Ethylenediamine-N,N′-disuccinic Acid Lyase, a Carbon–Nitrogen Bond-Forming Enzyme with a Broad Substrate … H Poddar, J De Villiers, J Zhang, V Puthan Veetil, H Raj, ... Biochemistry 57 (26), 3752-3763, 2018 | 28 | 2018 |
Structure–Activity Relationships of cyclo(l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to … S Rajput, KJ McLean, H Poddar, IR Selvam, G Nagalingam, JA Triccas, ... Journal of Medicinal Chemistry 62 (21), 9792-9805, 2019 | 22 | 2019 |
Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs LN Jeffreys, H Poddar, M Golovanova, CW Levy, HM Girvan, KJ McLean, ... Scientific Reports 9 (1), 1577, 2019 | 22 | 2019 |
Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus HM Girvan, H Poddar, KJ McLean, DR Nelson, KA Hollywood, CW Levy, ... Journal of Inorganic Biochemistry 188, 18-28, 2018 | 20 | 2018 |
Towards engineering and production of artificial spider silk using tools of synthetic biology H Poddar, R Breitling, E Takano Engineering Biology 4 (1), 1-6, 2020 | 19 | 2020 |
Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4‐Oxalocrotonate Tautomerase More Effectively than Distant Mutations M Rahimi, JY van der Meer, EM Geertsema, H Poddar, BJ Baas, ... ChemBioChem 17 (13), 1225-1228, 2016 | 18 | 2016 |
Functional and structural characterization of an unusual cofactor-independent oxygenase BJ Baas, H Poddar, EM Geertsema, HJ Rozeboom, MP de Vries, ... Biochemistry 54 (5), 1219-1232, 2015 | 17 | 2015 |
WH; Poelarends, GJ Evidence for the Formation of an Enamine Species During Aldol and Michael-Type Addition Reactions Promiscuously Catalyzed by 4-Oxalocrotonate Tautomerase H Poddar, M Rahimi, EM Geertsema, AM Thunnissen Chem-BioChem 16, 738-741, 2015 | 7 | 2015 |
An unusual light-sensing function for coenzyme B12 in bacterial transcription regulator CarH H Poddar, DJ Heyes, S Zhang, SJ Hardman, M Sakuma, NS Scrutton Methods in Enzymology 668, 349-372, 2022 | 2 | 2022 |
Redox driven B12-ligand switch drives CarH photoresponse H Poddar, R Rios-Santacruz, DJ Heyes, M Shanmugam, A Brookfield, ... Nature Communications 14 (1), 5082, 2023 | 1 | 2023 |
Corrigendum: Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4‐Oxalocrotonate Tautomerase More Effectively than Distant Mutations M Rahimi, JY van der Meer, EM Geertsema, H Poddar, BJ Baas, ... ChemBioChem 17 (13), 1290-1290, 2016 | 1 | 2016 |
Photocobilins integrate B12 and bilin photochemistry for enzyme control S Zhang, LN Jeffreys, H Poddar, Y Yu, C Liu, K Patel, LO Johannissen, ... Nature Communications 15 (1), 2740, 2024 | | 2024 |
Photocobilins integrate B12 and bilin photochemistry for enzyme control N Scrutton, S Zhang, H Poddar, Y Yu, C Liu, K Patel, L Jeffreys, L Zhu, ... | | 2023 |
Means and methods for synthesizing precursors of y-aminobutyric acid (gaba) analogs GJ POELARENDS, L BIEWENGA, JY VAN DER MEER, H PODDAR, ... EP Patent EP3,599,246, 2020 | | 2020 |
Structural and functional characterization of tautomerase and aspartase/fumarase superfamily enzymes H Poddar | | 2020 |