Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction AB Lopez‐Rodriguez, E Hennessy, CL Murray, A Nazmi, HJ Delaney, ... Alzheimer's & Dementia 17 (10), 1735-1755, 2021 | 133 | 2021 |
The influence of cannabinoids on generic traits of neurodegeneration SG Fagan, VA Campbell British Journal of pharmacology 171 (6), 1347-1360, 2014 | 102 | 2014 |
tRNA-derived fragments: A new class of non-coding RNA with key roles in nervous system function and dysfunction SG Fagan, M Helm, JHM Prehn Progress in neurobiology 205, 102118, 2021 | 36 | 2021 |
Fingolimod rescues demyelination in a mouse model of Krabbe's disease S Béchet, SA O'Sullivan, J Yssel, SG Fagan, KK Dev Journal of Neuroscience 40 (15), 3104-3118, 2020 | 28 | 2020 |
Fingolimod rescues memory and improves pathological hallmarks in the 3xTg-AD model of Alzheimer’s disease SG Fagan, S Bechet, KK Dev Molecular neurobiology, 1-14, 2022 | 23 | 2022 |
Microglial and Astrocyte priming in the APP/PS1 model of Alzheimer’s Disease: increased vulnerability to acute inflammation and cognitive deficits AB Lopez-Rodriguez, E Hennessy, C Murray, A Lewis, N Barra, S Fagan, ... bioRxiv, 344218, 2018 | 14 | 2018 |
Mapping the binding site topology of amyloid protein aggregates using multivalent ligands E Sanna, M Rodrigues, SG Fagan, TS Chisholm, K Kulenkampff, ... Chemical Science 12 (25), 8892-8899, 2021 | 11 | 2021 |
Synthesis and assessment of novel probes for imaging tau pathology in transgenic mouse and rat models L McMurray, JA Macdonald, NK Ramakrishnan, Y Zhao, DW Williamson, ... ACS Chemical Neuroscience 12 (11), 1885-1893, 2021 | 9 | 2021 |
Endocannabinoids and Alzheimer’s disease SG Fagan, VA Campbell Cannabinoids in Neurologic and Mental Disease, 15-33, 2015 | 7 | 2015 |
Preparation and characterization and radiolabelling of multivalent ligands towards positron emission tomography imaging of oligomeric forms of misfolded proteins involved in … S Thompson, E Sanna, S Fagan, MG Spillantini, C Hunter, F Aigbirhio Nuclear Medicine and Biology 108, S107-S108, 2022 | 1 | 2022 |
Emerging Roles of Non-Coding RNA in Neuronal Function and Dysfunction SG Fagan, S Pfeiffer COVID-19, Neuroimmunology and Neural Function, 2021 | | 2021 |
Targeting the sphingosine 1-phosphate axis leads to phenotypic improvements and reduced neuropathology in a murine model of Krabbe's disease. S Bechet, SG Fagan, S O'Sullivan, KK Dev GLIA 67, E221-E221, 2019 | | 2019 |
Investigating the effects of FTY720 on the neuroinflammatory profile of Alzheimer's disease LR Davison, SG Fagan, KK Dev GLIA 67, E238-E238, 2019 | | 2019 |
Sphingosine 1-phosphate receptor modulation reduces demyelination in a murine model of Krabbe disease S Bechet, S Fagan, SO Sullivan, J Yssel, K Dev GLIA 65, E374-E375, 2017 | | 2017 |
The effects of S1P receptor modulation in an animal model of Krabbes disease S Fagan, S Bechet, J Yssel, S O'Sullivan, K Dev GLIA 65, E186-E186, 2017 | | 2017 |
The involvement of PANX-1 in amyloid-induced neurodegeneration and the protective effect of the endocannabinoid system SG Fagan, C Rispin-Dureuil, T Lyons, VA Campbell IRISH JOURNAL OF MEDICAL SCIENCE 185, S179-S179, 2016 | | 2016 |
An Investigation of PANX 1 Membrane Channels in Cannabinoid Mediated Neuroprotection SG Fagan, VA Campbell IRISH JOURNAL OF MEDICAL SCIENCE 185, S22-S22, 2016 | | 2016 |
Pannexi 1 and Cannabinoid-mediated Neuroprotection S Fagan Trinity College Dublin, 2016 | | 2016 |
Modulation of the endocannabinoid system and PanX1-mediated neuroinflammation in an in vitro model of Alzheimer's disease SG Fagan, VA Campbell Journal of Neuroimmunology 275 (1), 125, 2014 | | 2014 |
The effect of cannabinoid treatment on amyloid-induced inflammation via the hemichannel, PANX1 SG Fagan, VA Campbell IRISH JOURNAL OF MEDICAL SCIENCE 183, S83-S84, 2014 | | 2014 |