ATF6 decreases myocardial ischemia/reperfusion damage and links ER stress and oxidative stress signaling pathways in the heart JK Jin, EA Blackwood, K Azizi, DJ Thuerauf, AG Fahem, C Hofmann, ... Circulation research 120 (5), 862-875, 2017 | 276 | 2017 |
Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion CC Glembotski, DJ Thuerauf, C Huang, JA Vekich, RA Gottlieb, ... Journal of Biological Chemistry 287 (31), 25893-25904, 2012 | 218 | 2012 |
Ischemia activates the ATF6 branch of the endoplasmic reticulum stress response S Doroudgar, DJ Thuerauf, MC Marcinko, PJ Belmont, CC Glembotski Journal of Biological Chemistry 284 (43), 29735-29745, 2009 | 193 | 2009 |
The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart S Doroudgar, CC Glembotski Trends in molecular medicine 17 (4), 207-214, 2011 | 127 | 2011 |
Hrd1 and ER-associated protein degradation, ERAD, are critical elements of the adaptive ER stress response in cardiac myocytes S Doroudgar, M Völkers, DJ Thuerauf, M Khan, S Mohsin, JL Respress, ... Circulation research 117 (6), 536-546, 2015 | 117 | 2015 |
Muscle 2-Volume Set: Fundamental Biology and Mechanisms of Disease J Hill, E Olson Academic Press, 2012 | 111 | 2012 |
Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage M Völkers, MH Konstandin, S Doroudgar, H Toko, P Quijada, S Din, ... Circulation 128 (19), 2132-2144, 2013 | 108 | 2013 |
Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1 M Völkers, H Toko, S Doroudgar, S Din, P Quijada, AY Joyo, L Ornelas, ... Proceedings of the National Academy of Sciences 110 (31), 12661-12666, 2013 | 105 | 2013 |
New concepts of endoplasmic reticulum function in the heart: programmed to conserve S Doroudgar, CC Glembotski Journal of Molecular and Cellular Cardiology 55, 85-91, 2013 | 100 | 2013 |
ATF6 regulates cardiac hypertrophy by transcriptional induction of the mTORC1 activator, Rheb EA Blackwood, C Hofmann, M Santo Domingo, AS Bilal, A Sarakki, ... Circulation research 124 (1), 79-93, 2019 | 93 | 2019 |
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release JO Reynolds, AP Quick, Q Wang, DL Beavers, LE Philippen, J Showell, ... International journal of cardiology 225, 371-380, 2016 | 88 | 2016 |
PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity M Völkers, S Doroudgar, N Nguyen, MH Konstandin, P Quijada, S Din, ... EMBO molecular medicine 6 (1), 57-65, 2014 | 77 | 2014 |
Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1 H Toko, MH Konstandin, S Doroudgar, L Ormachea, E Joyo, AY Joyo, ... Circulation research 112 (9), 1244-1252, 2013 | 56 | 2013 |
Monitoring cell-type–specific gene expression using ribosome profiling in vivo during cardiac hemodynamic stress S Doroudgar, C Hofmann, E Boileau, B Malone, E Riechert, AA Gorska, ... Circulation research 125 (4), 431-448, 2019 | 54 | 2019 |
CRISPR-mediated activation of endogenous gene expression in the postnatal heart E Schoger, KJ Carroll, LM Iyer, JR McAnally, W Tan, N Liu, C Noack, ... Circulation research 126 (1), 6-24, 2020 | 45 | 2020 |
Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response D Eletto, A Maganty, D Eletto, D Dersh, C Makarewich, C Biswas, ... Journal of cell science 125 (20), 4865-4875, 2012 | 45 | 2012 |
Protein misfolding in cardiac disease C Hofmann, HA Katus, S Doroudgar Circulation 139 (18), 2085-2088, 2019 | 42 | 2019 |
ER stress-induced secretion of proteins and their extracellular functions in the heart BA Meyer, S Doroudgar Cells 9 (9), 2066, 2020 | 37 | 2020 |
Mesencephalic astrocyte–derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart A Arrieta, EA Blackwood, WT Stauffer, M Santo Domingo, AS Bilal, ... Journal of Biological Chemistry 295 (22), 7566-7583, 2020 | 35 | 2020 |
Cardiovascular adverse events in multiple myeloma patients MB Heckmann, S Doroudgar, HA Katus, LH Lehmann Journal of thoracic disease 10 (Suppl 35), S4296, 2018 | 30 | 2018 |