Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells N Hattori, K Nishino, Y Ko, N Hattori, J Ohgane, S Tanaka, K Shiota Journal of Biological Chemistry 279 (17), 17063-17069, 2004 | 515 | 2004 |
Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells N Hattori, Y Imao, K Nishino, N Hattori, J Ohgane, S Yagi, S Tanaka, ... Genes to Cells 12 (3), 387-396, 2007 | 227 | 2007 |
DNA methylation-mediated control of Sry gene expression in mouse gonadal development K Nishino, N Hattori, S Tanaka, K Shiota Journal of Biological Chemistry 279 (21), 22306-22313, 2004 | 177 | 2004 |
DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression S Yagi, K Hirabayashi, S Sato, W Li, Y Takahashi, T Hirakawa, G Wu, ... Genome research 18 (12), 1969-1978, 2008 | 176 | 2008 |
Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway FZ Wei, Z Cao, X Wang, H Wang, MY Cai, T Li, N Hattori, D Wang, Y Du, ... Autophagy 11 (12), 2309-2322, 2015 | 155 | 2015 |
Apolipoprotein AI deficiency due to a codon 84 nonsense mutation of the apolipoprotein AI gene. T Matsunaga, Y Hiasa, H Yanagi, T Maeda, N Hattori, K Yamakawa, ... Proceedings of the National Academy of Sciences 88 (7), 2793-2797, 1991 | 149 | 1991 |
Molecular Pathways: Involvement of Helicobacter pylori–Triggered Inflammation in the Formation of an Epigenetic Field Defect, and Its Usefulness as Cancer Risk … T Ushijima, N Hattori Clinical Cancer Research 18 (4), 923-929, 2012 | 138 | 2012 |
Epigenetic impact of infection on carcinogenesis: mechanisms and applications N Hattori, T Ushijima Genome medicine 8, 1-13, 2016 | 122 | 2016 |
Stage-by-stage change in DNA methylation status of Dnmt1 locus during mouse early development YG Ko, K Nishino, N Hattori, Y Arai, S Tanaka, K Shiota Journal of Biological Chemistry 280 (10), 9627-9634, 2005 | 122 | 2005 |
Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells N Hattori, T Abe, N Hattori, M Suzuki, T Matsuyama, S Yoshida, E Li, ... Genome research 14 (9), 1733-1740, 2004 | 106 | 2004 |
Large-scale characterization of DNA methylation changes in human gastric carcinomas with and without metastasis Z Liu, J Zhang, Y Gao, L Pei, J Zhou, L Gu, L Zhang, B Zhu, N Hattori, J Ji, ... Clinical cancer research 20 (17), 4598-4612, 2014 | 89 | 2014 |
Genetic and epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues S Yamashita, T Kishino, T Takahashi, T Shimazu, H Charvat, Y Kakugawa, ... Proceedings of the national academy of sciences 115 (6), 1328-1333, 2018 | 88 | 2018 |
Identification of coexistence of DNA methylation and H3K27me3 specifically in cancer cells as a promising target for epigenetic therapy H Takeshima, M Wakabayashi, N Hattori, S Yamashita, T Ushijima Carcinogenesis 36 (2), 192-201, 2015 | 82 | 2015 |
ANGPTL4 is a secreted tumor suppressor that inhibits angiogenesis E Okochi-Takada, N Hattori, T Tsukamoto, K Miyamoto, T Ando, S Ito, ... Oncogene 33 (17), 2273-2278, 2014 | 80 | 2014 |
Compendium of aberrant DNA methylation and histone modifications in cancer N Hattori, T Ushijima Biochemical and biophysical research communications 455 (1-2), 3-9, 2014 | 70 | 2014 |
Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3 M Maeda, H Takeshima, N Iida, N Hattori, S Yamashita, H Moro, ... Gut 69 (2), 243-251, 2020 | 62 | 2020 |
Antibiotics suppress colon tumorigenesis through inhibition of aberrant DNA methylation in an azoxymethane and dextran sulfate sodium colitis model N Hattori, T Niwa, T Ishida, K Kobayashi, T Imai, A Mori, K Kimura, T Mori, ... Cancer science 110 (1), 147-156, 2019 | 47 | 2019 |
An ultrasonographic method for detection of Achilles tendon xanthomas in familial hypercholesterolemia K Yuzawa, K Yamakawa, E Tohno, M Seki, M Akisada, H Yanagi, ... Atherosclerosis 75 (2-3), 211-218, 1989 | 42 | 1989 |
Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells N Hattori, T Niwa, K Kimura, K Helin, T Ushijima Nucleic acids research 41 (15), 7231-7239, 2013 | 40 | 2013 |
Targeting of super-enhancers and mutant BRAF can suppress growth of BRAF-mutant colon cancer cells via repression of MAPK signaling pathway Y Nakamura, N Hattori, N Iida, S Yamashita, A Mori, K Kimura, T Yoshino, ... Cancer letters 402, 100-109, 2017 | 36 | 2017 |