Pathophysiology, treatment, and animal and cellular models of human ischemic stroke TM Woodruff, J Thundyil, SC Tang, CG Sobey, SM Taylor, TV Arumugam Molecular neurodegeneration 6, 1-19, 2011 | 769 | 2011 |
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke YW D Fann, SY Lee, S Manzanero, SC Tang, M Gelderblom, P Chunduri, ... Cell death & disease 4 (9), e790-e790, 2013 | 449 | 2013 |
Toll-like receptors in ischemia-reperfusion injury TV Arumugam, E Okun, SC Tang, J Thundyil, SM Taylor, TM Woodruff Shock 32 (1), 4-16, 2009 | 412 | 2009 |
Adiponectin receptor signalling in the brain J Thundyil, D Pavlovski, CG Sobey, TV Arumugam British journal of pharmacology 165 (2), 313-327, 2012 | 299 | 2012 |
Mitochondrial dysfunction and Parkinson disease: a Parkin–AMPK alliance in neuroprotection L Hang, J Thundyil, KL Lim Annals of the New York Academy of Sciences 1350 (1), 37-47, 2015 | 115 | 2015 |
Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis D Pavlovski, J Thundyil, PN Monk, RA Wetsel, SM Taylor, TM Woodruff The FASEB Journal 26 (9), 3680-3690, 2012 | 114 | 2012 |
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice M Gelderblom, F Leypoldt, J Lewerenz, G Birkenmayer, D Orozco, ... Journal of Cerebral Blood Flow & Metabolism 32 (5), 835-843, 2012 | 111 | 2012 |
Evidence that γ-secretase-mediated notch signaling induces neuronal cell death via the nuclear factor-κB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke TV Arumugam, YL Cheng, Y Choi, YH Choi, S Yang, YK Yun, JS Park, ... Molecular Pharmacology 80 (1), 23-31, 2011 | 98 | 2011 |
DAMPs and neurodegeneration J Thundyil, KL Lim Ageing research reviews 24, 17-28, 2015 | 96 | 2015 |
Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death J Thundyil, SC Tang, E Okun, K Shah, VT Karamyan, YI Li, TM Woodruff, ... Experimental & translational stroke medicine 2, 1-8, 2010 | 65 | 2010 |
Evidence that the EphA2 receptor exacerbates ischemic brain injury J Thundyil, S Manzanero, D Pavlovski, TR Cully, KZ Lok, A Widiapradja, ... PLoS One 8 (1), e53528, 2013 | 62 | 2013 |
Intravenous immunoglobulin protects neurons against amyloid beta‐peptide toxicity and ischemic stroke by attenuating multiple cell death pathways A Widiapradja, V Vegh, KZ Lok, S Manzanero, J Thundyil, M Gelderblom, ... Journal of neurochemistry 122 (2), 321-332, 2012 | 53 | 2012 |
Intestinal ischemia-reperfusion injury leads to inflammatory changes in the brain YH Hsieh, K McCartney, TA Moore, J Thundyil, M Gelderblom, ... Shock 36 (4), 424-430, 2011 | 52 | 2011 |
Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke JD Lathia, S Chigurupati, J Thundyil, PK Selvaraj, MR Mughal, ... Experimental Neurology 221 (1), 107-114, 2010 | 34 | 2010 |
C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model J Thundyil, D Pavlovski, YH Hsieh, M Gelderblom, T Magnus, DP Fairlie, ... Neuromolecular medicine 14, 30-39, 2012 | 18 | 2012 |
AMP kinase activation is selectively disrupted in the ventral midbrain of mice deficient in Parkin or PINK1 expression L Hang, J Thundyil, GWY Goh, KL Lim NeuroMolecular Medicine 21, 25-32, 2019 | 16 | 2019 |
Over-expression of DSCR1 protects against post-ischemic neuronal injury VH Brait, KR Martin, A Corlett, BRS Broughton, HA Kim, J Thundyil, ... PLoS One 7 (10), e47841, 2012 | 14 | 2012 |
Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson's disease-associated phenotypes in vivo L Hang, Z Wang, ASC Foo, GWY Goh, HC Choong, J Thundyil, S Xu, ... Neurobiology of Disease 161, 105560, 2021 | 13 | 2021 |
Neutralizing and Total/IgG spike antibody responses following homologous CoronaVac vs. BNT162b2 vaccination up to 90 days post-booster CS Lau, J Thundyil, MLH Oh, SK Phua, YL Liang, Y Li, J Huo, Y Huang, ... Antibodies 11 (4), 70, 2022 | 7 | 2022 |
Parkin regulates neuronal lipid homeostasis through SREBP2-lipoprotein lipase pathway—implications for Parkinson’s disease W Tang, J Thundyil, GGY Lim, TJW Tng, SQZ Yeow, A Nair, C Chai, ... Human Molecular Genetics 32 (9), 1466-1482, 2023 | 6 | 2023 |