| New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment LC Cheung, J Tickner, AM Hughes, P Skut, M Howlett, B Foley, ... Leukemia 32 (11), 2326-2338, 2018 | 39 | 2018 |
| Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin MN Cruickshank, J Ford, LC Cheung, J Heng, S Singh, J Wells, TW Failes, ... Leukemia 31 (1), 40-50, 2017 | 34 | 2017 |
| Targeting cytokine-and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma R De Smedt, J Morscio, L Reunes, J Roels, V Bardelli, B Lintermans, ... Blood, The Journal of the American Society of Hematology 135 (19), 1685-1695, 2020 | 32 | 2020 |
| RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia F Matthijssens, ND Sharma, M Nysus, CK Nickl, H Kang, DR Perez, ... The Journal of clinical investigation 131 (6), 2021 | 29 | 2021 |
| Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia J Roels, M Thénoz, B Szarzyńska, M Landfors, S De Coninck, L Demoen, ... Blood cancer discovery 1 (3), 274-289, 2020 | 28 | 2020 |
| A novel, palatable paediatric oral formulation of midazolam: pharmacokinetics, tolerability, efficacy and safety S Salman, EKY Tang, LC Cheung, MN Nguyen, D Sommerfield, L Slevin, ... Anaesthesia 73 (12), 1469-1477, 2018 | 26 | 2018 |
| Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis LC Cheung, DH Strickland, M Howlett, J Ford, AK Charles, KM Lyons, ... haematologica 99 (7), 1149, 2014 | 24 | 2014 |
| Taste evaluation of a novel midazolam tablet for pediatric patients: In vitro drug dissolution, in vivo animal taste aversion and clinical taste perception profiles LC Cheung, M Nguyen, E Tang, BS von Ungern Sternberg, S Salman, ... International journal of pharmaceutics 535 (1-2), 194-200, 2018 | 22 | 2018 |
| Therapeutic targeting of the leukaemia microenvironment V Kuek, AM Hughes, RS Kotecha, LC Cheung International journal of molecular sciences 22 (13), 6888, 2021 | 21 | 2021 |
| Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in down syndrome b-cell leukemia AP Laurent, A Siret, C Ignacimouttou, K Panchal, MB Diop, S Jenni, ... Clinical Cancer Research 26 (13), 3307-3318, 2020 | 20 | 2020 |
| Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy LC Cheung, C Aya-Bonilla, MN Cruickshank, SK Chiu, V Kuek, ... Leukemia 37 (1), 61-71, 2023 | 19 | 2023 |
| Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin M Karsa, A Kosciolek, A Bongers, A Mariana, T Failes, AJ Gifford, ... British Journal of Cancer 125 (1), 55-64, 2021 | 19 | 2021 |
| The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution D Anderson, P Skut, AM Hughes, E Ferrari, J Tickner, J Xu, BH Mullin, ... Scientific Reports 10 (1), 19173, 2020 | 18 | 2020 |
| The bone marrow microenvironment in B-cell development and malignancy AM Hughes, V Kuek, RS Kotecha, LC Cheung Cancers 14 (9), 2089, 2022 | 16 | 2022 |
| Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia LC Cheung, R de Kraa, J Oommen, GA Chua, S Singh, AM Hughes, ... Frontiers in Oncology 11, 631594, 2021 | 14 | 2021 |
| Immunogenicity of the inactivated influenza vaccine in children who have undergone allogeneic haematopoietic stem cell transplant AL Ryan, UD Wadia, P Jacoby, LC Cheung, F Kerr, C Fraser, H Tapp, ... Bone marrow transplantation 55 (4), 773-779, 2020 | 13 | 2020 |
| Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute … LC Cheung, MN Cruickshank, AM Hughes, S Singh, GA Chua, J Ford, ... haematologica 104 (7), e300, 2019 | 12 | 2019 |
| The combination of curaxin CBL0137 and histone deacetylase inhibitor panobinostat delays KMT2A-rearranged leukemia progression L Xiao, M Karsa, E Ronca, A Bongers, A Kosciolek, A El-Ayoubi, ... Frontiers in Oncology 12, 863329, 2022 | 10 | 2022 |
| Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia E Moles, CB Howard, P Huda, M Karsa, H McCalmont, K Kimpton, A Duly, ... Science Translational Medicine 15 (696), eabm1262, 2023 | 9 | 2023 |
| Identifying the optimal donor for natural killer cell adoptive therapy to treat paediatric B‐and T‐cell acute lymphoblastic leukaemia B Foley, C Ta, S Barnes, E de Jong, M Nguyen, LC Cheung, A Buzzai, ... Clinical & Translational Immunology 9 (7), e1151, 2020 | 8 | 2020 |
