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Gary P. H. Ho
Gary P. H. Ho
Assistant Professor of Neurology, Harvard Medical School and Brigham and Women's Hospital
在 bwh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Lipidomic analysis of α-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment
S Fanning, A Haque, T Imberdis, V Baru, MI Barrasa, S Nuber, D Termine, ...
Molecular cell 73 (5), 1001-1014. e8, 2019
2392019
S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95
GPH Ho, B Selvakumar, J Mukai, LD Hester, Y Wang, JA Gogos, ...
Neuron 71 (1), 131-141, 2011
1652011
Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance
GPH Ho, S Margossian, T Taniguchi, AD D'Andrea
Molecular and cellular biology, 2006
1642006
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation
AK Mustafa, M Kumar, B Selvakumar, GPH Ho, JT Ehmsen, RK Barrow, ...
Proceedings of the National Academy of Sciences 104 (8), 2950-2955, 2007
1622007
DNA damage responses and their many interactions with the replication fork
PR Andreassen, GPH Ho, AD D'Andrea
Carcinogenesis 27 (5), 883-892, 2006
1412006
Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase
T Imberdis, J Negri, N Ramalingam, E Terry-Kantor, GPH Ho, S Fanning, ...
Proceedings of the National Academy of Sciences 116 (41), 20760-20769, 2019
812019
Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity
JY Cha, HJ Kim, JH Yu, J Xu, D Kim, BD Paul, H Choi, S Kim, YJ Lee, ...
Proceedings of the National Academy of Sciences 110 (51), 20575-20580, 2013
512013
Upregulation of Cellular Palmitoylation Mitigates α‐Synuclein Accumulation and Neurotoxicity
GPH Ho, N Ramalingam, T Imberdis, EC Wilkie, U Dettmer, DJ Selkoe
Movement Disorders 36 (2), 348-359, 2021
262021
Rapid alpha-synuclein toxicity in a neural cell model and its rescue by a stearoyl-CoA desaturase inhibitor
E Terry-Kantor, A Tripathi, T Imberdis, ZM LaVoie, GPH Ho, D Selkoe, ...
International journal of molecular sciences 21 (15), 5193, 2020
212020
Palmitoylation of the Parkinson’s disease–associated protein synaptotagmin-11 links its turnover to α-synuclein homeostasis
GPH Ho, EC Wilkie, AJ White, DJ Selkoe
Science signaling 16 (772), eadd7220, 2023
182023
Lipase regulation of cellular fatty acid homeostasis as a Parkinson’s disease therapeutic strategy
S Fanning, H Cirka, JL Thies, J Jeong, SM Niemi, J Yoon, GPH Ho, ...
NPJ Parkinson's disease 8 (1), 74, 2022
102022
Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping
A Ndayisaba, AT Pitaro, AS Willett, KA Jones, CM de Gusmao, AL Olsen, ...
The Cerebellum 23 (1), 31-51, 2024
32024
Increased palmitoylation improves estrogen receptor alpha–dependent hippocampal synaptic deficits in a mouse model of synucleinopathy
TE Moors, S Li, TD McCaffery, GPH Ho, PA Bechade, LN Pham, ...
Science Advances 9 (46), eadj1454, 2023
32023
Health phenome of Parkinson’s patients reveals prominent mood-sleep cluster
A Olsen, J Locascio, I Tuncali, N Laroussi, E Abatzis, P Kamenskaya, ...
Research Square, 2023
12023
Inhibiting the Depalmitoylase APT1 Protects Against Alpha-synuclein Neurotoxicity: A Novel Target for Disease-modifying Therapy in Human Synucleinopathies (697)
GPH Ho, N Ramalingam, EC Wilkie, T Imberdis, U Dettmer, D Selkoe
Neurology 94 (15_supplement), 697, 2020
12020
Impulsive behaviors: Definition, prevalence, neurobiology, and management
GPH Ho, CE Gamaldo, S Gulyani, RE Salas
Restless Legs Syndrome/Willis Ekbom Disease: Long-Term Consequences and …, 2017
12017
S-NITROSYLATION OF THE p53 TUMOR SUPPRESSOR PROTEIN INMEDULLOBLASTOMA
M Koldobskiy, I Ahmed, G Ho, A Snowman, E Raabe, C Eberhart, ...
NEURO-ONCOLOGY 15, 20-20, 2013
12013
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons
AJ White, KA Clark, KD Alexander, N Ramalingam, TL Young-Pearse, ...
npj Parkinson's Disease 10 (1), 107, 2024
2024
Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping
A Ndayisaba, AT Pitaro, AS Willett, KA Jones, CM de Gusmao, AL Olsen, ...
The Cerebellum 23 (1), 52-53, 2024
2024
Towards a phenome-wide view of Parkinson’s disease
AL Olsen, JJ Locascio, I Tuncali, N Laroussi, E Abatzis, P Kamenskaya, ...
medRxiv, 2022.02. 01.22270276, 2022
2022
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