Lipidomic analysis of α-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment S Fanning, A Haque, T Imberdis, V Baru, MI Barrasa, S Nuber, D Termine, ... Molecular cell 73 (5), 1001-1014. e8, 2019 | 239 | 2019 |
S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95 GPH Ho, B Selvakumar, J Mukai, LD Hester, Y Wang, JA Gogos, ... Neuron 71 (1), 131-141, 2011 | 165 | 2011 |
Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance GPH Ho, S Margossian, T Taniguchi, AD D'Andrea Molecular and cellular biology, 2006 | 164 | 2006 |
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation AK Mustafa, M Kumar, B Selvakumar, GPH Ho, JT Ehmsen, RK Barrow, ... Proceedings of the National Academy of Sciences 104 (8), 2950-2955, 2007 | 162 | 2007 |
DNA damage responses and their many interactions with the replication fork PR Andreassen, GPH Ho, AD D'Andrea Carcinogenesis 27 (5), 883-892, 2006 | 141 | 2006 |
Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase T Imberdis, J Negri, N Ramalingam, E Terry-Kantor, GPH Ho, S Fanning, ... Proceedings of the National Academy of Sciences 116 (41), 20760-20769, 2019 | 81 | 2019 |
Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity JY Cha, HJ Kim, JH Yu, J Xu, D Kim, BD Paul, H Choi, S Kim, YJ Lee, ... Proceedings of the National Academy of Sciences 110 (51), 20575-20580, 2013 | 51 | 2013 |
Upregulation of Cellular Palmitoylation Mitigates α‐Synuclein Accumulation and Neurotoxicity GPH Ho, N Ramalingam, T Imberdis, EC Wilkie, U Dettmer, DJ Selkoe Movement Disorders 36 (2), 348-359, 2021 | 26 | 2021 |
Rapid alpha-synuclein toxicity in a neural cell model and its rescue by a stearoyl-CoA desaturase inhibitor E Terry-Kantor, A Tripathi, T Imberdis, ZM LaVoie, GPH Ho, D Selkoe, ... International journal of molecular sciences 21 (15), 5193, 2020 | 21 | 2020 |
Palmitoylation of the Parkinson’s disease–associated protein synaptotagmin-11 links its turnover to α-synuclein homeostasis GPH Ho, EC Wilkie, AJ White, DJ Selkoe Science signaling 16 (772), eadd7220, 2023 | 18 | 2023 |
Lipase regulation of cellular fatty acid homeostasis as a Parkinson’s disease therapeutic strategy S Fanning, H Cirka, JL Thies, J Jeong, SM Niemi, J Yoon, GPH Ho, ... NPJ Parkinson's disease 8 (1), 74, 2022 | 10 | 2022 |
Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping A Ndayisaba, AT Pitaro, AS Willett, KA Jones, CM de Gusmao, AL Olsen, ... The Cerebellum 23 (1), 31-51, 2024 | 3 | 2024 |
Increased palmitoylation improves estrogen receptor alpha–dependent hippocampal synaptic deficits in a mouse model of synucleinopathy TE Moors, S Li, TD McCaffery, GPH Ho, PA Bechade, LN Pham, ... Science Advances 9 (46), eadj1454, 2023 | 3 | 2023 |
Health phenome of Parkinson’s patients reveals prominent mood-sleep cluster A Olsen, J Locascio, I Tuncali, N Laroussi, E Abatzis, P Kamenskaya, ... Research Square, 2023 | 1 | 2023 |
Inhibiting the Depalmitoylase APT1 Protects Against Alpha-synuclein Neurotoxicity: A Novel Target for Disease-modifying Therapy in Human Synucleinopathies (697) GPH Ho, N Ramalingam, EC Wilkie, T Imberdis, U Dettmer, D Selkoe Neurology 94 (15_supplement), 697, 2020 | 1 | 2020 |
Impulsive behaviors: Definition, prevalence, neurobiology, and management GPH Ho, CE Gamaldo, S Gulyani, RE Salas Restless Legs Syndrome/Willis Ekbom Disease: Long-Term Consequences and …, 2017 | 1 | 2017 |
S-NITROSYLATION OF THE p53 TUMOR SUPPRESSOR PROTEIN INMEDULLOBLASTOMA M Koldobskiy, I Ahmed, G Ho, A Snowman, E Raabe, C Eberhart, ... NEURO-ONCOLOGY 15, 20-20, 2013 | 1 | 2013 |
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons AJ White, KA Clark, KD Alexander, N Ramalingam, TL Young-Pearse, ... npj Parkinson's Disease 10 (1), 107, 2024 | | 2024 |
Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping A Ndayisaba, AT Pitaro, AS Willett, KA Jones, CM de Gusmao, AL Olsen, ... The Cerebellum 23 (1), 52-53, 2024 | | 2024 |
Towards a phenome-wide view of Parkinson’s disease AL Olsen, JJ Locascio, I Tuncali, N Laroussi, E Abatzis, P Kamenskaya, ... medRxiv, 2022.02. 01.22270276, 2022 | | 2022 |