关注
Laszlo Urban
Laszlo Urban
Head of Preclinical Secondary Pharmacology, NIBR
在 novartis.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Large-scale prediction and testing of drug activity on side-effect targets
E Lounkine, MJ Keiser, S Whitebread, D Mikhailov, J Hamon, JL Jenkins, ...
Nature 486 (7403), 361-367, 2012
9082012
Mechanisms of inflammatory pain
BL Kidd, LA Urban
British journal of anaesthesia 87 (1), 3-11, 2001
8852001
Epilepsy, hyperalgesia, impaired memory, and loss of pre-and postsynaptic GABAB responses in mice lacking GABAB (1)
V Schuler, C Lüscher, C Blanchet, N Klix, G Sansig, K Klebs, M Schmutz, ...
Neuron 31 (1), 47-58, 2001
6452001
A rat model of bone cancer pain
SJ Medhurst, K Walker, M Bowes, BL Kidd, M Glatt, M Muller, ...
Pain 96 (1), 129-140, 2002
5182002
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain
KM Walker, L Urban, SJ Medhurst, S Patel, M Panesar, AJ Fox, P McIntyre
Journal of pharmacology and experimental therapeutics 304 (1), 56-62, 2003
4472003
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain
A Fox, A Kesingland, C Gentry, K McNair, S Patel, L Urban, I James
Pain 92 (1), 91-100, 2001
4442001
Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development
S Whitebread, J Hamon, D Bojanic, L Urban
Drug discovery today 10 (21), 1421-1433, 2005
4192005
Analysis of pharmacology data and the prediction of adverse drug reactions and off‐target effects from chemical structure
A Bender, J Scheiber, M Glick, JW Davies, K Azzaoui, J Hamon, L Urban, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 861-873, 2007
3862007
Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat
AJ Reeve, S Patel, A Fox, K Walker, L Urban
European Journal of Pain 4 (3), 247-257, 2000
3752000
TRPV4: molecular conductor of a diverse orchestra
JPM White, M Cibelli, L Urban, B Nilius, JG McGeown, I Nagy
Physiological reviews 96 (3), 911-973, 2016
3742016
Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons
J Ahluwalia, L Urban, M Capogna, S Bevan, I Nagy
Neuroscience 100 (4), 685-688, 2000
3642000
Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters
L Urban, SWN Thompson, A Dray
Trends in neurosciences 17 (10), 432-438, 1994
3501994
The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology
I Nagy, P Sántha, G Jancsó, L Urbán
European journal of pharmacology 500 (1-3), 351-369, 2004
3492004
Pharmacology of chronic pain
A Dray, L Urban, A Dickenson
Trends in pharmacological sciences 15 (6), 190-197, 1994
3451994
Slow excitatory transmission in rat dorsal horn: possible mediation by peptides
L Urban, M Randić
Brain research 290 (2), 336-341, 1984
2731984
Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat
A Fox, C Eastwood, C Gentry, D Manning, L Urban
Pain 81 (3), 307-316, 1999
2721999
mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia
K Walker, A Reeve, M Bowes, J Winter, G Wotherspoon, A Davis, ...
Neuropharmacology 40 (1), 10-19, 2001
2632001
The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat
S Patel, S Naeem, A Kesingland, W Froestl, M Capogna, L Urban, A Fox
Pain 90 (3), 217-226, 2001
2442001
An in vitro study of the properties of single vagal afferents innervating guinea‐pig airways.
AJ Fox, PJ Barnes, L Urban, A Dray
The Journal of Physiology 469 (1), 21-35, 1993
2121993
Modeling promiscuity based on in vitro safety pharmacology profiling data
K Azzaoui, J Hamon, B Faller, S Whitebread, E Jacoby, A Bender, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 874-880, 2007
2052007
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