DNA-binding specificities of human transcription factors A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ... Cell 152 (1), 327-339, 2013 | 1378 | 2013 |
Impact of cytosine methylation on DNA binding specificities of human transcription factors Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ... Science 356 (6337), eaaj2239, 2017 | 1112 | 2017 |
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011 | 740 | 2011 |
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ... The EMBO journal 29 (13), 2147-2160, 2010 | 663 | 2010 |
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling S Tuupanen, M Turunen, R Lehtonen, O Hallikas, S Vanharanta, T Kivioja, ... Nature genetics 41 (8), 885-890, 2009 | 598 | 2009 |
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities A Jolma, T Kivioja, J Toivonen, L Cheng, G Wei, M Enge, M Taipale, ... Genome research 20 (6), 861-873, 2010 | 529 | 2010 |
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ... Cell 154 (4), 801-813, 2013 | 385 | 2013 |
Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ... Science 338 (6112), 1360-1363, 2012 | 237 | 2012 |
A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding Q Huang, T Whitington, P Gao, JF Lindberg, Y Yang, J Sun, MR Väisänen, ... Nature genetics 46 (2), 126-135, 2014 | 226 | 2014 |
Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers J Yan, SAA Chen, A Local, T Liu, Y Qiu, KM Dorighi, S Preissl, CM Rivera, ... Cell research 28 (2), 204, 2018 | 181 | 2018 |
Super-enhancers in transcriptional regulation and genome organization X Wang, MJ Cairns, J Yan Nucleic acids research 47 (22), 11481-11496, 2019 | 117 | 2019 |
Systematic analysis of binding of transcription factors to noncoding variants J Yan, Y Qiu, AMR Dos Santos, Y Yin, YE Li, N Vinckier, N Nariai, ... Nature 591, 147-151, 2021 | 107 | 2021 |
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk WW Greenwald, J Chiou, J Yan, Y Qiu, N Dai, A Wang, N Nariai, ... Nature communications 10 (1), 2078, 2019 | 97 | 2019 |
CRISPR-assisted detection of RNA–protein interactions in living cells W Yi, J Li, X Zhu, X Wang, L Fan, W Sun, L Liao, J Zhang, X Li, J Ye, ... Nature methods 17 (7), 685-688, 2020 | 91 | 2020 |
Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth K Dave, I Sur, J Yan, J Zhang, E Kaasinen, F Zhong, L Blaas, X Li, ... eLife 6, e23382, 2017 | 61 | 2017 |
The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression NQ Liu, M Ter Huurne, LN Nguyen, T Peng, SY Wang, JB Studd, O Joshi, ... Nature communications 8, 14418, 2017 | 58 | 2017 |
An array of 60,000 antibodies for proteome-scale antibody generation and target discovery Z Wang, Y Li, B Hou, MI Pronobis, M Wang, Y Wang, G Cheng, W Weng, ... Science advances 6 (11), eaax2271, 2020 | 28 | 2020 |
Characterization of the colorectal cancer–associated enhancer MYC-335 at 8q24: the role of rs67491583 S Tuupanen, J Yan, M Turunen, AE Gylfe, E Kaasinen, L Li, C Eng, ... Cancer genetics 205 (1-2), 25-33, 2012 | 28 | 2012 |
An atlas of the binding specificities of transcription factors in Pseudomonas aeruginosa directs prediction of novel regulators in virulence T Wang, W Sun, L Fan, C Hua, N Wu, S Fan, J Zhang, X Deng, J Yan eLife 10, e61885, 2021 | 24 | 2021 |
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development RJ Geusz, A Wang, J Chiou, JJ Lancman, N Wetton, S Kefalopoulou, ... eLife 10, e59067, 2021 | 23 | 2021 |