Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease JH Yun, A Lamb, R Chase, D Singh, MM Parker, A Saferali, J Vestbo, ... Journal of allergy and clinical immunology 141 (6), 2037-2047. e10, 2018 | 241 | 2018 |
JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome KL Del Bel, RJ Ragotte, A Saferali, S Lee, SM Vercauteren, SA Mostafavi, ... Journal of Allergy and Clinical Immunology 139 (6), 2016-2020. e5, 2017 | 140 | 2017 |
Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells H Yang, L Kozicky, A Saferali, SY Fung, N Afacan, B Cai, R Falsafi, E Gill, ... Biomaterials 111, 90-102, 2016 | 69 | 2016 |
RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking MM Parker, RP Chase, A Lamb, A Reyes, A Saferali, JH Yun, BE Himes, ... BMC medical genomics 10, 1-10, 2017 | 60 | 2017 |
Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions ME Martinez, M Charalambous, A Saferali, S Fiering, AK Naumova, ... Molecular Endocrinology 28 (11), 1875-1886, 2014 | 48 | 2014 |
Longer Telomere Length in COPD Patients with α1-Antitrypsin Deficiency Independent of Lung Function A Saferali, J Lee, DD Sin, FN Rouhani, ML Brantly, AJ Sandford PLoS One 9 (4), e95600, 2014 | 47 | 2014 |
Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease F Aminuddin, TL Hackett, D Stefanowicz, A Saferali, PD Paré, A Gulsvik, ... BMC pulmonary medicine 13, 1-10, 2013 | 39 | 2013 |
Cell culture-induced aberrant methylation of the imprinted IG DMR in human lymphoblastoid cell lines A Saferali, E Grundberg, S Berlivet, H Beauchemin, L Morcos, ... Epigenetics 5 (1), 50-60, 2010 | 39 | 2010 |
Polymorphisms associated with expression of BPIFA1/BPIFB1 and lung disease severity in cystic fibrosis A Saferali, M Obeidat, JC Bérubé, M Lamontagne, Y Bossé, M Laviolette, ... American journal of respiratory cell and molecular biology 53 (5), 607-614, 2015 | 36 | 2015 |
Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene A Saferali, JH Yun, MM Parker, P Sakornsakolpat, RP Chase, A Lamb, ... PLoS genetics 15 (7), e1008229, 2019 | 34 | 2019 |
Endoplasmic reticulum stress regulates chemokine production in cystic fibrosis airway cells through STAT3 modulation AC Tang, A Saferali, G He, AJ Sandford, LJ Strug, SE Turvey The Journal of Infectious Diseases, jiw516, 2016 | 33 | 2016 |
Nano‐enabled reposition of proton pump inhibitors for TLR inhibition: toward a new targeted nanotherapy for acute lung injury L Sun, Y Liu, X Liu, R Wang, J Gong, A Saferali, W Gao, A Ma, H Ma, ... Advanced Science 9 (3), 2104051, 2022 | 27 | 2022 |
Pulmonary arterial pruning and longitudinal change in percent emphysema and lung function: the genetic epidemiology of COPD study CL Pistenmaa, P Nardelli, SY Ash, CE Come, AA Diaz, FN Rahaghi, ... Chest 160 (2), 470-480, 2021 | 27 | 2021 |
Alpha-1 antitrypsin MZ heterozygosity is an endotype of chronic obstructive pulmonary disease AJ Ghosh, BD Hobbs, M Moll, A Saferali, A Boueiz, JH Yun, F Sciurba, ... American journal of respiratory and critical care medicine 205 (3), 313-323, 2022 | 26 | 2022 |
Development of a blood-based transcriptional risk score for chronic obstructive pulmonary disease M Moll, A Boueiz, AJ Ghosh, A Saferali, S Lee, Z Xu, JH Yun, BD Hobbs, ... American Journal of Respiratory and Critical Care Medicine 205 (2), 161-170, 2022 | 24 | 2022 |
A polygenic risk score for idiopathic pulmonary fibrosis and interstitial lung abnormalities M Moll, AL Peljto, JS Kim, H Xu, CL Debban, X Chen, A Menon, ... American Journal of Respiratory and Critical Care Medicine 208 (7), 791-801, 2023 | 23 | 2023 |
Genomics and response to long-term oxygen therapy in chronic obstructive pulmonary disease M Seo, W Qiu, W Bailey, GJ Criner, MT Dransfield, AL Fuhlbrigge, ... Journal of Molecular Medicine 96, 1375-1385, 2018 | 21 | 2018 |
Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis AJ Ghosh, BD Hobbs, JH Yun, A Saferali, M Moll, Z Xu, RP Chase, ... Respiratory research 23 (1), 97, 2022 | 19 | 2022 |
Characterization of a COPD-Associated NPNT Functional Splicing Genetic Variant in Human Lung Tissue via Long-Read Sequencing A Saferali, Z Xu, GM Sheynkman, CP Hersh, MH Cho, EK Silverman, ... MedRxiv, 2020.10. 20.20203927, 2020 | 19 | 2020 |
Immunomodulatory function of the cystic fibrosis modifier gene BPIFA1 A Saferali, AC Tang, LJ Strug, BS Quon, J Zlosnik, AJ Sandford, ... PLoS One 15 (1), e0227067, 2020 | 16 | 2020 |