| Measurement of regional myocardial blood flow with multiple colored microspheres. P Kowallik, R Schulz, BD Guth, A Schade, W Paffhausen, R Gross, ... Circulation 83 (3), 974-982, 1991 | 462 | 1991 |
| 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long … M Eckhardt, E Langkopf, M Mark, M Tadayyon, L Thomas, H Nar, ... Journal of medicinal chemistry 50 (26), 6450-6453, 2007 | 416 | 2007 |
| Recruitment of an inotropic reserve in moderately ischemic myocardium at the expense of metabolic recovery. A model of short-term hibernation. R Schulz, BD Guth, K Pieper, C Martin, G Heusch Circulation research 70 (6), 1282-1295, 1992 | 313 | 1992 |
| Ischemia of the dog heart induces the appearance of a cardiac mRNA coding for a protein with migration characteristics similar to heat-shock/stress protein 71. WH Dillmann, HB Mehta, A Barrieux, BD Guth, WE Neeley, J Ross Jr Circulation research 59 (1), 110-114, 1986 | 192 | 1986 |
| Mechanisms of augmented segment shortening in nonischemic areas during acute ischemia of the canine left ventricle. WY Lew, ZY Chen, B Guth, JW Covell Circulation research 56 (3), 351-358, 1985 | 184 | 1985 |
| 5-membered heterocycles, medicaments containing these compounds, their use and processes for their preparation G Linz, F Himmelsbach, H Pieper, V Austel, B Guth, J Weisenberger US Patent 5,817,677, 1998 | 174 | 1998 |
| Intracoronary alpha 2-adrenergic receptor blockade attenuates ischemia in conscious dogs during exercise. R Seitelberger, BD Guth, G Heusch, JD Lee, K Katayama, J Ross Jr Circulation research 62 (3), 436-442, 1988 | 170 | 1988 |
| Mechanism of beneficial effect of beta-adrenergic blockade on exercise-induced myocardial ischemia in conscious dogs. BD Guth, G Heusch, R Seitelberger, J Ross Jr Circulation research 60 (5), 738-746, 1987 | 166 | 1987 |
| Elimination of exercise-induced regional myocardial dysfunction by a bradycardiac agent in dogs with chronic coronary stenosis. BD Guth, G Heusch, R Seitelberger, J Ross Jr Circulation 75 (3), 661-669, 1987 | 142 | 1987 |
| Effects of isoflurane, ketamine-xylazine and a combination of medetomidine, midazolam and fentanyl on physiological variables continuously measured by telemetry in Wistar rats M Albrecht, J Henke, S Tacke, M Markert, B Guth BMC veterinary research 10, 1-14, 2014 | 140 | 2014 |
| Modulation of collateral artery growth in a porcine hindlimb ligation model using MCP-1 M Voskuil, N Van Royen, IE Hoefer, R Seidler, BD Guth, C Bode, ... American Journal of Physiology-Heart and Circulatory Physiology 284 (4 …, 2003 | 139 | 2003 |
| 3, 5-Dihydro-imidazo [4, 5-d] pyridazin-4-ones: a class of potent DPP-4 inhibitors M Eckhardt, N Hauel, F Himmelsbach, E Langkopf, H Nar, M Mark, ... Bioorganic & Medicinal Chemistry Letters 18 (11), 3158-3162, 2008 | 126 | 2008 |
| Mechanisms of improved ischemic regional dysfunction by bradycardia. Studies on UL-FS 49 in swine. C Indolfi, BD Guth, T Miura, S Miyazaki, R Schulz, J Ross Jr Circulation 80 (4), 983-993, 1989 | 117 | 1989 |
| Regional myocardial blood flow, function and metabolism using phosphorus-31 nuclear magnetic resonance spectroscopy during ischemia and reperfusion in dogs BD Guth, JF Martin, G Heusch, J Ross Jr Journal of the American College of Cardiology 10 (3), 673-681, 1987 | 115 | 1987 |
| Myocardial lactate release during ischemia in swine. Relation to regional blood flow. BD Guth, JA Wisneski, RA Neese, FC White, G Heusch, CD Mazer, ... Circulation 81 (6), 1948-1958, 1990 | 114 | 1990 |
| Attenuation of exercise-induced myocardial ischemia in dogs with recruitment of coronary vasodilator reserve by nifedipine. G Heusch, BD Guth, R Seitelberger, J Ross Jr Circulation 75 (2), 482-490, 1987 | 112 | 1987 |
| Preclinical cardiovascular risk assessment in modern drug development BD Guth Toxicological Sciences 97 (1), 4-20, 2007 | 106 | 2007 |
| Time course and mechanisms of contractile dysfunction during acute myocardial ischemia. BD Guth, R Schulz, G Heusch Circulation 87 (5 Suppl), IV35-42, 1993 | 100 | 1993 |
| Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: current recommendations from the Safety Pharmacology Society DJ Leishman, TW Beck, N Dybdal, DJ Gallacher, BD Guth, M Holbrook, ... Journal of Pharmacological and Toxicological Methods 65 (3), 93-101, 2012 | 98 | 2012 |
| Consequences of regional inotropic stimulation of ischemic myocardium on regional myocardial blood flow and function in anesthetized swine. R Schulz, S Miyazaki, M Miller, E Thaulow, G Heusch, J Ross Jr, BD Guth Circulation research 64 (6), 1116-1126, 1989 | 96 | 1989 |
