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Doug Crump
Doug Crump
Environment and Climate Change Canada
在 ec.gc.ca 的电子邮件经过验证
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引用次数
引用次数
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Adverse outcome pathway (AOP) development I: strategies and principles
DL Villeneuve, D Crump, N Garcia-Reyero, M Hecker, TH Hutchinson, ...
Toxicological Sciences 142 (2), 312-320, 2014
5812014
Adverse outcome pathway development II: best practices
DL Villeneuve, D Crump, N Garcia-Reyero, M Hecker, TH Hutchinson, ...
Toxicological Sciences 142 (2), 321-330, 2014
2332014
In Ovo Effects of Two Organophosphate Flame Retardants—TCPP and TDCPP—on Pipping Success, Development, mRNA Expression, and Thyroid Hormone …
A Farhat, D Crump, S Chiu, KL Williams, RJ Letcher, LT Gauthier, ...
toxicological sciences 134 (1), 92-102, 2013
2122013
Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis.
D Crump, K Werry, N Veldhoen, G Van Aggelen, CC Helbing
Environmental Health Perspectives 110 (12), 1199-1205, 2002
1992002
Rapid in vitro metabolism of the flame retardant triphenyl phosphate and effects on cytotoxicity and mRNA expression in chicken embryonic hepatocytes
G Su, D Crump, RJ Letcher, SW Kennedy
Environmental science & technology 48 (22), 13511-13519, 2014
1812014
Effects of tris (1, 3-dichloro-2-propyl) phosphate and tris (1-chloropropyl) phosphate on cytotoxicity and mRNA expression in primary cultures of avian hepatocytes and neuronal …
D Crump, S Chiu, SW Kennedy
Toxicological Sciences 126 (1), 140-148, 2012
1352012
Amino acid sequence of the ligand-binding domain of the aryl hydrocarbon receptor 1 predicts sensitivity of wild birds to effects of dioxin-like compounds
R Farmahin, GE Manning, D Crump, D Wu, LJ Mundy, SP Jones, ...
Toxicological Sciences 131 (1), 139-152, 2013
1162013
Use of an avian hepatocyte assay and the avian toxchip polymerse chain reaction array for testing prioritization of 16 organic flame retardants
E Porter, D Crump, C Egloff, S Chiu, SW Kennedy
Environmental toxicology and chemistry 33 (3), 573-582, 2014
972014
In Vitro Metabolism of the Flame Retardant Triphenyl Phosphate in Chicken Embryonic Hepatocytes and the Importance of the Hydroxylation Pathway
G Su, RJ Letcher, D Crump, DM Gooden, HM Stapleton
Environmental Science & Technology Letters 2 (4), 100-104, 2015
922015
Tris (1, 3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos
A Farhat, JK Buick, A Williams, CL Yauk, JM O'Brien, D Crump, ...
Toxicology and applied pharmacology 275 (2), 104-112, 2014
902014
In vitro and in ovo effects of four brominated flame retardants on toxicity and hepatic mRNA expression in chicken embryos
C Egloff, D Crump, S Chiu, G Manning, KK McLaren, CG Cassone, ...
Toxicology letters 207 (1), 25-33, 2011
782011
Expression Profiles of Novel Thyroid Hormone-Responsive Genes and Proteins in the Tail of Xenopus laevis Tadpoles Undergoing Precocious Metamorphosis
CC Helbing, K Werry, D Crump, D Domanski, N Veldhoen, CM Bailey
Molecular Endocrinology 17 (7), 1395-1409, 2003
782003
Sequence and in vitro function of chicken, ring-necked pheasant, and Japanese quail AHR1 predict in vivo sensitivity to dioxins
R Farmahin, D Wu, D Crump, JC Hervé, SP Jones, ME Hahn, SI Karchner, ...
Environmental science & technology 46 (5), 2967-2975, 2012
732012
In Ovo Effects of Perfluorohexane Sulfonate and Perfluorohexanoate on Pipping Success, Development, mRNA Expression, and Thyroid Hormone Levels in …
CG Cassone, V Vongphachan, S Chiu, KL Williams, RJ Letcher, ...
Toxicological Sciences 127 (1), 216-224, 2012
702012
Persistent, bioaccumulative, and toxic properties of liquid crystal monomers and their detection in indoor residential dust
H Su, S Shi, M Zhu, D Crump, RJ Letcher, JP Giesy, G Su
Proceedings of the National Academy of Sciences 116 (52), 26450-26458, 2019
672019
Organophosphate ester, 2-ethylhexyl diphenyl phosphate (EHDPP), elicits cytotoxic and transcriptomic effects in chicken embryonic hepatocytes and its biotransformation profile …
J Shen, Y Zhang, N Yu, D Crump, J Li, H Su, RJ Letcher, G Su
Environmental science & technology 53 (4), 2151-2160, 2019
602019
The effects of Dechlorane Plus on toxicity and mRNA expression in chicken embryos: a comparison of in vitro and in ovo approaches
D Crump, S Chiu, LT Gauthier, NJ Hickey, RJ Letcher, SW Kennedy
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2011
592011
Cytochrome P4501A Induction by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Two Chlorinated Dibenzofurans in Primary Hepatocyte Cultures of Three Avian Species
JC Hervé, D Crump, SP Jones, LJ Mundy, JP Giesy, MJ Zwiernik, ...
Toxicological sciences 113 (2), 380-391, 2010
562010
Distinctive gene profiles occur at key points during natural metamorphosis in the Xenopus laevis tadpole tail
N Veldhoen, D Crump, K Werry, CC Helbing
Developmental Dynamics: An Official Publication of the American Association …, 2002
552002
Effects of Hexabromocyclododecane and Polybrominated Diphenyl Ethers on mRNA Expression in Chicken (Gallus domesticus) Hepatocytes
D Crump, S Chiu, C Egloff, SW Kennedy
Toxicological sciences 106 (2), 479-487, 2008
532008
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