| Antiviral properties of chemical inhibitors of cellular anti-apoptotic Bcl-2 proteins D Bulanova, A Ianevski, A Bugai, Y Akimov, S Kuivanen, H Paavilainen, ... Viruses 9 (10), 271, 2017 | 48 | 2017 |
| Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer J Tang, P Gautam, A Gupta, L He, S Timonen, Y Akimov, W Wang, ... NPJ systems biology and applications 5 (1), 20, 2019 | 32 | 2019 |
| Orphan G protein-coupled receptor GPRC5A modulates integrin β1-mediated epithelial cell adhesion DR Bulanova, YA Akimov, A Rokka, TD Laajala, T Aittokallio, P Kouvonen, ... Cell adhesion & migration 11 (5-6), 434-446, 2017 | 22 | 2017 |
| Re-defining synthetic lethality by phenotypic profiling for precision oncology Y Akimov, T Aittokallio Cell chemical biology 28 (3), 246-256, 2021 | 21 | 2021 |
| Improved detection of differentially represented DNA barcodes for high‐throughput clonal phenomics Y Akimov, D Bulanova, S Timonen, K Wennerberg, T Aittokallio Molecular Systems Biology 16 (3), e9195, 2020 | 21 | 2020 |
| Chemical, physical and biological triggers of evolutionary conserved Bcl-xL-mediated apoptosis A Ianevski, E Kulesskiy, K Krpina, G Lou, Y Aman, A Bugai, K Aasumets, ... Cancers 12 (6), 1694, 2020 | 19 | 2020 |
| Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells A Jaiswal, G Peddinti, Y Akimov, K Wennerberg, S Kuznetsov, J Tang, ... Genome medicine 9, 1-15, 2017 | 17 | 2017 |
| Genetic and functional implications of an exonic TRIM55 variant in heart failure J Heliste, H Chheda, I Paatero, TA Salminen, Y Akimov, J Paavola, ... Journal of Molecular and Cellular Cardiology 138, 222-233, 2020 | 12 | 2020 |
| Multi‐modal meta‐analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor A Jaiswal, P Gautam, EA Pietilä, S Timonen, N Nordström, Y Akimov, ... Molecular systems biology 17 (3), e9526, 2021 | 10 | 2021 |
| CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau JC Polanco, Y Akimov, A Fernandes, A Briner, GR Hand, M van Roijen, ... Life Science Alliance 6 (1), 2023 | 6 | 2023 |
| DNA barcode-guided lentiviral CRISPRa tool to trace and isolate individual clonal lineages in heterogeneous cancer cell populations Y Akimov, D Bulanova, M Abyzova, K Wennerberg, T Aittokallio Biorxiv, 622506, 2019 | 6 | 2019 |
| Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple‑negative breast cancer. NPJ Syst Biol Appl. 2019; 5: 20 J Tang, P Gautam, A Gupta, L He, S Timonen, Y Akimov, W Wang, ... | 5 | |
| A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing drugs in RB1-deficient ovarian and breast cancer cells D Bulanova, Y Akimov, W Senkowski, J Oikkonen, L Gall-Mas, S Timonen, ... bioRxiv, 2022.11. 14.516369, 2022 | 2 | 2022 |
| A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells D Bulanova, Y Akimov, W Senkowski, J Oikkonen, L Gall-Mas, S Timonen, ... Science Advances 10 (21), eadj1564, 2024 | | 2024 |
| P1228: GENOME-WIDE CRISPR-CAS9 SCREENING IDENTIFIES THERAPEUTIC TARGETS FOR MATURE T-CELL MALIGNANCIES S Timonen, VR Gasparini, E Piekkari, O Dufva, S Awad, Y Akimov, ... HemaSphere 7 (S3), e0412416, 2023 | | 2023 |
| Genome-wide CRISPRi screening reveals regulators of Alzheimer’s tau pathology shared between exosomal and vesicle-free tau seeds JC Polanco, Y Akimov, A Fernandes, GR Hand, A Briner, M van Roijen, ... bioRxiv, 2022.04. 26.489622, 2022 | | 2022 |
| A method to identify physical, chemical and biological factors that trigger Bcl-xL-mediated apoptosis A Ianevski, E Kulesskiy, K Krpina, G Lou, Y Aman, A Bugai, K Aasumets, ... bioRxiv, 2020.01. 13.904714, 2020 | | 2020 |
| A novel exonic variant in TRIM55 gene predisposes to heart failure J Heliste, H Chheda, Y Akimov, I Paatero, K Elenius, T Aittokallio EUROPEAN HEART JOURNAL 40, 655-655, 2019 | | 2019 |
| 1179 A novel exonic variant in TRIM55 gene predisposes to heart failure J Heliste, H Chheda, Y Akimov, I Paatero, K Elenius, T Aittokallio European Heart Journal 40 (Supplement_1), ehz748. 0021, 2019 | | 2019 |
| Identification of internal tandem duplication within the FLT3 gene from AML patient next-generation sequence data Y Akimov, S Eldfors, D Malani, T Aittokallio, C Heckman Cancer Research 78 (13_Supplement), 3277-3277, 2018 | | 2018 |
