Therapeutic potential of an anti-HER2 single chain antibody–DM1 conjugates for the treatment of HER2-positive cancer H Zhang, Y Wang, Y Wu, X Jiang, Y Tao, Y Yao, Y Peng, X Chen, Y Fu, ... Signal transduction and targeted therapy 2 (1), 1-11, 2017 | 41 | 2017 |
Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site Q Lai, Y Wang, R Wang, W Lai, L Tang, Y Tao, Y Liu, R Zhang, L Huang, ... European Journal of Medicinal Chemistry 156, 162-179, 2018 | 32 | 2018 |
Promiximab-duocarmycin, a new CD56 antibody-drug conjugates, is highly efficacious in small cell lung cancer xenograft models L Yu, Y Lu, Y Yao, Y Liu, Y Wang, Q Lai, R Zhang, W Li, R Wang, Y Fu, ... Oncotarget 9 (4), 5197, 2018 | 32 | 2018 |
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice N Li, MB Torres, MR Spetz, R Wang, L Peng, M Tian, CM Dower, ... Cell Reports Medicine 2 (6), 2021 | 29 | 2021 |
Targeting of DDR1 with antibody‐drug conjugates has antitumor effects in a mouse model of colon carcinoma Y Tao, R Wang, Q Lai, M Wu, Y Wang, X Jiang, L Zeng, S Zhou, Z Li, ... Molecular Oncology 13 (9), 1855-1873, 2019 | 26 | 2019 |
Secreted protein acidic and rich in cysteine-like 1 suppresses metastasis in gastric stromal tumors C Shen, Y Yin, H Chen, R Wang, X Yin, Z Cai, B Zhang, Z Chen, Z Zhou BMC gastroenterology 18, 1-15, 2018 | 19 | 2018 |
Preparation and anti-cancer evaluation of promiximab-MMAE, an anti-CD56 antibody drug conjugate, in small cell lung cancer cell line xenograft models L Yu, Y Yao, Y Wang, S Zhou, Q Lai, Y Lu, Y Liu, R Zhang, R Wang, C Liu, ... Journal of Drug Targeting 26 (10), 905-912, 2018 | 17 | 2018 |
A novel 5T4-targeting antibody-drug conjugate H6-DM4 exhibits potent therapeutic efficacy in gastrointestinal tumor xenograft models R Wang, Q Lai, L Tang, Y Tao, Y Yao, Y Liu, Y Lu, C Shen, R Lu, C Fan, ... American journal of cancer research 8 (4), 610, 2018 | 17 | 2018 |
Cryptophycin-55/52 based antibody-drug conjugates: Synthesis, efficacy, and mode of action studies Q Lai, M Wu, R Wang, W Lai, Y Tao, Y Lu, Y Wang, L Yu, R Zhang, ... European Journal of Medicinal Chemistry 199, 112364, 2020 | 14 | 2020 |
Camel nanobody-based B7-H3 CAR-T cells show high efficacy against large solid tumours D Li, R Wang, T Liang, H Ren, C Park, CH Tai, W Ni, J Zhou, S Mackay, ... Nature Communications 14 (1), 5920, 2023 | 9 | 2023 |
Antibody heavy chain CDR3 length-dependent usage of human IGHJ4 and IGHJ6 germline genes H Wang, K Yan, R Wang, Y Yang, Y Shen, C Yu, L Chen Antibody Therapeutics 4 (2), 101-108, 2021 | 6 | 2021 |
HONG J, et al R FENG, R WANG Isolation of rabbit single domain antibodies to B7-H3 via protein immuni …, 2020 | 3 | 2020 |
Analysis of transcription profile to reveal altered signaling pathways following the overexpression of human desumoylating isopeptidase 2 in pancreatic cancer cells YY Fu, YH Kang, CC Shen, RX Wang, L Yu, XY Li, DD Cui, JL Yang, ... Oncology Letters 12 (6), 4677-4684, 2016 | 2 | 2016 |
CAMEL NANOBODY-BASED B7-H3 CAR-T CELLS WITH HIGH EFFICACY AGAINST SOLID TUMORS D Li, R Wang, T Liang, H Ren, C Park, CH Tai, W Ni, J Zhou, S Mackay, ... Antibody Therapeutics 6 (Supplement_1), tbad014. 005, 2023 | | 2023 |
IMMU-20. EVALUATION OF B7-H3 NANOBODY CAR-T CELLS IN PEDIATRIC GLIOBLASTOMA M Fanuzzi, A Cole, MP Singh, D Li, R Wang, T Liang, M Ho, A Nellan Neuro-Oncology 25 (Suppl 1), i53, 2023 | | 2023 |
High affinity nanobodies targeting b7-h3 (cd276) for treating multiple solid tumors M Ho, R Wang, BS Croix, D Li US Patent App. 17/770,940, 2022 | | 2022 |
Nanobody-based CAR T cells targeting B7-H3 in pancreatic cancer D Li, RX Wang, T Liang, BS Croix, M Ho Cancer Research 81 (13_Supplement), 1498-1498, 2021 | | 2021 |
Expression of 5T4 extracellular domain fusion protein and preparation of anti-5T4 monoclonal antibody with high affinity and internalization efficiency R Wang, Q Lai, Y Lu, Y Zhou, L Tang, Y Tao, Y Yao, L Yu, Y Liu, Y Wang, ... Protein Expression and Purification 158, 51-58, 2019 | | 2019 |