关注
Hua Su
Hua Su
Structural Chemistry, Merck & Co., Inc
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
DYW Lin, Y Tanaka, M Iwasaki, AG Gittis, HP Su, B Mikami, T Okazaki, ...
Proceedings of the National Academy of Sciences 105 (8), 3011-3016, 2008
5292008
Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)
HP Su, K Nakada-Tsukui, AC Tosello-Trampont, Y Li, G Bu, PM Henson, ...
Journal of Biological Chemistry 277 (14), 11772-11779, 2002
2852002
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities
A Sette, M Moutaftsi, J Moyron-Quiroz, MM McCausland, DH Davies, ...
Immunity 28 (6), 847-858, 2008
2152008
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors
HP Su, Y Yan, GS Prasad, RF Smith, CL Daniels, PD Abeywickrema, ...
Journal of virology 84 (15), 7625-7633, 2010
1162010
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine
MREI Benhnia, MM McCausland, HP Su, K Singh, J Hoffmann, DH Davies, ...
Journal of virology 82 (7), 3751-3768, 2008
1052008
Essential role for the C-terminal noncatalytic region of SHIP in FcγRIIB1-mediated inhibitory signaling
MJ Aman, SF Walk, ME March, HP Su, DJ Carver, KS Ravichandran
Molecular and cellular biology 20 (10), 3576-3589, 2000
862000
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein
A Tang, Z Chen, KS Cox, HP Su, C Callahan, A Fridman, L Zhang, ...
Nature communications 10 (1), 4153, 2019
832019
Discovery of 1-Amino-5H-pyrido[4,3-b]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders
J Lim, B Taoka, RD Otte, K Spencer, CJ Dinsmore, MD Altman, G Chan, ...
Journal of medicinal chemistry 54 (20), 7334-7349, 2011
822011
The 1.51-Å structure of the poxvirus L1 protein, a target of potent neutralizing antibodies
HP Su, SC Garman, TJ Allison, C Fogg, B Moss, DN Garboczi
Proceedings of the National Academy of Sciences 102 (12), 4240-4245, 2005
812005
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
AK Saxena, K Singh, HP Su, MM Klein, AW Stowers, AJ Saul, CA Long, ...
Nature structural & molecular biology 13 (1), 90-91, 2006
772006
Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain
SJ Stachel, JM Sanders, DA Henze, MT Rudd, HP Su, Y Li, KK Nanda, ...
Journal of Medicinal Chemistry 57 (13), 5800-5816, 2014
762014
The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure
MM Klein, AG Gittis, HP Su, MO Makobongo, JM Moore, S Singh, ...
PLoS pathogens 4 (9), e1000147, 2008
652008
Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication
D Camerini, HP Su, G Gamez-Torre, ML Johnson, JA Zack, ISY Chen
Journal of virology 74 (7), 3196-3204, 2000
642000
Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein
HP Su, JW Golden, AG Gittis, JW Hooper, DN Garboczi
Virology 368 (2), 331-341, 2007
572007
Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells
HP Su, E Brugnera, W Van Criekinge, E Smits, M Hengartner, T Bogaert, ...
Journal of Biological Chemistry 275 (13), 9542-9549, 2000
572000
Structural characterization of nonactive site, TrkA-selective kinase inhibitors
HP Su, K Rickert, C Burlein, K Narayan, M Bukhtiyarova, DM Hurzy, ...
Proceedings of the National Academy of Sciences 114 (3), E297-E306, 2017
472017
The structure of the poxvirus A33 protein reveals a dimer of unique C-type lectin-like domains
HP Su, K Singh, AG Gittis, DN Garboczi
Journal of virology 84 (5), 2502-2510, 2010
452010
Design and synthesis of piperazine sulfonamide cores leading to highly potent HIV-1 protease inhibitors
CJ Bungard, PD Williams, J Schulz, CM Wiscount, MK Holloway, ...
ACS medicinal chemistry letters 8 (12), 1292-1297, 2017
432017
The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-glucose
K Singh, AG Gittis, RK Gitti, SA Ostazeski, HP Su, DN Garboczi
Journal of virology 90 (10), 5020-5030, 2016
422016
Structure of human prostasin, a target for the regulation of hypertension
KW Rickert, P Kelley, NJ Byrne, RE Diehl, DL Hall, AM Montalvo, JC Reid, ...
Journal of Biological Chemistry 283 (50), 34864-34872, 2008
392008
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