Principal pathway coupling agonist binding to channel gating in nicotinic receptors WY Lee, SM Sine Nature 438 (7065), 243-247, 2005 | 303 | 2005 |
Detection and trapping of intermediate states priming nicotinic receptor channel opening N Mukhtasimova, WY Lee, HL Wang, SM Sine Nature 459 (7245), 451-454, 2009 | 240 | 2009 |
Binding to gating transduction in nicotinic receptors: Cys-loop energetically couples to pre-M1 and M2–M3 regions WY Lee, CR Free, SM Sine Journal of Neuroscience 29 (10), 3189-3199, 2009 | 108 | 2009 |
A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors CS Walker, S Jensen, M Ellison, JA Matta, WY Lee, JS Imperial, N Duclos, ... Current Biology 19 (11), 900-908, 2009 | 81 | 2009 |
Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating SM Sine, XM Shen, HL Wang, K Ohno, WY Lee, A Tsujino, J Brengmann, ... The Journal of general physiology 120 (4), 483, 2002 | 70 | 2002 |
Nicotinic receptor interloop proline anchors β1-β2 and Cys loops in coupling agonist binding to channel gating WY Lee, CR Free, SM Sine The Journal of general physiology 132 (2), 265, 2008 | 53 | 2008 |
Invariant aspartic acid in muscle nicotinic receptor contributes selectively to the kinetics of agonist binding WY Lee, SM Sine The Journal of general physiology 124 (5), 555, 2004 | 49 | 2004 |
Prevention of anti-microbial peptide LL-37-induced apoptosis and ATP release in the urinary bladder by a modified glycosaminoglycan WY Lee, JR Savage, J Zhang, W Jia, S Oottamasathien, GD Prestwich PloS one 8 (10), e77854, 2013 | 38 | 2013 |
A modified glycosaminoglycan, GM-0111, inhibits molecular signaling involved in periodontitis JR Savage, A Pulsipher, NV Rao, TP Kennedy, GD Prestwich, ME Ryan, ... PLoS One 11 (6), e0157310, 2016 | 29 | 2016 |
Physiological relevance of LL-37 induced bladder inflammation and mast cells S Oottamasathien, W Jia, LMC Roundy, J Zhang, L Wang, X Ye, AC Hill, ... The Journal of urology 190 (4), 1596-1602, 2013 | 18 | 2013 |
A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis JA Alt, WY Lee, BM Davis, JR Savage, TP Kennedy, GD Prestwich, ... PLoS One 13 (9), e0204709, 2018 | 17 | 2018 |
Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate D Madan, CG Ferguson, WY Lee, GD Prestwich, CA Testa PloS one 8 (11), e79065, 2013 | 17 | 2013 |
Mechanistic diversity underlying fast channel congenital myasthenic syndromes SM Sine, HAIL WANG, K Ohno, XINM SHEN, WY Lee, AG Engel Annals of the New York Academy of Sciences 998 (1), 128-137, 2003 | 16 | 2003 |
Behavioral changes with alterations of choline acetyltransferase immunoreactivities induced by N-butyl benzenesulfonamide. WY Lee, SJ Hwang, DH Cho, JS Kim Veterinary and human toxicology 37 (6), 537-542, 1995 | 15 | 1995 |
Toxicities of 166Holmium-chitosan in mice. WY Lee, EY Moon, J Lee, CH Choi, SC Nam, KB Park, JM Ryu, YH Chung, ... Arzneimittel-Forschung 48 (3), 300-304, 1998 | 13 | 1998 |
GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling A Pulsipher, JR Savage, TP Kennedy, K Gupta, BG Cuiffo, ST Sonis, ... PLoS One 16 (3), e0249343, 2021 | 10 | 2021 |
Synthesis, pharmacokinetics, and biological activity of a series of new pyridonecarboxylic acid antibacterial agents bearing a 5‐fluoro‐2‐pyridyl group or a 3‐fluoro‐4‐pyridyl … SJ Yoon, YH Chung, CW Lee, YS Oh, DR Choi, ND Kim, JK Lim, YH Jin, ... Journal of heterocyclic chemistry 34 (3), 1021-1027, 1997 | 10 | 1997 |
Methods for treating or preventing urological inflammation G Prestwich, S Oottamasathien, W Jia, L McCoard, WY Lee US Patent 9,522,162, 2016 | 3 | 2016 |
Recent structural and mechanistic insights into endplate acetylcholine receptors SM Sine, F Gao, WY Lee, N Mukhtasimova, HL Wang, AG Engel Annals of the New York Academy of Sciences 1132 (1), 53-60, 2008 | 2 | 2008 |
The neurotoxicological alterations induced by narcotic drugs and industrial chemicals in the rat are associated with quantitative changes in glial fibrillary acidic protein DH Cho, Y Jeong, JG Kim, BH Lee, SJ Hwang, WY Lee, JG Kim, TS Cho, ... Toxicological Research 11 (2), 315-327, 1995 | 2 | 1995 |