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Won Yong Lee
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年份
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
WY Lee, SM Sine
Nature 438 (7065), 243-247, 2005
3032005
Detection and trapping of intermediate states priming nicotinic receptor channel opening
N Mukhtasimova, WY Lee, HL Wang, SM Sine
Nature 459 (7245), 451-454, 2009
2402009
Binding to gating transduction in nicotinic receptors: Cys-loop energetically couples to pre-M1 and M2–M3 regions
WY Lee, CR Free, SM Sine
Journal of Neuroscience 29 (10), 3189-3199, 2009
1082009
A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors
CS Walker, S Jensen, M Ellison, JA Matta, WY Lee, JS Imperial, N Duclos, ...
Current Biology 19 (11), 900-908, 2009
812009
Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating
SM Sine, XM Shen, HL Wang, K Ohno, WY Lee, A Tsujino, J Brengmann, ...
The Journal of general physiology 120 (4), 483, 2002
702002
Nicotinic receptor interloop proline anchors β1-β2 and Cys loops in coupling agonist binding to channel gating
WY Lee, CR Free, SM Sine
The Journal of general physiology 132 (2), 265, 2008
532008
Invariant aspartic acid in muscle nicotinic receptor contributes selectively to the kinetics of agonist binding
WY Lee, SM Sine
The Journal of general physiology 124 (5), 555, 2004
492004
Prevention of anti-microbial peptide LL-37-induced apoptosis and ATP release in the urinary bladder by a modified glycosaminoglycan
WY Lee, JR Savage, J Zhang, W Jia, S Oottamasathien, GD Prestwich
PloS one 8 (10), e77854, 2013
382013
A modified glycosaminoglycan, GM-0111, inhibits molecular signaling involved in periodontitis
JR Savage, A Pulsipher, NV Rao, TP Kennedy, GD Prestwich, ME Ryan, ...
PLoS One 11 (6), e0157310, 2016
292016
Physiological relevance of LL-37 induced bladder inflammation and mast cells
S Oottamasathien, W Jia, LMC Roundy, J Zhang, L Wang, X Ye, AC Hill, ...
The Journal of urology 190 (4), 1596-1602, 2013
182013
A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis
JA Alt, WY Lee, BM Davis, JR Savage, TP Kennedy, GD Prestwich, ...
PLoS One 13 (9), e0204709, 2018
172018
Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate
D Madan, CG Ferguson, WY Lee, GD Prestwich, CA Testa
PloS one 8 (11), e79065, 2013
172013
Mechanistic diversity underlying fast channel congenital myasthenic syndromes
SM Sine, HAIL WANG, K Ohno, XINM SHEN, WY Lee, AG Engel
Annals of the New York Academy of Sciences 998 (1), 128-137, 2003
162003
Behavioral changes with alterations of choline acetyltransferase immunoreactivities induced by N-butyl benzenesulfonamide.
WY Lee, SJ Hwang, DH Cho, JS Kim
Veterinary and human toxicology 37 (6), 537-542, 1995
151995
Toxicities of 166Holmium-chitosan in mice.
WY Lee, EY Moon, J Lee, CH Choi, SC Nam, KB Park, JM Ryu, YH Chung, ...
Arzneimittel-Forschung 48 (3), 300-304, 1998
131998
GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling
A Pulsipher, JR Savage, TP Kennedy, K Gupta, BG Cuiffo, ST Sonis, ...
PLoS One 16 (3), e0249343, 2021
102021
Synthesis, pharmacokinetics, and biological activity of a series of new pyridonecarboxylic acid antibacterial agents bearing a 5‐fluoro‐2‐pyridyl group or a 3‐fluoro‐4‐pyridyl …
SJ Yoon, YH Chung, CW Lee, YS Oh, DR Choi, ND Kim, JK Lim, YH Jin, ...
Journal of heterocyclic chemistry 34 (3), 1021-1027, 1997
101997
Methods for treating or preventing urological inflammation
G Prestwich, S Oottamasathien, W Jia, L McCoard, WY Lee
US Patent 9,522,162, 2016
32016
Recent structural and mechanistic insights into endplate acetylcholine receptors
SM Sine, F Gao, WY Lee, N Mukhtasimova, HL Wang, AG Engel
Annals of the New York Academy of Sciences 1132 (1), 53-60, 2008
22008
The neurotoxicological alterations induced by narcotic drugs and industrial chemicals in the rat are associated with quantitative changes in glial fibrillary acidic protein
DH Cho, Y Jeong, JG Kim, BH Lee, SJ Hwang, WY Lee, JG Kim, TS Cho, ...
Toxicological Research 11 (2), 315-327, 1995
21995
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