| mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ... Nature cell biology 17 (9), 1205-1217, 2015 | 680 | 2015 |
| NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumors K Ford, CJ Hanley, M Mellone, C Szyndralewiez, F Heitz, P Wiesel, ... Cancer research 80 (9), 1846-1860, 2020 | 219 | 2020 |
| Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer J Clarke, B Panwar, A Madrigal, D Singh, R Gujar, O Wood, SJ Chee, ... Journal of Experimental Medicine 216 (9), 2128-2149, 2019 | 197 | 2019 |
| A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers CJ Hanley, F Noble, M Ward, M Bullock, C Drifka, M Mellone, ... Oncotarget 7 (5), 6159, 2016 | 188 | 2016 |
| PTBP1-mediated alternative splicing regulates the inflammatory secretome and the pro-tumorigenic effects of senescent cells A Georgilis, S Klotz, CJ Hanley, N Herranz, B Weirich, B Morancho, ... Cancer cell 34 (1), 85-102. e9, 2018 | 187 | 2018 |
| Targeting the myofibroblastic cancer-associated fibroblast phenotype through inhibition of NOX4 CJ Hanley, M Mellone, K Ford, SM Thirdborough, T Mellows, SJ Frampton, ... JNCI: Journal of the National Cancer Institute 110 (1), 109-120, 2018 | 169 | 2018 |
| Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis M Mellone, CJ Hanley, S Thirdborough, T Mellows, E Garcia, J Woo, ... Aging (Albany NY) 9 (1), 114, 2017 | 118 | 2017 |
| Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy S Eschweiler, J Clarke, C Ramírez-Suástegui, B Panwar, A Madrigal, ... Nature immunology 22 (8), 1052-1063, 2021 | 78 | 2021 |
| An optimised tissue disaggregation and data processing pipeline for characterising fibroblast phenotypes using single-cell RNA sequencing S Waise, R Parker, MJJ Rose-Zerilli, DM Layfield, O Wood, J West, ... Scientific reports 9 (1), 9580, 2019 | 49 | 2019 |
| Cancer-associated fibroblasts in oral cancer: a current perspective on function and potential for therapeutic targeting KJ Bienkowska, CJ Hanley, GJ Thomas Frontiers in Oral Health 2, 686337, 2021 | 40 | 2021 |
| Tumor-resident stromal cells promote breast cancer invasion through regulation of the basal phenotype CJ Hanley, E Henriet, OK Sirka, GJ Thomas, AJ Ewald Molecular Cancer Research 18 (11), 1615-1622, 2020 | 39 | 2020 |
| Pro‐migratory and TGF‐β‐activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8‐dependent GTPase switch J Tod, CJ Hanley, MR Morgan, M Rucka, T Mellows, MA Lopez, P Kiely, ... The Journal of pathology 243 (1), 37-50, 2017 | 33 | 2017 |
| Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer CJ Hanley, S Waise, MJ Ellis, MA Lopez, WY Pun, J Taylor, R Parker, ... Nature communications 14 (1), 387, 2023 | 31 | 2023 |
| Targeting cancer-associated fibroblasts: Challenges, opportunities and future directions BH Jenkins, JF Buckingham, CJ Hanley, GJ Thomas Pharmacology & Therapeutics 240, 108231, 2022 | 28 | 2022 |
| T-cell tumour exclusion and immunotherapy resistance: a role for CAF targeting CJ Hanley, GJ Thomas British journal of cancer 123 (9), 1353-1355, 2020 | 28 | 2020 |
| Targeting cancer associated fibroblasts to enhance immunotherapy: emerging strategies and future perspectives CJ Hanley, GJ Thomas Oncotarget 12 (14), 1427, 2021 | 22 | 2021 |
| CD4+ follicular helper-like T cells are key players in anti-tumor immunity D Singh, AP Ganesan, B Panwar, S Eschweiler, CJ Hanley, A Madrigal, ... bioRxiv, 2020.01. 08.898346, 2020 | 15 | 2020 |
| Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ... Nature cell biology 17 (10), 1370, 2015 | 15 | 2015 |
| ATM Regulates differentiation of myofibroblastic cancer-associated fibroblasts and can be targeted to overcome immunotherapy resistance M Mellone, K Piotrowska, G Venturi, L James, A Bzura, MA Lopez, ... Cancer Research 82 (24), 4571-4585, 2022 | 12 | 2022 |
| Spatially discrete signalling niches regulate fibroblast heterogeneity in human lung cancer CJ Hanley, S Waise, R Parker, MA Lopez, J Taylor, LM Kimbley, J West, ... bioRxiv, 2020.06. 08.134270, 2020 | 8 | 2020 |
