The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy R Knöll, M Hoshijima, HM Hoffman, V Person, I Lorenzen-Schmidt, ... Cell 111 (7), 943-955, 2002 | 942 | 2002 |
Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy T Hayashi, T Arimura, M Itoh-Satoh, K Ueda, S Hohda, N Inagaki, ... Journal of the American College of Cardiology 44 (11), 2192-2201, 2004 | 357 | 2004 |
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure A Chokshi, K Drosatos, FH Cheema, R Ji, T Khawaja, S Yu, T Kato, ... Circulation 125 (23), 2844-2853, 2012 | 277 | 2012 |
Laminin-α4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells R Knöll, R Postel, J Wang, R Krätzner, G Hennecke, AM Vacaru, ... Circulation 116 (5), 515-525, 2007 | 260 | 2007 |
Anisotropic stretch‐induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers SM Gopalan, C Flaim, SN Bhatia, M Hoshijima, R Knoell, KR Chien, ... Biotechnology and bioengineering 81 (5), 578-587, 2003 | 235 | 2003 |
Asymmetric septal hypertrophy in heterozygous cMyBP-C null mice L Carrier, R Knöll, N Vignier, DI Keller, P Bausero, B Prudhon, R Isnard, ... Cardiovascular research 63 (2), 293-304, 2004 | 165 | 2004 |
The sarcomeric Z‐disc and Z‐discopathies R Knöll, B Buyandelger, M Lab BioMed Research International 2011 (1), 569628, 2011 | 152 | 2011 |
Cardiac mechanotransduction and implications for heart disease R Knöll, M Hoshijima, K Chien Journal of molecular medicine 81, 750-756, 2003 | 132 | 2003 |
Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology G Tarone, JL Balligand, J Bauersachs, A Clerk, L De Windt, S Heymans, ... European journal of heart failure 16 (5), 494-508, 2014 | 128 | 2014 |
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin–ECM adhesion complex R Postel, P Vakeel, J Topczewski, R Knöll, J Bakkers Developmental biology 318 (1), 92-101, 2008 | 123 | 2008 |
A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy R Knöll, S Kostin, S Klede, K Savvatis, L Klinge, I Stehle, S Gunkel, ... Circulation research 106 (4), 695-704, 2010 | 119 | 2010 |
Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation RS Khan, TS Kato, A Chokshi, M Chew, S Yu, C Wu, P Singh, FH Cheema, ... Circulation: Heart Failure 5 (3), 340-348, 2012 | 107 | 2012 |
Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart R Knöll, WA Linke, P Zou, S Miočiċ, S Kostin, B Buyandelger, CH Ku, ... Circulation research 109 (7), 758-769, 2011 | 98 | 2011 |
OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency S Marston, C Montgiraud, AB Munster, ON Copeland, O Choi, ... PLoS One 10 (9), e0138568, 2015 | 94 | 2015 |
MLP (muscle LIM protein) as a stress sensor in the heart B Buyandelger, KE Ng, S Miocic, I Piotrowska, S Gunkel, CH Ku, R Knöll Pflügers Archiv-European Journal of Physiology 462, 135-142, 2011 | 83 | 2011 |
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model A Carreras, LS Pane, R Nitsch, K Madeyski-Bengtson, M Porritt, ... BMC biology 17, 1-14, 2019 | 82 | 2019 |
Relevance of Brain Natriuretic Peptide in Preload-Dependent Regulation of Cardiac Sarcoplasmic Reticulum Ca2+ ATPase Expression H Kögler, P Schott, K Toischer, H Milting, PN Van, M Kohlhaas, C Grebe, ... Circulation 113 (23), 2724-2732, 2006 | 80 | 2006 |
Expression of heat shock proteins in the normal and stunned porcine myocardium J Andres, HS Sharma, R Knöll, J Stahl, LMA Sassen, PD Verdouw, ... Cardiovascular research 27 (8), 1421-1429, 1993 | 75 | 1993 |
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations A Fomin, A Gärtner, L Cyganek, M Tiburcy, I Tuleta, L Wellers, L Folsche, ... Science translational medicine 13 (618), eabd3079, 2021 | 74 | 2021 |
Towards a re‐definition of ‘cardiac hypertrophy’through a rational characterization of left ventricular phenotypes: a position paper of the Working Group ‘Myocardial Function … R Knöll, G Iaccarino, G Tarone, D Hilfiker‐Kleiner, J Bauersachs, ... European journal of heart failure 13 (8), 811-819, 2011 | 74 | 2011 |