LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface G Malojčić, D Andres, M Grabowicz, AH George, N Ruiz, TJ Silhavy, ... Proceedings of the National Academy of Sciences 111 (26), 9467-9472, 2014 | 112 | 2014 |
Structural basis of substrate specificity of human oligosaccharyl transferase subunit N33/Tusc3 and its role in regulating protein N-glycosylation E Mohorko, RL Owen, G Malojčić, MS Brozzo, M Aebi, R Glockshuber Structure 22 (4), 590-601, 2014 | 97 | 2014 |
DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli JPA Grimshaw, CU Stirnimann, MS Brozzo, G Malojcic, MG Grütter, ... Journal of molecular biology 380 (4), 667-680, 2008 | 92 | 2008 |
A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa G Andolina, LC Bencze, K Zerbe, M Müller, J Steinmann, H Kocherla, ... ACS chemical biology 13 (3), 666-675, 2018 | 88 | 2018 |
A novel bis-phenanthridine triamine with pH controlled binding to nucleotides and nucleic acids G Malojčić, I Piantanida, M Marinić, M Žinić, M Marjanović, M Kralj, ... Organic & biomolecular chemistry 3 (24), 4373-4381, 2005 | 70 | 2005 |
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription JK Rimel, ZC Poss, B Erickson, ZL Maas, CC Ebmeier, JL Johnson, ... Genes & development 34 (21-22), 1452-1473, 2020 | 68 | 2020 |
A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli G Malojčić, RL Owen, JPA Grimshaw, MS Brozzo, H Dreher-Teo, ... Proceedings of the National Academy of Sciences 105 (49), 19217-19222, 2008 | 66 | 2008 |
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents D Vinayagam, D Quentin, J Yu-Strzelczyk, O Sitsel, F Merino, M Stabrin, ... Elife 9, e60603, 2020 | 57 | 2020 |
Discovery of SY-5609: a selective, noncovalent inhibitor of CDK7 JJ Marineau, KB Hamman, S Hu, S Alnemy, J Mihalich, A Kabro, ... Journal of Medicinal Chemistry 65 (2), 1458-1480, 2021 | 54 | 2021 |
Oxidative folding of peptides and proteins L Moroder, J Buchner Royal society of chemistry, 2009 | 53* | 2009 |
Discovery of a potent and selective TRPC5 inhibitor, efficacious in a focal segmental glomerulosclerosis model M Yu, MW Ledeboer, M Daniels, G Malojcic, TT Tibbitts, M Coeffet-Le Gal, ... ACS Medicinal Chemistry Letters 10 (11), 1579-1585, 2019 | 47 | 2019 |
The PAPS-independent aryl sulfotransferase and the alternative disulfide bond formation system in pathogenic bacteria G Malojčić, R Glockshuber Antioxidants & redox signaling 13 (8), 1247-1259, 2010 | 45 | 2010 |
Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB G Malojčić, RL Owen, JPA Grimshaw, R Glockshuber FEBS letters 582 (23-24), 3301-3307, 2008 | 43 | 2008 |
Structural and mechanistic insights into the PAPS-independent sulfotransfer catalyzed by bacterial aryl sulfotransferase and the role of the DsbL/DsbI system in its folding G Malojcic, RL Owen, R Glockshuber Biochemistry 53 (11), 1870-1877, 2014 | 30 | 2014 |
A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface M Grabowicz, D Andres, MD Lebar, G Malojčić, D Kahne, TJ Silhavy Elife 3, e05334, 2014 | 28 | 2014 |
Discovery and optimization of highly selective inhibitors of CDK5 MH Daniels, G Malojcic, SL Clugston, B Williams, M Coeffet-Le Gal, ... Journal of Medicinal Chemistry 65 (4), 3575-3596, 2022 | 19 | 2022 |
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic AD Westerling-Bui, EM Fast, TW Soare, S Venkatachalan, M DeRan, ... Science Advances 8 (27), eabj5633, 2022 | 17 | 2022 |
A peptidomimetic antibiotic interacts with the periplasmic domain of LptD from Pseudomonas aeruginosa. ACS Chem Biol 13: 666–675 G Andolina, LC Bencze, K Zerbe, M Muller, J Steinmann, H Kocherla, ... | 9 | 2018 |
Mechanism of the prokaryotic transmembrane disulfide reduction pathway and its in vitro reconstitution from purified components G Malojčić, ER Geertsma, MS Brozzo, R Glockshuber Angewandte Chemie International Edition 51 (28), 6900-6903, 2012 | 5 | 2012 |
A translational kidney organoid system bolsters human relevance of clinical development candidate A Westerling-Bui, TW Soare, S Venkatachalan, M DeRan, EM Fast, ... bioRxiv, 2019.12. 30.891440, 2019 | 4 | 2019 |