Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis HB Kordasiewicz, LM Stanek, EV Wancewicz, C Mazur, MM McAlonis, ... Neuron 74 (6), 1031-1044, 2012 | 859 | 2012 |
Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories SA Heldt, L Stanek, JP Chhatwal, KJ Ressler Molecular psychiatry 12 (7), 656-670, 2007 | 839 | 2007 |
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy MA Passini, J Bu, AM Richards, C Kinnecom, SP Sardi, LM Stanek, Y Hua, ... Science translational medicine 3 (72), 72ra18-72ra18, 2011 | 573 | 2011 |
Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning LM Rattiner, M Davis, CT French, KJ Ressler Journal of Neuroscience 24 (20), 4796-4806, 2004 | 430 | 2004 |
CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy SP Sardi, J Clarke, C Kinnecom, TJ Tamsett, L Li, LM Stanek, MA Passini, ... Proceedings of the National Academy of Sciences 108 (29), 12101-12106, 2011 | 345 | 2011 |
Amygdala BDNF signaling is required for consolidation but not encoding of extinction JP Chhatwal, L Stanek-Rattiner, M Davis, KJ Ressler Nature neuroscience 9 (7), 870-872, 2006 | 288 | 2006 |
Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease LM Stanek, SP Sardi, B Mastis, AR Richards, CM Treleaven, T Taksir, ... Human gene therapy 25 (5), 461-474, 2014 | 186 | 2014 |
Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice MA Pouladi, LM Stanek, Y Xie, S Franciosi, AL Southwell, Y Deng, ... Human molecular genetics 21 (10), 2219-2232, 2012 | 177 | 2012 |
Brain-derived neurotrophic factor in amygdala-dependent learning LM Rattiner, M Davis, KJ Ressler The Neuroscientist 11 (4), 323-333, 2005 | 173 | 2005 |
Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning LM Rattiner, M Davis, KJ Ressler Learning & memory 11 (6), 727-731, 2004 | 170 | 2004 |
Cocaine-and amphetamine related transcript (CART) and anxiety LM Stanek Peptides 27 (8), 2005-2011, 2006 | 75 | 2006 |
Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease LM Stanek, W Yang, S Angus, PS Sardi, MR Hayden, GH Hung, ... Journal of Huntington's disease 2 (2), 217-228, 2013 | 73 | 2013 |
Extensive transduction and enhanced spread of a modified AAV2 capsid in the non-human primate CNS J Naidoo, LM Stanek, K Ohno, S Trewman, L Samaranch, P Hadaczek, ... Molecular Therapy 26 (10), 2418-2430, 2018 | 63 | 2018 |
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice BKY Wong, DE Ehrnhoefer, RK Graham, DDO Martin, S Ladha, V Uribe, ... Neurobiology of disease 76, 24-36, 2015 | 63 | 2015 |
Differential brain-derived neurotrophic factor expression in limbic brain regions following social defeat or territorial aggression. SL Taylor, LM Stanek, KJ Ressler, KL Huhman Behavioral neuroscience 125 (6), 911, 2011 | 60 | 2011 |
Group II metabotropic glutamate receptors within the amygdala regulate fear as assessed with potentiated startle in rats. DL Walker, LM Rattiner, M Davis Behavioral neuroscience 116 (6), 1075, 2002 | 60 | 2002 |
Differential regional expression of brain-derived neurotrophic factor following olfactory fear learning SV Jones, L Stanek-Rattiner, M Davis, KJ Ressler Learning & memory 14 (12), 816-820, 2007 | 50 | 2007 |
Studies of cocaine-and amphetamine-regulated transcript (CART) knockout mice M Moffett, L Stanek, J Harley, G Rogge, M Asnicar, H Hsiung, M Kuhar Peptides 27 (8), 2037-2045, 2006 | 48 | 2006 |
Widespread AAV1-and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease P Hadaczek, L Stanek, A Ciesielska, V Sudhakar, L Samaranch, ... Molecular Therapy Methods & Clinical Development 3, 2016 | 46 | 2016 |
Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain JA Sullivan, LM Stanek, MJ Lukason, J Bu, SR Osmond, EA Barry, ... Gene Therapy 25 (3), 205-219, 2018 | 29 | 2018 |