Designed to penetrate: time-resolved interaction of single antibiotic molecules with bacterial pores EM Nestorovich, C Danelon, M Winterhalter, SM Bezrukov Proceedings of the National Academy of Sciences 99 (15), 9789-9794, 2002 | 390 | 2002 |
Salting out the ionic selectivity of a wide channel: the asymmetry of OmpF A Alcaraz, EM Nestorovich, M Aguilella-Arzo, VM Aguilella, SM Bezrukov Biophysical journal 87 (2), 943-957, 2004 | 200 | 2004 |
Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation C Danelon, EM Nestorovich, M Winterhalter, M Ceccarelli, SM Bezrukov Biophysical journal 90 (5), 1617-1627, 2006 | 196 | 2006 |
Residue ionization and ion transport through OmpF channels EM Nestorovich, TK Rostovtseva, SM Bezrukov Biophysical Journal 85 (6), 3718-3729, 2003 | 196 | 2003 |
Partitioning of differently sized poly (ethylene glycol) s into OmpF porin TK Rostovtseva, EM Nestorovich, SM Bezrukov Biophysical journal 82 (1), 160-169, 2002 | 147 | 2002 |
Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design VA Karginov, EM Nestorovich, M Moayeri, SH Leppla, SM Bezrukov Proceedings of the National Academy of Sciences 102 (42), 15075-15080, 2005 | 146 | 2005 |
Pseudomonas aeruginosa porin OprF exists in two different conformations E Sugawara, EM Nestorovich, SM Bezrukov, H Nikaido Journal of Biological Chemistry 281 (24), 16220-16229, 2006 | 127 | 2006 |
Syringomycin E channel: a lipidic pore stabilized by lipopeptide? VV Malev, LV Schagina, PA Gurnev, JY Takemoto, EM Nestorovich, ... Biophysical journal 82 (4), 1985-1994, 2002 | 107 | 2002 |
Inhibition of S. aureus α-hemolysin and B. anthracis lethal toxin by β-cyclodextrin derivatives VA Karginov, EM Nestorovich, F Schmidtmann, TM Robinson, ... Bioorganic & medicinal chemistry 15 (16), 5424-5431, 2007 | 102 | 2007 |
Pseudomonas aeruginosa porin OprF: properties of the channel EM Nestorovich, E Sugawara, H Nikaido, SM Bezrukov Journal of Biological Chemistry 281 (24), 16230-16237, 2006 | 99 | 2006 |
Diffusion, exclusion, and specific binding in a large channel: a study of OmpF selectivity inversion A Alcaraz, EM Nestorovich, ML López, E García-Giménez, SM Bezrukov, ... Biophysical Journal 96 (1), 56-66, 2009 | 93 | 2009 |
Search for cyclodextrin-based inhibitors of anthrax toxins: synthesis, structural features, and relative activities VA Karginov, EM Nestorovich, A Yohannes, TM Robinson, NE Fahmi, ... Antimicrobial agents and chemotherapy 50 (11), 3740-3753, 2006 | 73 | 2006 |
Polymer partitioning and ion selectivity suggest asymmetrical shape for the membrane pore formed by epsilon toxin EM Nestorovich, VA Karginov, SM Bezrukov Biophysical journal 99 (3), 782-789, 2010 | 63 | 2010 |
Channel-forming bacterial toxins in biosensing and macromolecule delivery PA Gurnev, EM Nestorovich Toxins 6 (8), 2483-2540, 2014 | 61 | 2014 |
Blockage of anthrax PA63 pore by a multicharged high-affinity toxin inhibitor EM Nestorovich, VA Karginov, AM Berezhkovskii, SM Bezrukov Biophysical journal 99 (1), 134-143, 2010 | 60 | 2010 |
Engineering anthrax toxin variants that exclusively form octamers and their application to targeting tumors DD Phillips, RJ Fattah, D Crown, Y Zhang, S Liu, M Moayeri, ER Fischer, ... Journal of Biological Chemistry 288 (13), 9058-9065, 2013 | 51 | 2013 |
Designing inhibitors of anthrax toxin EM Nestorovich, SM Bezrukov Expert opinion on drug discovery 9 (3), 299-318, 2014 | 49 | 2014 |
Obstructing toxin pathways by targeted pore blockage EM Nestorovich, SM Bezrukov Chemical reviews 112 (12), 6388-6430, 2012 | 46 | 2012 |
Tailored ß-Cyclodextrin Blocks the Translocation Pores of Binary Exotoxins from C. Botulinum and C. Perfringens and Protects Cells from Intoxication EM Nestorovich, VA Karginov, MR Popoff, SM Bezrukov, H Barth PloS one 6 (8), e23927, 2011 | 38 | 2011 |
Symmetry requirements for effective blocking of pore-forming toxins: Comparative study with α-, β-, and γ-cyclodextrin derivatives K Yannakopoulou, L Jicsinszky, C Aggelidou, N Mourtzis, TM Robinson, ... Antimicrobial agents and chemotherapy 55 (7), 3594-3597, 2011 | 36 | 2011 |