| Efficient genome editing in zebrafish using a CRISPR-Cas system WY Hwang, Y Fu, D Reyon, ML Maeder, SQ Tsai, JD Sander, ... Nature biotechnology 31 (3), 227-229, 2013 | 3728 | 2013 |
| Engineered CRISPR-Cas9 nucleases with altered PAM specificities BP Kleinstiver, MS Prew, SQ Tsai, VV Topkar, NT Nguyen, Z Zheng, ... Nature 523 (7561), 481-485, 2015 | 1894 | 2015 |
| In vivo drug discovery in the zebrafish LI Zon, RT Peterson Nature reviews Drug discovery 4 (1), 35-44, 2005 | 1698 | 2005 |
| Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism PB Yu, CC Hong, C Sachidanandan, JL Babitt, DY Deng, SA Hoyng, ... Nature chemical biology 4 (1), 33-41, 2008 | 1270 | 2008 |
| Zebrafish as tools for drug discovery CA MacRae, RT Peterson Nature reviews Drug discovery 14 (10), 721-731, 2015 | 1144 | 2015 |
| Targeted gene disruption in somatic zebrafish cells using engineered TALENs JD Sander, L Cade, C Khayter, D Reyon, RT Peterson, JK Joung, ... Nature biotechnology 29 (8), 697-698, 2011 | 834 | 2011 |
| Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA) JD Sander, EJ Dahlborg, MJ Goodwin, L Cade, F Zhang, D Cifuentes, ... Nature methods 8 (1), 67-69, 2011 | 805 | 2011 |
| Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation J Rihel, DA Prober, A Arvanites, K Lam, S Zimmerman, S Jang, ... Science 327 (5963), 348-351, 2010 | 787 | 2010 |
| BMP type I receptor inhibition reduces heterotopic ossification PB Yu, DY Deng, CS Lai, CC Hong, GD Cuny, ML Bouxsein, DW Hong, ... Nature medicine 14 (12), 1363-1369, 2008 | 722 | 2008 |
| Small molecule developmental screens reveal the logic and timing of vertebrate development RT Peterson, BA Link, JE Dowling, SL Schreiber Proceedings of the national academy of sciences 97 (24), 12965-12969, 2000 | 602 | 2000 |
| Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12–rapamycinassociated protein RT Peterson, BN Desai, JS Hardwick, SL Schreiber Proceedings of the National Academy of Sciences 96 (8), 4438-4442, 1999 | 592 | 1999 |
| Rapid behavior-based identification of neuroactive small molecules in the zebrafish D Kokel, J Bryan, C Laggner, R White, CYJ Cheung, R Mateus, D Healey, ... Nature chemical biology 6 (3), 231-237, 2010 | 552 | 2010 |
| Drugs that induce repolarization abnormalities cause bradycardia in zebrafish DJ Milan, TA Peterson, JN Ruskin, RT Peterson, CA MacRae Circulation 107 (10), 1355-1358, 2003 | 506 | 2003 |
| Heritable and precise zebrafish genome editing using a CRISPR-Cas system WY Hwang, Y Fu, D Reyon, ML Maeder, P Kaini, JD Sander, JK Joung, ... PloS one 8 (7), e68708, 2013 | 493 | 2013 |
| Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation RT Peterson, SY Shaw, TA Peterson, DJ Milan, TP Zhong, SL Schreiber, ... Nature biotechnology 22 (5), 595-599, 2004 | 448 | 2004 |
| Use of zebrafish in drug discovery toxicology S Cassar, I Adatto, JL Freeman, JT Gamse, I Iturria, C Lawrence, ... Chemical research in toxicology 33 (1), 95-118, 2019 | 439 | 2019 |
| FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions RT Peterson, PA Beal, MJ Comb, SL Schreiber Journal of Biological Chemistry 275 (10), 7416-7423, 2000 | 429 | 2000 |
| Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors GD Cuny, BY Paul, JK Laha, X Xing, JF Liu, CS Lai, DY Deng, ... Bioorganic & medicinal chemistry letters 18 (15), 4388-4392, 2008 | 415 | 2008 |
| Growth differentiation factor 9: bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions J Peng, Q Li, K Wigglesworth, A Rangarajan, C Kattamuri, RT Peterson, ... Proceedings of the National Academy of Sciences 110 (8), E776-E785, 2013 | 348 | 2013 |
| Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN) JE Foley, JRJ Yeh, ML Maeder, D Reyon, JD Sander, RT Peterson, ... PloS one 4 (2), e4348, 2009 | 318 | 2009 |
Paul B. YuDirector, Cardiovascular Research Center, MGH; Sanders Endowed Chair, Harvard Medical School在 partners.org 的电子邮件经过验证
