Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer E Miele, GP Spinelli, E Miele, F Tomao, S Tomao International journal of nanomedicine, 99-105, 2009 | 1049 | 2009 |
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells E Ferretti, E De Smaele, E Miele, P Laneve, A Po, M Pelloni, A Paganelli, ... The EMBO journal 27 (19), 2616-2627, 2008 | 401 | 2008 |
Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation G Canettieri, L Di Marcotullio, A Greco, S Coni, L Antonucci, P Infante, ... Nature cell biology 12 (2), 132-142, 2010 | 382 | 2010 |
Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy E Miele, GP Spinelli, E Miele, E Di Fabrizio, E Ferretti, S Tomao, A Gulino International journal of nanomedicine, 3637-3657, 2012 | 307 | 2012 |
Hedgehog controls neural stem cells through p53‐independent regulation of Nanog A Po, E Ferretti, E Miele, E De Smaele, A Paganelli, G Canettieri, S Coni, ... The EMBO journal 29 (15), 2646-2658, 2010 | 254 | 2010 |
Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ... Cancer discovery 10 (7), 942-963, 2020 | 215 | 2020 |
Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 185 | 2015 |
Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia V Kumar, R Palermo, C Talora, AF Campese, S Checquolo, D Bellavia, ... Leukemia 28 (12), 2324-2335, 2014 | 177 | 2014 |
MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion G Sebastiani, A Po, E Miele, G Ventriglia, E Ceccarelli, M Bugliani, ... Acta Diabetologica 52, 523-530, 2015 | 152 | 2015 |
Positron Emission Tomography (PET) radiotracers in oncology–utility of 18F-Fluoro-deoxy-glucose (FDG)-PET in the management of patients with non-small-cell lung cancer (NSCLC) E Miele, GP Spinelli, F Tomao, A Zullo, F De Marinis, G Pasciuti, L Rossi, ... Journal of Experimental & Clinical Cancer Research 27, 1-10, 2008 | 141 | 2008 |
Modeling medulloblastoma in vivo and with human cerebellar organoids C Ballabio, M Anderle, M Gianesello, C Lago, E Miele, M Cardano, ... Nature communications 11 (1), 583, 2020 | 134 | 2020 |
Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells S Valente, Y Liu, M Schnekenburger, C Zwergel, S Cosconati, C Gros, ... Journal of medicinal chemistry 57 (3), 701-713, 2014 | 125 | 2014 |
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma A Po, M Silvano, E Miele, C Capalbo, A Eramo, V Salvati, M Todaro, ... Oncogene 36 (32), 4641-4652, 2017 | 103 | 2017 |
Adoptive immunotherapy using PRAME-specific T cells in medulloblastoma D Orlando, E Miele, B De Angelis, M Guercio, I Boffa, M Sinibaldi, A Po, ... Cancer research 78 (12), 3337-3349, 2018 | 84 | 2018 |
Non-canonical Hedgehog/AMPK-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth D D’Amico, L Antonucci, L Di Magno, S Coni, G Sdruscia, A Macone, ... Developmental cell 35 (1), 21-35, 2015 | 83 | 2015 |
microRNA‐17‐92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 N Garg, A Po, E Miele, AF Campese, F Begalli, M Silvano, P Infante, ... The EMBO journal 32 (21), 2819-2832, 2013 | 73 | 2013 |
Aberrant function of the C-terminal tail of HIST1H1E accelerates cellular senescence and causes premature aging E Flex, S Martinelli, A Van Dijck, A Ciolfi, S Cecchetti, E Coluzzi, ... The American Journal of Human Genetics 105 (3), 493-508, 2019 | 69 | 2019 |
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells E Miele, A Po, F Begalli, L Antonucci, A Mastronuzzi, CE Marras, A Carai, ... BMC cancer 17, 1-12, 2017 | 68 | 2017 |
Robot-assisted stereotactic biopsy of diffuse intrinsic pontine glioma: a single-center experience A Carai, A Mastronuzzi, A De Benedictis, R Messina, A Cacchione, ... World neurosurgery 101, 584-588, 2017 | 66 | 2017 |
Long-term survival in metastatic pancreatic cancer. A case report and review of the literature GP Spinelli, A Zullo, A Romiti, M Di Seri, F Tomao, E Miele, B Spalletta, ... Jop 7 (5), 486-491, 2006 | 58 | 2006 |