Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis A Prasad, V Bharathi, V Sivalingam, A Girdhar, BK Patel Frontiers in molecular neuroscience 12, 25, 2019 | 632 | 2019 |
The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion BK Patel, J Gavin-Smyth, SW Liebman Nature cell biology 11 (3), 344-349, 2009 | 309 | 2009 |
“Prion-proof” for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132–405) induces [PIN+] BK Patel, SW Liebman Journal of molecular biology 365 (3), 773-782, 2007 | 157 | 2007 |
Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis SK Park, JY Hong, F Arslan, V Kanneganti, B Patel, A Tietsort, EMH Tank, ... PLoS genetics 13 (5), e1006805, 2017 | 55 | 2017 |
An acridine derivative,[4, 5-bis {(N-carboxy methyl imidazolium) methyl} acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models A Prasad, G Raju, V Sivalingam, A Girdhar, M Verma, A Vats, V Taneja, ... Scientific reports 6 (1), 39490, 2016 | 43 | 2016 |
A high cysteine containing thiol proteinase from the latex of Ervatamia heyneana: purification and comparison with ervatamin B and C from Ervatamia coronaria BK Patel, MV Jagannadham Journal of agricultural and food chemistry 51 (21), 6326-6334, 2003 | 40 | 2003 |
Use of ade1 and ade2 mutations for development of a versatile red/white colour assay of amyloid‐induced oxidative stress in saccharomyces cerevisiae V Bharathi, A Girdhar, A Prasad, M Verma, V Taneja, BK Patel Yeast 33 (12), 607-620, 2016 | 37 | 2016 |
The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization A Prasad, V Sivalingam, V Bharathi, A Girdhar, BK Patel Biochimie 150, 76-87, 2018 | 35 | 2018 |
Wild-type hen egg white lysozyme aggregation in vitro can form self-seeding amyloid conformational variants V Sivalingam, NL Prasanna, N Sharma, A Prasad, BK Patel Biophysical chemistry 219, 28-37, 2016 | 32 | 2016 |
Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase … A Girdhar, V Bharathi, VR Tiwari, S Abhishek, W Deeksha, US Mahawar, ... International journal of biological macromolecules 147, 117-130, 2020 | 31 | 2020 |
Imidazolium tagged acridines: Synthesis, characterization and applications in DNA binding and anti-microbial activities G Raju, S Vishwanath, A Prasad, BK Patel, G Prabusankar Journal of Molecular Structure 1107, 291-299, 2016 | 26 | 2016 |
Familial mutations in fibrinogen Aα (FGA) chain identified in renal amyloidosis increase in vitro amyloidogenicity of FGA fragment V Sivalingam, BK Patel Biochimie 127, 44-49, 2016 | 25 | 2016 |
Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates S Nirwal, V Bharathi, BK Patel Biophysical Chemistry 278, 106678, 2021 | 22 | 2021 |
New insights into in vitro amyloidogenic properties of human serum albumin suggest considerations for therapeutic precautions N Sharma, V Sivalingam, S Maurya, A Prasad, P Khandelwal, SC Yadav, ... FEBS letters 589 (24), 4033-4038, 2015 | 22 | 2015 |
Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of ALS BKP Vidhya Bharathi, Amandeep Girdhar Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868 (6), 118993, 2021 | 14 | 2021 |
Recombinant human semenogelin-1 (Sg1) and Sg1 (1-159) form detergent stable amyloid like aggregates in vitro N Sharma, S Vishwanath, B K Patel Protein and peptide letters 23 (1), 87-96, 2016 | 14 | 2016 |
Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis. Front Mol Neurosci. 2019; 12: 25 A Prasad, V Bharathi, V Sivalingam, A Girdhar, BK Patel Epub 2019/03/07. doi: 10.3389/fnmol. 2019.00025. PubMed PMID: 30837838, 2019 | 11 | 2019 |
Q-Rich Yeast Prion [PSI+] Accelerates Aggregation of Transthyretin, a Non-Q-Rich Human Protein M Verma, A Girdhar, B Patel, NK Ganguly, R Kukreti, V Taneja Frontiers in Molecular Neuroscience 11, 75, 2018 | 10 | 2018 |
Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases S Preethi, V Bharathi, BK Patel International journal of biological macromolecules 176, 186-200, 2021 | 9 | 2021 |
A protocol of using white/red color assay to measure amyloid-induced oxidative stress in Saccharomyces cerevisiae V Bharathi, A Girdhar, BK Patel Bio-protocol 7 (15), e2440-e2440, 2017 | 9 | 2017 |