Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition M Taipale, I Krykbaeva, M Koeva, C Kayatekin, KD Westover, GI Karras, ... Cell 150 (5), 987-1001, 2012 | 912 | 2012 |
The macro domain is an ADP‐ribose binding module GI Karras, G Kustatscher, HR Buhecha, MD Allen, C Pugieux, F Sait, ... The EMBO journal 24 (11), 1911-1920, 2005 | 601 | 2005 |
Widespread macromolecular interaction perturbations in human genetic disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015 | 584 | 2015 |
The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase GI Karras, S Jentsch Cell 141 (2), 255-267, 2010 | 344 | 2010 |
HSP90 shapes the consequences of human genetic variation GI Karras, S Yi, N Sahni, M Fischer, J Xie, M Vidal, AD D’Andrea, ... Cell 168 (5), 856-866. e12, 2017 | 125 | 2017 |
The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance CM Nicolae, ER Aho, AHS Vlahos, KN Choe, S De, GI Karras, ... Journal of Biological Chemistry 289 (19), 13627-13637, 2014 | 112 | 2014 |
Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway GI Karras, M Fumasoni, G Sienski, F Vanoli, D Branzei, S Jentsch Molecular cell 49 (3), 536-546, 2013 | 111 | 2013 |
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis AM Pedley, GI Karras, X Zhang, S Lindquist, SJ Benkovic Biochemistry 57 (23), 3217-3221, 2018 | 22 | 2018 |
Regulation of double-stranded DNA gap repair by the RAD6 pathway S Moertl, GI Karras, T Wismüller, F Ahne, F Eckardt-Schupp DNA repair 7 (11), 1893-1906, 2008 | 20 | 2008 |
Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells BZ Carter, PY Mak, M Muftuoglu, W Tao, B Ke, J Pei, AD Bedoy, ... Blood 142 (12), 1056-1070, 2023 | 7 | 2023 |
An ELISA-based platform for rapid identification of structure-dependent nucleic acid–protein interactions detects novel DNA triplex interactors NG Economos, U Thapar, N Balasubramanian, GI Karras, PM Glazer Journal of Biological Chemistry 298 (10), 2022 | 1 | 2022 |
Selection for robust metabolism in domesticated yeasts is driven by adaptation to Hsp90 stress N Condic, H Amiji, D Patel, WC Shropshire, NO Lermi, Y Sabha, B John, ... Science 385 (6707), eadi3048, 2024 | | 2024 |
Protein-folding chaperones predict structure-function relationships and cancer risk in BRCA1 mutation carriers B Gracia, P Montes, AM Gutierrez, B Arun, GI Karras Cell reports 43 (2), 2024 | | 2024 |
Ethanol Drives Evolution of Hsp90-Dependent Robustness by Redundancy in Yeast Domestication D Patel, H Amiji, W Shropshire, N Condic, NO Lermi, Y Sabha, B John, ... bioRxiv, 2023.07. 21.547572, 2023 | | 2023 |
Epichaperome Inhibition Targets Kinase and TP53 Mutant Therapy Resistant AML BZ Carter, PY Mak, W Tao, LB Ostermann, Y Nishida, N Pemmaraju, ... Blood 140 (Supplement 1), 5930-5931, 2022 | | 2022 |
2022 Herbert Tabor Early Career Investigator Awards: Call for nominations KT Farabaugh, A Toker, G DeMartino Journal of Biological Chemistry 298 (10), 2022 | | 2022 |
Delineating Structure-Function Relationships in FANCA Using Chaperones N Kota, BR Gracia, NJ Condic, GI Karras | | 2022 |
Investigating the genetic architecture of a Hsp90-dependent trait in the budding yeast Saccharomyces cerevisiae SY Ding, H Amiji, D Patel, GI Karras The University of Texas MD Anderson Cancer Center, 2021 | | 2021 |
High-Throughput ELISA Screening for Mechanisms of Non-Enzymatic PNA-Mediated Gene Editing NG Economos, U Thapar, J Tansky, WM Saltzman, GI Karras, PM Glazer MOLECULAR THERAPY 28 (4), 449-449, 2020 | | 2020 |
Claudia M. Nicolae1, Erin R. Aho1, Alexander HS Vlahos1, Katherine N. Choe1, Subhajyoti De2, 3, 4 GI Karras, GL Moldovan DNA 7 (8), 21-22, 2014 | | 2014 |