Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding MC Vogt, L Paeger, S Hess, SM Steculorum, M Awazawa, B Hampel, ... Cell 156 (3), 495-509, 2014 | 372 | 2014 |
AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue SM Steculorum, J Ruud, I Karakasilioti, H Backes, LE Ruud, K Timper, ... Cell 165 (1), 125-138, 2016 | 263 | 2016 |
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons T Klöckener, S Hess, BF Belgardt, L Paeger, LAW Verhagen, A Husch, ... Nature neuroscience 14 (7), 911-918, 2011 | 256 | 2011 |
Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance E Tsaousidou, L Paeger, BF Belgardt, M Pal, CM Wunderlich, H Brönneke, ... Cell reports 9 (4), 1495-1506, 2014 | 112 | 2014 |
AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival ER Almajan, R Richter, L Paeger, P Martinelli, E Barth, T Decker, ... The Journal of clinical investigation 122 (11), 4048-4058, 2012 | 110 | 2012 |
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting N Biglari, I Gaziano, J Schumacher, J Radermacher, L Paeger, P Klemm, ... Nature neuroscience 24 (7), 913-929, 2021 | 87 | 2021 |
PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding A Jais, L Paeger, T Sotelo-Hitschfeld, S Bremser, M Prinzensteiner, ... Neuron 106 (6), 1009-1025. e10, 2020 | 87 | 2020 |
Hypothalamic UDP increases in obesity and promotes feeding via P2Y6-dependent activation of AgRP neurons SM Steculorum, L Paeger, S Bremser, N Evers, Y Hinze, M Idzko, ... Cell 162 (6), 1404-1417, 2015 | 82 | 2015 |
Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin L Paeger, I Karakasilioti, J Altmüller, P Frommolt, J Brüning, ... Elife 6, e25770, 2017 | 57 | 2017 |
Energy imbalance alters Ca2+ handling and excitability of POMC neurons L Paeger, A Pippow, S Hess, M Paehler, AC Klein, A Husch, C Pouzat, ... Elife 6, e25641, 2017 | 54 | 2017 |
AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice AJ Newton, S Hess, L Paeger, MC Vogt, J Fleming Lascano, EA Nillni, ... Endocrinology 154 (1), 172-183, 2013 | 53 | 2013 |
Calcium current diversity in physiologically different local interneuron types of the antennal lobe A Husch, M Paehler, D Fusca, L Paeger, P Kloppenburg Journal of Neuroscience 29 (3), 716-726, 2009 | 50 | 2009 |
Distinct Electrophysiological Properties in Subtypes of Nonspiking Olfactory Local Interneurons Correlate With Their Cell Type–Specific Ca2+ Current Profiles A Husch, M Paehler, D Fusca, L Paeger, P Kloppenburg Journal of neurophysiology 102 (5), 2834-2845, 2009 | 48 | 2009 |
Inhibition of P2Y6 signaling in AgRP neurons reduces food intake and improves systemic insulin sensitivity in obesity SM Steculorum, K Timper, LE Ruud, N Evers, L Paeger, S Bremser, ... Cell Reports 18 (7), 1587-1597, 2017 | 42 | 2017 |
Mild impairment of mitochondrial OXPHOS promotes fatty acid utilization in POMC neurons and improves glucose homeostasis in obesity K Timper, L Paeger, C Sánchez-Lasheras, L Varela, A Jais, H Nolte, ... Cell reports 25 (2), 383-397. e10, 2018 | 32 | 2018 |
KATP-Channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis S Tovar, L Paeger, S Hess, DA Morgan, AC Hausen, HS Brönneke, ... Cell metabolism 18 (3), 445-455, 2013 | 32 | 2013 |
Neuronal actin dynamics, spine density and neuronal dendritic complexity are regulated by CAP2 A Kumar, L Paeger, K Kosmas, P Kloppenburg, AA Noegel, VS Peche Frontiers in cellular neuroscience 10, 180, 2016 | 26 | 2016 |
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data A Ballweg, C Klaus, L Vogler, S Katzdobler, K Wind, A Zatcepin, SI Ziegler, ... Journal of Neuroinflammation 20 (1), 68, 2023 | 13 | 2023 |
Analysis of neuronal Ca2+ handling properties by combining perforated patch clamp recordings and the added buffer approach S Hess, C Pouzat, L Paeger, A Pippow, P Kloppenburg Cell Calcium 97, 102411, 2021 | 10 | 2021 |
Cortical circuit dysfunction in a mouse model of alpha-synucleinopathy in vivo S Blumenstock, F Sun, C Klaus, P Marinković, C Sgobio, L Paeger, ... Brain Communications 3 (4), fcab273, 2021 | 8 | 2021 |