Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration Y Zhang, A Desai, SY Yang, KB Bae, MI Antczak, SP Fink, S Tiwari, ... Science 348 (6240), aaa2340, 2015 | 289 | 2015 |
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer Y Hao, Y Samuels, Q Li, D Krokowski, BJ Guan, C Wang, Z Jin, B Dong, ... Nature communications 7 (1), 11971, 2016 | 256 | 2016 |
Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde SP Fink, GR Reddy, LJ Marnett Proceedings of the National Academy of Sciences 94 (16), 8652-8657, 1997 | 244 | 1997 |
Taxol-induced flexibility of microtubules and its reversal by MAP-2 and Tau. RB Dye, SP Fink, RC Williams Jr Journal of Biological Chemistry 268 (10), 6847-6850, 1993 | 192 | 1993 |
15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors M Yan, SJ Myung, SP Fink, E Lawrence, J Lutterbaugh, P Yang, X Zhou, ... Proceedings of the National Academy of Sciences 106 (23), 9409-9413, 2009 | 130 | 2009 |
TGF-β-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines SP Fink, D Mikkola, JKV Willson, S Markowitz Oncogene 22 (9), 1317-1323, 2003 | 130 | 2003 |
Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD) SP Fink, M Yamauchi, R Nishihara, S Jung, A Kuchiba, K Wu, E Cho, ... Science translational medicine 6 (233), 233re2-233re2, 2014 | 118 | 2014 |
Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro KA Johnson, SP Fink, LJ Marnett Journal of Biological Chemistry 272 (17), 11434-11438, 1997 | 117 | 1997 |
Transforming growth factor-β-induced growth inhibition in a Smad4 mutant colon adenoma cell line SP Fink, SE Swinler, JD Lutterbaugh, J Massagué, S Thiagalingam, ... Cancer research 61 (1), 256-260, 2001 | 116 | 2001 |
Misincorporation of Nucleotides opposite Five-Membered Exocyclic Ring Guanine Derivatives by Escherichia c oli Polymerases in Vitro and in Vivo: 1, N 2-Ethenoguanine, 5, 6, 7 … S Langouët, AN Mican, M Müller, SP Fink, LJ Marnett, SA Muhle, ... Biochemistry 37 (15), 5184-5193, 1998 | 92 | 1998 |
Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival SP Fink, LL Myeroff, R Kariv, P Platzer, B Xin, D Mikkola, E Lawrence, ... Oncotarget 6 (31), 30500, 2015 | 75 | 2015 |
Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia B Xin, P Platzer, SP Fink, L Reese, A Nosrati, JKV Willson, K Wilson, ... Oncogene 24 (4), 724-731, 2005 | 57 | 2005 |
MutS recognition of exocyclic DNA adducts that are endogenous products of lipid oxidation KA Johnson, ML Mierzwa, SP Fink, LJ Marnett Journal of Biological Chemistry 274 (38), 27112-27118, 1999 | 56 | 1999 |
Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis SH Choi, BG Kim, J Robinson, S Fink, M Yan, MB Sporn, SD Markowitz, ... The Journal of clinical investigation 124 (6), 2472-2482, 2014 | 55 | 2014 |
Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase C Guo, X Zhang, SP Fink, P Platzer, K Wilson, JKV Willson, Z Wang, ... Cancer research 68 (15), 6118-6126, 2008 | 51 | 2008 |
Refractory ceramic fibers activate alveolar macrophage eicosanoid and cytokine release GD Leikauf, SP Fink, ML Miller, JE Lockey, KE Driscoll Journal of Applied Physiology 78 (1), 164-171, 1995 | 41 | 1995 |
Inactivating Mutation in the Prostaglandin Transporter Gene, SLCO2A1, Associated with Familial Digital Clubbing, Colon Neoplasia, and NSAID Resistance K Guda, SP Fink, GL Milne, N Molyneaux, L Ravi, SM Lewis, ... Cancer prevention research 7 (8), 805-812, 2014 | 37 | 2014 |
15-hydroxyprostaglandin dehydrogenase is downregulated and exhibits tumor suppressor activity in gastric cancer HJ Song, SJ Myung, IW Kim, JY Jeong, YS Park, SM Lee, WH Nam, ... Cancer investigation 29 (4), 257-265, 2011 | 30 | 2011 |
Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility CL Thompson, SP Fink, JD Lutterbaugh, RC Elston, ML Veigl, ... PloS one 8 (5), e64122, 2013 | 22 | 2013 |
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs SP Fink, DM Dawson, Y Zhang, A Kresak, EG Lawrence, P Yang, Y Chen, ... Carcinogenesis 36 (2), 291-298, 2015 | 20 | 2015 |