| On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site EI Vrettos, G Mező, AG Tzakos Beilstein journal of organic chemistry 14 (1), 930-954, 2018 | 164 | 2018 |
| Probing the interaction of a quercetin bioconjugate with Bcl‐2 in living human cancer cells with in‐cell NMR spectroscopy A Primikyri, N Sayyad, G Quilici, EI Vrettos, K Lim, SW Chi, G Musco, ... FEBS letters 592 (20), 3367-3379, 2018 | 46 | 2018 |
| Unveiling and tackling guanidinium peptide coupling reagent side reactions towards the development of peptide-drug conjugates EI Vrettos, N Sayyad, EM Mavrogiannaki, E Stylos, AD Kostagianni, ... Rsc Advances 7 (80), 50519-50526, 2017 | 46 | 2017 |
| Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL TF Kellici, MV Chatziathanasiadou, MS Lee, N Sayyad, EG Geromichalou, ... Organic & biomolecular chemistry 15 (37), 7956-7976, 2017 | 28 | 2017 |
| Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable “click” oxime bond tethers and preclinical evaluation against prostate cancer EI Vrettos, T Karampelas, N Sayyad, A Kougioumtzi, N Syed, T Crook, ... European journal of medicinal chemistry 211, 113018, 2021 | 26 | 2021 |
| Development of bioactive gemcitabine-D-Lys6-GnRH prodrugs with linker-controllable drug release rate and enhanced biopharmaceutical profile N Sayyad, EI Vrettos, T Karampelas, CM Chatzigiannis, K Spyridaki, ... European journal of medicinal chemistry 166, 256-266, 2019 | 22 | 2019 |
| Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid AD Tsiailanis, A Renziehausen, S Kiriakidi, EI Vrettos, GS Markopoulos, ... Free Radical Biology and Medicine 160, 391-402, 2020 | 19 | 2020 |
| Amplifying and broadening the cytotoxic profile of quercetin in cancer cell lines through bioconjugation MV Chatziathanasiadou, EG Geromichalou, N Sayyad, EI Vrettos, ... Amino Acids 50, 279-291, 2018 | 16 | 2018 |
| Design principles governing the development of theranostic anticancer agents and their nanoformulations with photoacoustic properties SG Kyrkou, EI Vrettos, D Gorpas, T Crook, N Syed, AG Tzakos Pharmaceutics 14 (2), 362, 2022 | 8 | 2022 |
| Single peptide backbone surrogate mutations to regulate angiotensin GPCR subtype selectivity EI Vrettos, IE Valverde, A Mascarin, PN Pallier, L Cerofolini, M Fragai, ... Chemistry–A European Journal 26 (47), 10690-10694, 2020 | 8 | 2020 |
| Development of novel GnRH and Tat 48–60 based luminescent probes with enhanced cellular uptake and bioimaging profile A Kougioumtzi, MV Chatziathanasiadou, EI Vrettos, N Sayyad, M Sakka, ... Dalton Transactions 50 (26), 9215-9224, 2021 | 7 | 2021 |
| Development of a novel conjugatable sunitinib analogue validated through in vitro and in vivo preclinical settings MA El Mubarak, I Leontari, G Efstathia, EI Vrettos, A kadar Shaikh, ... Journal of Chromatography B 1092, 515-523, 2018 | 7 | 2018 |
| Construction of Peptide-Drug Conjugates for Selective Targeting of Malignant Tumor Cells EI Vrettos, AG Tzakos Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols …, 2021 | 6 | 2021 |
| Design, Synthesis, and Antitumor Evaluation of an Opioid Growth Factor Bioconjugate Targeting Pancreatic Ductal Adenocarcinoma J Budka, D Debowski, S Mai, M Narajczyk, S Hac, K Rolka, EI Vrettos, ... Pharmaceutics 16 (2), 283, 2024 | 1 | 2024 |
| A fluorescent gemcitabine prodrug that follows a nucleoside transporter‐independent internalization and bears enhanced therapeutic efficacy with respect to gemcitabine E Vrettos, S Kyrkou, V Zoi, M Giannakopoulou, M Chatziathanasiadou, ... Chemistry–A European Journal, e202401327, 2024 | | 2024 |
| Hypoxia-Activated Theragnostic Prodrugs (HATPs): Current State and Future Perspectives S Bhuniya, EI Vrettos Pharmaceutics 16 (4), 557, 2024 | | 2024 |
| Development of a DHA-Losartan hybrid as a potent inhibitor of multiple pathway-induced platelet aggregation AD Tsiailanis, EI Vrettos, M Choleva, S Kiriakidi, AM Ganai, TK Patha, ... Journal of Biomolecular Structure and Dynamics 40 (24), 13889-13900, 2022 | | 2022 |
| Cover Feature: Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity (Chem. Eur. J. 47/2020) EI Vrettos, IE Valverde, A Mascarin, PN Pallier, L Cerofolini, M Fragai, ... Chemistry-A European Journal, 2020 | | 2020 |
| Development of bioactive gemcitabine-D-Lys 6-GnRH prodrugs with linker-controllable drug release rate and biopharmaceutical profile N Sayyad, EI Vrettos, T Karampelas, CM Chatzigiannis, K Spyridaki, ... | | 2019 |
| In-cell NMR spectroscopy applied in the study of ligand-protein interactions in living cancer cells A Primikyri, N Sayyad, G Quilici, E Vrettos, K Lim, SW Chi, G Musco, ... | | 2019 |
Andreas TzakosAssociate Professor在 cc.uoi.gr 的电子邮件经过验证
