An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion JD Klement, AV Paschall, PS Redd, ML Ibrahim, C Lu, D Yang, E Celis, ... The Journal of clinical investigation 128 (12), 5549-5560, 2018 | 221 | 2018 |
Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes C Lu, JD Klement, ML Ibrahim, W Xiao, PS Redd, A Nayak-Kapoor, ... Journal for immunotherapy of cancer 7, 1-11, 2019 | 109 | 2019 |
Myeloid-derived suppressor cells produce IL-10 to elicit DNMT3b-dependent IRF8 silencing to promote colitis-associated colon tumorigenesis ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, ... Cell reports 25 (11), 3036-3046. e6, 2018 | 84 | 2018 |
IFNAR1 controls autocrine type I IFN regulation of PD-L1 expression in myeloid-derived suppressor cells W Xiao, JD Klement, C Lu, ML Ibrahim, K Liu The Journal of Immunology 201 (1), 264-277, 2018 | 77 | 2018 |
Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells AD Smith, C Lu, D Payne, AV Paschall, JD Klement, PS Redd, ML Ibrahim, ... Cancer research 80 (15), 3145-3156, 2020 | 60 | 2020 |
SETD1B activates iNOS expression in myeloid-derived suppressor cells PS Redd, ML Ibrahim, JD Klement, SK Sharman, AV Paschall, D Yang, ... Cancer Research 77 (11), 2834-2843, 2017 | 59 | 2017 |
Biochemical modifications and neuronal damage in brain of young and adult rats after long-term exposure to mobile phone radiations TK Motawi, HA Darwish, YM Moustafa, MM Labib Cell biochemistry and biophysics 70, 845-855, 2014 | 46 | 2014 |
Loss of fas expression and function is coupled with colon cancer resistance to immune checkpoint inhibitor immunotherapy W Xiao, ML Ibrahim, PS Redd, JD Klement, C Lu, D Yang, NM Savage, ... Molecular Cancer Research 17 (2), 420-430, 2019 | 40 | 2019 |
Expression profiles and function of IL6 in polymorphonuclear myeloid-derived suppressor cells ML Ibrahim, C Lu, JD Klement, PS Redd, D Yang, AD Smith, K Liu Cancer Immunology, Immunotherapy 69, 2233-2245, 2020 | 20 | 2020 |
H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells PS Redd, C Lu, JD Klement, ML Ibrahim, G Zhou, T Kumai, E Celis, K Liu Oncoimmunology 7 (9), e1483302, 2018 | 16 | 2018 |
Combination IFNβ and membrane-stable CD40L maximize tumor dendritic cell activation and lymph node trafficking to elicit systemic T-cell immunity H Zheng, X Yu, ML Ibrahim, D Foresman, M Xie, JO Johnson, TA Boyle, ... Cancer Immunology Research 11 (4), 466-485, 2023 | 5 | 2023 |
Repression of osteopontin by IRF8 regulates a novel immunosuppressive checkpoint JD Klement, AV Paschall, PS Redd, ML Ibrahim, C Lu, D Yang, E Celis, ... The Journal of Immunology 202 (1_Supplement), 195.26-195.26, 2019 | 2 | 2019 |
IRF8 deficiency in colonic epithelial cells promotes inflammation-mediated colon tumorigenesis and myeloid-derived suppressor cell differentiation. ML Ibrahim, K Liu The Journal of Immunology 198 (1_Supplement), 66.20-66.20, 2017 | 2 | 2017 |
Histone Deacetylase Inhibitors Directly Modulate T Cell Gene Expression and Signaling and Promote Development of Effector-Exhausted T Cells in Murine Tumors ML Ibrahim, H Zheng, ML Barlow, Y Latif, Z Chen, X Yu, AA Beg The Journal of Immunology, 2024 | 1 | 2024 |
Autocrine IL6 activates the STAT3-DNMT axis to silence the TNFa-RIP1 necroptosis pathway to sustain myeloid-derived suppressor cell survival and accumulation AD Smith, C Lu, D Payne, AV Paschall, JD Klement, PS Redd, M Ibrahim, ... The Journal of Immunology 204 (1_Supplement), 164.10-164.10, 2020 | 1 | 2020 |
Chronic inflammation activates IL6 signaling to upregulate DNMT1 and DNMT3b to promote colon tumorigenesis ML Ibrahim, JD Klement, D Payne, C Lu, PS Redd, K Liu Cancer Research 78 (13_Supplement), 5744-5744, 2018 | 1 | 2018 |
Sotorasib, a selective G12C K-RAS inhibitor, modulates the tumor microenvironment to promote TNFα and IFNγ signaling and augment immunotherapy response ML Ibrahim, D Foresman, H Zheng, EB Haura, D Abate-Daga, X Yu, ... Cancer Research 83 (7_Supplement), 3264-3264, 2023 | | 2023 |
NF-kB1 induces T cell dysfunction to promote colon tumorigenesis C Lu, JD Klement, W Xiao, ML Ibrahim, AD Smith, D Yang, D Browning, ... The Journal of Immunology 204 (1_Supplement), 165.32-165.32, 2020 | | 2020 |
Neutral ceramidase regulates ferroptosis in myeloid-derived suppressor cells C Lu, D Yang, PS Redd, ML Ibrahim, JD Klement, AD Smith, T Albers, ... The Journal of Immunology 204 (1_Supplement), 164.12-164.12, 2020 | | 2020 |
Ceramide mimetics regulation of tumor cell response to immune checkpoint inhibitor immunotherapy PS Redd, C Lu, JD Klement, M Ibrahim, D Yang, D Payne, I Lebedyeva, ... Cancer Research 79 (13_Supplement), 2263-2263, 2019 | | 2019 |